Results 71 to 80 of about 157,236 (308)

von Willebrand Disease: The diagnosis and management of this bleeding disorder

Medical Journal of Babylon, 2020
von Willebrand disease (vWD) is one of the most common bleeding disorders, first described by Erik von Willebrand in the Aland Islands. It occurs as a result of decreased or abnormal von Willebrand factor (vWF), a factor that is needed in the process of ...
Basim A. Abd, Nawrass J Al-Salihi
doaj   +1 more source

Septal Release: A Targeted Surgical Strategy for Recurrent Epistaxis

Eye &ENT Research, EarlyView.
ABSTRACT Background Recurrent epistaxis is a common pediatric condition that is typically managed with conservative therapies, but a subset of patients require surgical intervention after treatment failure. We seek to describe the efficacy of septal release for refractory pediatric epistaxis patients. Objective To compare outcomes of septal release for
Alexandra Welschmeyer, Daniel Karasik, Christopher L. Crafton, Eve Tranchito, Sarah Ridge, Cyrus C. Rabbani, Jay Shah   +6 more
wiley   +1 more source

Von willebrand disease: An overview

Indian Journal of Pharmaceutical Sciences, 2011
Most commonly inherited bleeding disorder, first described in Aland Islands by Erik von Willebrand. It occurs as a result of decrease in plasma levels or defect in von Willebrand factor which is a large multimeric glycoprotein. Monomers of this glycoprotein undergo N-glycosylation to form dimers which get arranged to give multimers. Binding with plasma
Bharati, K. Pavani, Prashanth, U. Ram
openaire   +3 more sources

Commonalities of platelet dysfunction in heart failure with preserved ejection fraction and underlying comorbidities

ESC Heart Failure, Volume 12, Issue 2, Page 1013-1028, April 2025.
Abstract Heart failure with preserved ejection fraction (HFpEF) is characterized by a lack of a specific targeted treatment and a complex, partially unexplored pathophysiology. Common comorbidities associated with HFpEF are hypertension, atrial fibrillation, obesity and diabetes.
Giorgia D'Italia, Blanche Schroen, Judith M.E.M. Cosemans   +2 more
wiley   +1 more source

Patient with Dyspnea, Dysphagia and Menorrhagia: Plummer — Vinson Syndrome Against the Background of von Willebrand Disease

Российский журнал гастроэнтерологии, гепатологии, колопроктологии
Aim: to present a clinical observation of a patient with Plummer — Vinson syndrome against the background of von Willebrand disease.Key points. A 40-years-old woman presented to the hematology department of our hospital with fatigue, dizziness, dyspnea ...
A. A. Saenko, A. I. Dolgushina, O. V. Korobitsyna, E. R. Olevskaya, A. O. Khikhlova, A. S. Kuznezowa, V. V. Genkel, G. M. Khusainova   +7 more
doaj   +1 more source

CardiLect: A combined cross‐species lectin histochemistry protocol for the automated analysis of cardiac remodelling

ESC Heart Failure, Volume 12, Issue 2, Page 1398-1415, April 2025.
Abstract Background Cardiac remodelling, a crucial aspect of heart failure, is commonly investigated in preclinical models by quantifying cardiomyocyte cross‐sectional area (CSA) and microvascular density (MVD) via histological methods, such as immunohistochemistry.
Tamás G. Gergely, Tamás Kovács, Andrea Kovács, Viktória E. Tóth, Nabil V. Sayour, Gábor M. Mórotz, Csenger Kovácsházi, Gábor B. Brenner, Zsófia Onódi, Balázs Enyedi, Domokos Máthé, Przemyslaw Leszek, Zoltán Giricz, Péter Ferdinandy, Zoltán V. Varga   +14 more
wiley   +1 more source

Frequency Assessment of the H817Q (2451T→A) Variant of von Willebrand Gene in Individuals without Hemorrhagic Signs [PDF]

Journal of Kerman University of Medical Sciences, 2016
Background and Aims:‎ Von Willebrand disease is a bleeding disorder caused by quantitative or functional defects in von Willebrand factor. The disease is found in up to 1 percent of the population.
Mansoureh Bakhtiari, Shirin Shahbazi, Mehrdad Hashemi   +2 more
doaj  

Pseudo (Platelet-type) von Willebrand disease in pregnancy: a case report

BMC Pregnancy and Childbirth, 2013
Background Pseudo (platelet-type)-von Willebrand disease is a rare autosomal dominant bleeding disorder caused by an abnormal function of the glycoprotein lb protein; the receptor for von Willebrand factor.
Grover Neetu, Boama Vincent, Chou Munazzah Rifat   +2 more
doaj   +1 more source

Individualizing dosing frequency may improve the efficacy of prophylaxis in patients with von Willebrand disease—a WIL-31 subanalysis

Research and Practice in Thrombosis and Haemostasis
Background: The efficacy and safety of prophylaxis with wilate, a plasma-derived von Willebrand factor/factor VIII concentrate, was demonstrated in patients with von Willebrand disease of all types in the WIL-31 study.
Robert F. Sidonio, Jr., Ana Boban, Toshko Lissitchkov, Laszlo Nemes, Vladimir Vdovin, Claudia Djambas Khayat   +5 more
doaj   +1 more source

Relevance of platelet desialylation and thrombocytopenia in type 2B von Willebrand disease: preclinical and clinical evidence

Haematologica, 2019
Patients with type 2B von Willebrand disease (vWD) (caused by gain-of-function mutations in the gene coding for von Willebrand factor) display bleeding to a variable extent and, in some cases, thrombocytopenia.
Annabelle Dupont, Christelle Soukaseum, Mathilde Cheptou, Frédéric Adam, Thomas Nipoti, Marc-Damien Lourenco-Rodrigues, Paulette Legendre, Valérie Proulle, Antoine Rauch, Charlotte Kawecki, Marijke Bryckaert, Jean-Philippe Rosa, Camille Paris, Catherine Ternisien, Pierre Boisseau, Jenny Goudemand, Delphine Borgel, Dominique Lasne, Pascal Maurice, Peter J. Lenting, Cécile V. Denis, Sophie Susen, Alexandre Kauskot   +22 more
doaj   +1 more source