Results 91 to 100 of about 52,208 (254)

Paciente portadora de doença de von Willebrand submetida a cirurgia da valva mitral: uma estratégia para o controle da coagulopatia Patient with von Willebrand disease undergoing mitral valve repair: a strategy for the control of the coagulopathy

Arquivos Brasileiros de Cardiologia, 2007
Relatamos o caso de uma mulher de 60 anos portadora da doença de von Willebrand tipo I, submetida a cirurgia da valva mitral. A paciente necessitou de cuidados especiais em razão da coagulopatia e foi necessária a utilização de concentrado de fator VIII (
Ally Nader Roquetti Saroute, Carlos Manuel de Almeida Brandão, Marco Antônio Vieira Guedes, Cyrillo Cavalheiro Filho, Pablo Maria Alberto Pomerantzeff   +4 more
doaj   +1 more source

Menstrual suppression to decrease intrauterine device expulsion in adolescents with inherited bleeding disorders

International Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 421-423, April 2025.
Peter H. Cygan, Kelly M. Kons, Megan H. Fiorillo, Tonya S. Wright   +3 more
wiley   +1 more source

Platelet function in patients undergoing major non‐cardiac vascular surgery (PLUGS): a prospective cohort study*

Anaesthesia, EarlyView.
Summary Introduction Patients who require major vascular surgery often receive antiplatelet therapy for primary or secondary prevention of cardiovascular disease. Clopidogrel resistance and variability in platelet recovery after drug discontinuation pose clinical challenges, particularly for regional anaesthesia and blood management.
Akshay Shah, Grace Polley, Kasia Bera, Keith Maher, Stephen Von‐Kier, Antonio Barbosa, Louis Corrigan, Sabeena Sharma, Peter Baker, Stuart R. McKechnie, Michael J. Desborough, on behalf of the PLUGS Investigators   +11 more
wiley   +1 more source

Individualizing dosing frequency may improve the efficacy of prophylaxis in patients with von Willebrand disease—a WIL-31 subanalysis

Research and Practice in Thrombosis and Haemostasis
Background: The efficacy and safety of prophylaxis with wilate, a plasma-derived von Willebrand factor/factor VIII concentrate, was demonstrated in patients with von Willebrand disease of all types in the WIL-31 study.
Robert F. Sidonio, Jr., Ana Boban, Toshko Lissitchkov, Laszlo Nemes, Vladimir Vdovin, Claudia Djambas Khayat   +5 more
doaj   +1 more source

Mesenchymal Stem Cells From a Klinefelter Syndrome Patient: Functional Characterization and Therapeutic Implications

Andrology, EarlyView.
ABSTRACT Background Cell therapy, particularly those utilizing mesenchymal stem/stromal cells (MSCs), is gaining traction as a therapeutic option for regenerative treatment in patients with limited therapeutic options. Although the safety of MSC‐based interventions is well established, uncertainties remain regarding how genetic abnormalities and ...
Marzena Zychowicz, Wioletta Lech, Anna Figiel‐Dabrowska, Marta Kot, Magdalena Murzyn, Natalia Malawska, Barbara Pienkowska‐Grela, Zuzanna Sandowska‐Markiewicz, Iwona Ziolkowska‐Suchanek, Agnieszka Zimna, Tomasz Oldak, Natalia Rozwadowska, Anna Sarnowska   +12 more
wiley   +1 more source

A Comparison of Endothelial Cell-Selective Adhesion Molecule and von Willebrand Factor Expression in Breast Cancer Growth and Metastasis

Middle East Journal of Cancer, 2018
Background: Angiogenesis is the process of new blood vessels formation that contribute to tumor growth and metastasis. Endothelial cell-selective adhesion molecule is one of the proteins that expresses in vascular endothelial cells.
M Husni Cangara, Mochammad Hatta, Upik A Miskad, Syarifuddin Wahid   +3 more
doaj  

Comparison of a Miniaturized Implantable Two‐Stage Rotodynamic Blood Pump to Equivalent Single‐Stage Concepts

Artificial Organs, EarlyView.
This study aims to evaluate the potential of a multistage pump design to enhance hemocompatibility in left ventricular assist devices. We found that the two‐stage concept offers favorable hemolysis measures compared to single‐stage designs, as the reduction in peak shear stresses outweighs the disadvantage associated with prolonged residence time ...
Sarah Linnemeier, Bente Thamsen, Stefan Maric, Bernhard Semlitsch, Benjamin Torner, Daniel Zimpfer, Marcus Granegger   +6 more
wiley   +1 more source

Device‐Induced Blood Damage in Pump‐Assisted Circulation: A Comparative Study of HeartMate III and BrioVAD Pumps

Artificial Organs, EarlyView.
Shear‐induced blood damage—including hemolysis, platelet and neutrophil injury, and von Willebrand factor (vWF) degradation—was evaluated for the BrioVAD and HM3 using an in vitro circulatory loop under clinically relevant conditions. Across 15 biomarkers (n > 6 per group), no significant differences were observed between the two devices.
Wenji Sun, Kiersten P. Clark, Douglas Tran, John C. Vandenberge, Nancy Kim, Shigang Wang, Anik Tarafder, Randy Perez, Bartley P. Griffith, Dong Han   +9 more
wiley   +1 more source

Clinical burden and healthcare resource use of congenital thrombotic thrombocytopenic purpura in England: A linked primary and secondary care data analysis

British Journal of Haematology, EarlyView.
Summary Congenital thrombotic thrombocytopenic purpura (cTTP) is an ultra rare haematological disorder. This study aimed to estimate the clinical burden, healthcare resource use (HCRU) and associated costs of cTTP in England using primary and secondary care data. A retrospective cohort study was undertaken using the Clinical Practice Research Datalink (
Erin Barker, Will Lester, Heather Riley, Monica Garrett, Amie Padhiar, Annie Berkley, Sudhakar Manne, Umesh Doobaree, Oliver Heard   +8 more
wiley   +1 more source

Von Willebrand hastalığı’nda oral cerrahi yaklaşım: olgu sunumu

Cumhuriyet Dental Journal, 2011
Von Willebrand Disease (VWD) is a hereditary coagulation disorder characterized by a deficient or abnormal plasma protein known as the von Willebrand factor (vWF).
Ahmet Arslan, Ediz Deniz
doaj