Failure of voriconazole to cure disseminated zygomycosis in an immunocompromised child [PDF]
, 2018 Voriconazole is increasingly used as a first-line agent for empirical antifungal therapy of prolonged febrile neutropenia in paediatric cancer patients. We describe the case of a 9-year-old patient with stage IV Burkitt lymphoma, who developed pulmonary ...
Aebi, Christoph +6 more
core
Infection and Drug ResistanceHong Lu,* Yanmei Mao,* Ying Zeng, Pengyu Li, Pan Yan, Qunzhi Shi, Lin Liu Department of Pharmacy, The Affiliated Changsha Central Hospital, Hengyang Medical School, University of South China, Changsha, Hunan, People’s Republic of China*These ...
Lu H +6 more
doaj
Synergism of Voriconazole and Terbinafine against Candida albicans Isolates from Human Immunodeficiency Virus-Infected Patients with Oropharyngeal Candidiasis [PDF]
, 2001 Michael Weig, Frank‐Michael C. Müller
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In vitro activity of fluconazole and voriconazole against clinical isolates of Candida spp. by E-test method. [PDF]
, 2010 The in vitro susceptibility of clinical Candida isolates towards fluconazole and voriconazole was determined using the E-test method. A total of 41 clinical isolates recovered from patients since 2004 until 2009 from two local hospitals in Kuala Lumpur ...
Chong, Pei Pei +3 more
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Clinical Case Reports, Volume 13, Issue 10, October 2025.ABSTRACT There is an increased risk of invasive aspergillosis (IA) during the induction of acute lymphoblastic leukemia (ALL) because of the use of cytoreductive chemotherapy and high‐dose steroids. This case demonstrates the utility of metagenomic next‐generation sequencing and repeat sampling in clarifying complex infections and highlights ...
Yutong Liu +9 more
wiley +1 more source
Metamizole induces voriconazole metabolism and results in subtherapeutic voriconazole concentrations
British Journal of Clinical PharmacologyAimsVoriconazole is extensively metabolized via cytochrome P450 (CYP) enzymes, predominantly CYP2C19 and CYP3A4. Drugs influencing the activity or expression of CYP enzymes can cause clinically relevant changes in the metabolism and voriconazole exposure. Metamizole is known to induce CYP3A4 and CYP2C19.
Simone D. Baan +3 more
openaire +2 more sources
eJHaem, Volume 6, Issue 5, October 2025.ABSTRACT Introduction Invasive fungal infection (IFI) after chimeric antigen receptor (CAR) T‐cell therapy is less common than bacterial and viral infections, but can be fatal once it develops. As most cases occur within 30 days after CAR T‐cell infusion, late‐onset IFI—particularly mould infection—appears to be under‐recognised.
Daisuke Ikeda +16 more
wiley +1 more source
Challenging Recommended Oral and Intravenous Voriconazole Doses for Improved Efficacy and Safety: Population Pharmacokinetics-Based Analysis of Adult Patients With Invasive Fungal Infections [PDF]
, 2017 This population-pharmacokinetics analysis involving adult patients with invasive fungal infections challenges recommended voriconazole dosing regimens. Higher oral than intravenous doses, followed by individualized adjustments based on therapeutic drug ...
Bille, Jacques +6 more
core
Pharmacists' views on the implementation of therapeutic drug monitoring in oncology
Journal of Pharmacy Practice and Research, Volume 55, Issue 5, Page 414-421, October 2025.Abstract Background There is increasing interest in the potential benefit of therapeutic drug monitoring (TDM) in oncology. However, uptake in Australian hospitals is limited. Aim This study sought to explore hospital pharmacists' experiences with TDM in oncology, seeking to determine if they could provide insights into barriers and facilitators to its
Jane E. Carland +3 more
wiley +1 more source