Results 201 to 210 of about 27,626 (220)

Voriconazole Induced Bradycardia

Pediatric Hematology and Oncology, 2013
Voriconazole is a triazole antifungal drug that is used to treat invasive fungal infections, especially aspergillus. Here, we report two children who had severe bradycardia associated with voriconazole at a dose of 12 mg/kg per day. Bradycardia resolved in 24 hours in both after decreasing the dose to 10 mg/kg per day. Heart rates were in normal limits
Tiraje Celkan, Nihal Özdemir, Ayşe Güler Eroğlu, Gülen Tüysüz, Dilek Uludag   +4 more
openaire   +3 more sources

Voriconazole-Susceptible and Voriconazole-Resistant Aspergillus fumigatus Coinfection

American Journal of Respiratory and Critical Care Medicine, 2016
Contains fulltext : 166535.pdf (Publisher’s version ) (Closed access)
Kolwijck, E., Hoeven, H. van der, Sevaux, R.G.L. de, Oever, J. ten, Rijstenberg, L.L., Lee, H.A.L. van der, Zoll, J., Melchers, W.J.G., Verweij, P.E.   +8 more
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Pseudoporphyria induced by voriconazole

Journal of the American Academy of Dermatology, 2005
Pseudoporphyria is an uncommon blistering disorder with clinical and histologic similarities to porphyria cutanea tarda but which lacks urine and serum porphyrin elevations. Pseudoporphyria has been linked with numerous causes including chronic renal failure, ultraviolet radiation, and numerous medications.
Thomas Horn, Misty T. Sharp
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Voriconazole-Induced Neuropathy

Chemotherapy, 2008
<i>Background:</i> Fungal infections are common and life threatening among immunosupressive patients. Rare side effects may occur related to the use of voriconazole, which is the drug of choice in invasive aspergillosis. <i>Patients and Methods:</i> Neuropathy was determined through clinical and electromyographic findings during
Serdar Bedii Omay, Elif Akdogan, Mustafa Yilmaz, Firdevs Aksoy, Ebru Emel Sözen, Iftihar Koksal, Kemalettin Aydin, Vildan Altunayoglu   +7 more
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Voriconazole-Induced Periostitis

New England Journal of Medicine, 2019
Voriconazole-Induced Periostitis A 65-year-old woman with a history of lung transplantation who had been receiving long-term prophylaxis with voriconazole presented with progressive swelling in bot...
Nicole Droz, Joshua Hedrick
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Clinical pharmacokinetics of voriconazole

International Journal of Antimicrobial Agents, 2006
This review presents the published clinical pharmacokinetic data for the antifungal agent voriconazole. Aspects regarding absorption, tissue distribution, elimination and kinetic interactions are also discussed.
Yasmine Nivoix, Dominique Levêque, François Jehl, Raoul Herbrecht   +3 more
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ChemInform Abstract: An Enantioselective Synthesis of Voriconazole.

ChemInform, 2013
A new seven-step sequence to access voriconazole, a clinically used antifungal agent, was developed. The initial catalytic asymmetric cyanosilylation is the key to constructing the consecutive tetra- and trisubstituted stereogenic centers. The fluoropyrimidine unit frequently triggered unexpected side reactions, but careful amendment of the reaction ...
Naoya Kumagai, Keiji Tamura, Makoto Furutachi, Masakatsu Shibasaki   +3 more
openaire   +4 more sources

Voriconazole in the Management of Alternaria Keratitis

Cornea, 2006
To discuss the role of voriconazole in the management of Alternaria keratitis.Case report and literature review.A 69-year-old man with a history of corneal foreign body removal developed a stromal infiltrate 2 months later that did not improve despite topical antibiotics and natamycin.
Hammersmith, KM, Rapuano, CJ, Sivalingam, J, Kang, S, Ozbek, ZEYNEP, Cohen, EJ   +5 more
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Voriconazole: A New Triazole Antifungal

The Annals of Pharmacotherapy, 2000
OBJECTIVE: To review the currently available information on the pharmacology, pharmacokinetics, efficacy, adverse effects, drug interactions, and dosage guidelines of voriconazole. Comparative data for voriconazole and other azole antifungal agents are described where available.
Janelle Sabo, Susan M. Abdel-Rahman
openaire   +3 more sources

Voriconazole

Drugs, 2002
Voriconazole, a broad-spectrum triazole antifungal agent, inhibits the cytochrome P450-dependent enzyme 14-alpha-sterol demethylase, thereby disrupting the fungal membrane and stopping fungal growth. The drug shows excellent in vitro activity against Aspergillus spp., including itraconazole- and amphotericin B-resistant A. fumigatus isolates.
Karen L. Goa, Richard B. R. Muijsers, Lesley J. Scott   +2 more
openaire   +3 more sources