Results 121 to 130 of about 402,414 (297)
Advanced Science, EarlyView.This study established a one‐step method inducing pro‐spermatogonia‐like (activating SOX17) and oogonia‐like (activating SOX17/TFAP2C) cells from porcine pgEpiSCs with a NANOS3‐tdTomato reporter. EGF activates the core PGC program and supports survival; BMP4 further induces NANOS3 and DDX4 expression; IWR1 enhances PGCLC efficiency by suppressing ...
Pengcheng He +14 more
wiley +1 more source
Advanced Science, EarlyView.During kainic acid‐induced epileptogenesis, astrocyte‐associated ATP‐binding cassette transporter A1 (ABCA1) and apolipoprotein E (APOE) responses accompany ectopic neurons and exploratory lipid alterations. In separate cohorts, bexarotene pretreatment and treatment on days 14–21 are associated with fewer ectopic hilar neurons and lower chronic seizure
Lu Chen +10 more
wiley +1 more source
Applied SciencesLaser-induced breakdown spectroscopy (LIBS), limited by matrix effects, self-absorption in complex samples, and ambient atmospheric influences, still requires further improvement in detection sensitivity and signal stability. In this work, the excitation
Yuxia Zhou +5 more
doaj +1 more source
Advanced Science, EarlyView.FLJ20021 interacts with XRCC6 to regulate ADI1 transcription and downstream cellular phenotypes in hUSLFs. Reduced FLJ20021 in POP is associated with lower ADI1, increased apoptosis, senescence, and an ECM‐degrading marker profile. Conversely, FLJ20021 overexpression enhances XRCC6‐dependent ADI1 expression, reduces apoptosis and senescence, and shifts
YanFeng Yang +4 more
wiley +1 more source
Advanced Science, EarlyView.A robust periosteal organoid system enables long‐term expansion while preserving native cellular heterogeneity. These organoids recapitulate functional niche environments, support hematopoietic stem cell maintenance, and attenuate aging‐associated decline ex vivo.
Jia Qing +9 more
wiley +1 more source
Shock Effects on Delta Wing Vortex Breakdown
, 2008 It has been observed that delta wings placed in a transonic freestream can experience a sudden movement of the vortex breakdown location as the angle of incidence is increased.
Fritz, Willy +11 more
core +1 more source
An AI‐Driven Framework for Directed Self‐Assembly Toward Design‐Technology Co‐Optimization
Advanced Science, EarlyView.An artificial intelligence (AI)‐driven closed‐loop framework integrates experiment, three‐dimensional physics‐based simulation, and template design for directed self‐assembly (DSA). Guided by experimental data, AI‐assisted calibration accelerates model optimization, supports morphology prediction, and identifies template windows.
Caiwei Shang +9 more
wiley +1 more source
The dynamics of vortex breakdown
, 2007 Swirling flows with jet-like axial velocities are studied by means of direct numerical simulations for various control parameters. The numerical code solves the low-Mach number approximation of the Navier-Stokes equations in cylindrical coordinates which allows the incorporation of compressible and variable-density effects without the adverse effect of
Vyazmina, Elena +3 more
openaire +1 more source
Supersonic quasi-axisymmetric vortex breakdown [PDF]
, 1991 An extensive computational study of supersonic quasi-axisymmetric vortex breakdown in a configured circular duct is presented. The unsteady, compressible, full Navier-Stokes (NS) equations are used.
Kandil, Osama A. +2 more
core
Advances in Josephson Junction Materials and Processes Toward Practical Quantum Computing
Advanced Science, EarlyView.Emerging materials for quantum computing, including crystalline materials, two‐dimensional van der Waals materials, two‐dimensional electron gas systems, ferromagnets, and unconventional (e.g., d‐wave) superconductors, offer opportunities to engineer next‐generation Josephson junctions.
Hyunseong Kim +11 more
wiley +1 more source