Results 21 to 30 of about 4,278 (263)
AIP Advances, 2019 Recently, numerous studies have been conducted to clarify the effects of the increases in pitching and plunging amplitudes of flapping wings on thrust and lift generation. In the present study, the effects of continuously increasing pitching and plunging
Jun Hu +3 more
doaj +1 more source
Research on the Separation Control Characteristics of Vortex Flap under Different Reynolds Numbers
Hangkong gongcheng jinzhan, 2021 Inspired by birds raising their feathers to control the separation flow, vortex flap has become an approach to control the separation flow over airfoils at high angles of attack.In this paper, the aerodynamic characteristics and physical mechanism of ...
LIN Lihui, YE Kun, YE Zhengyin
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Buildings, 2022 In the present study, multiple-fan active control wind tunnel tests are conducted to investigate the aerodynamic forces on a 5:1 rectangular cylinder in sinusoidal streamwise winds with different angles of attack (AoA).
Bo Wu +5 more
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Reduced-order aerodynamic model of a starting plate with discrete-vortex merging
Frontiers in PhysicsThis study employs potential flow theory with a discrete-vortex method to model the unsteady aerodynamics of a flat plate, with a particular focus on the coupled dynamics of leading-edge and trailing-edge vortices (LEVs and TEVs).
Xi Xia, Lingyun Shangguan
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Aerospace, 2022 The ducted coaxial propeller (DCP) has great application value in eVTOL aircraft because of its high safety, compactness, and low noise. A numerical simulation method for the DCP is established using the sliding mesh technique.
Junjie Wang, Renliang Chen, Jiaxin Lu
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Leading-Edge Vortex Characteristics of Low-Aspect-Ratio Sweptback Plates at Low Reynolds Number
Applied Sciences, 2021 A sweptback angle can directly regulate a leading-edge vortex on various aerodynamic devices as well as on the wings of biological flyers, but the effect of a sweptback angle has not yet been sufficiently investigated.
Jong-Seob Han, Christian Breitsamter
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Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source