Results 41 to 50 of about 318,993 (294)
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Large-Eddy Simulation of Wake Vortex Evolution from Roll-Up to Decay [PDF]
, 2012 The development of an aircraft wake vortex from the roll-up until vortex decay is studied. An aircraft model and the surrounding flow field obtained from high-fidelity Reynolds-averaged Navier-Stokes simulation are swept through a ground-fixed ...
Misaka, Takashi +2 more
core
, 2021 This is the third newsletter of the LIFT research project in Hungarian ...
LIFT consortium
core +1 more source
, 1975 This file unit contains the first volume of The Vortex, a student led publication established on the University of Central Arkansas campus in ...
The Vortex Magazine of Literature and Fine Arts; University of Central Arkansas Department of English
core +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
, 2021 This is the third newsletter of the LIFT research project in French ...
LIFT consortium
core +1 more source
Vortex dynamics and dynamic fluid forces by a flapping butterfly wing
Mechanical Engineering JournalAn elastic moving airfoil is superior to a rigid moving airfoil because the deformation of its shape enables it to generate a larger fluid force. Membrane airfoils, such as butterfly wings, perform well even in low Reynolds number flows and have thus ...
Sei HAISHI, Masaki FUCHIWAKI
doaj +1 more source
Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis
Annals of Clinical and Translational Neurology, EarlyView.Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird +9 more
wiley +1 more source
Active control with dielectric barrier discharge actuators applied to high-lift devices
, 2013 An experimental investigation examined the capability of dielectric barrier discharge (DBD) actuators to control a high-lift device system. Aerodynamic tests investigated the potential of utilising the actuator to control the flap side-edge vortex flow ...
Chappell, S.
core +1 more source
Dynamic release layer mediated optical vortex laser-induced forward transfer
AIP AdvancesOptical vortex laser-induced forward transfer (OV-LIFT) is an innovative approach for printing fine microdots of various materials, including high concentration colloidal solutions and high viscosity inks.
Ken-ichi Yuyama +4 more
doaj +1 more source