Results 41 to 50 of about 332,136 (301)
Numerical simulation analysis of flow around near-wall rotating cylinder
Zhongguo Jianchuan YanjiuObjectivesTo investigate the near-wall rotating cylindrical wake and hydrodynamic characteristics, flow around cylinder at typical gap ratios is investigated.
Zongpeng WANG +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh +11 more
wiley +1 more source
Active control with dielectric barrier discharge actuators applied to high-lift devices
, 2013 An experimental investigation examined the capability of dielectric barrier discharge (DBD) actuators to control a high-lift device system. Aerodynamic tests investigated the potential of utilising the actuator to control the flap side-edge vortex flow ...
Chappell, S.
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Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation
Molecular Oncology, EarlyView.How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim +11 more
wiley +1 more source
Vortex dynamics and dynamic fluid forces by a flapping butterfly wing
Mechanical Engineering JournalAn elastic moving airfoil is superior to a rigid moving airfoil because the deformation of its shape enables it to generate a larger fluid force. Membrane airfoils, such as butterfly wings, perform well even in low Reynolds number flows and have thus ...
Sei HAISHI, Masaki FUCHIWAKI
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, 2021 This is the third newsletter of the LIFT research project in German ...
LIFT consortium
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USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival
Molecular Oncology, EarlyView.CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna +8 more
wiley +1 more source
, 1975 This file unit contains the first volume of The Vortex, a student led publication established on the University of Central Arkansas campus in ...
The Vortex Magazine of Literature and Fine Arts; University of Central Arkansas Department of English
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Dynamic release layer mediated optical vortex laser-induced forward transfer
AIP AdvancesOptical vortex laser-induced forward transfer (OV-LIFT) is an innovative approach for printing fine microdots of various materials, including high concentration colloidal solutions and high viscosity inks.
Ken-ichi Yuyama +4 more
doaj +1 more source
Journal of Marine Science and Engineering, 2019 The deformation of the cylinder has been proved to greatly reduce the fluctuation of lift and the vortex-induced vibration. In this article, a new form of deformation mode for the smooth cylinder is proposed in order to reduce the vortex-induced ...
Chunyu Guo +5 more
doaj +1 more source