Results 41 to 50 of about 441 (221)

Hydraulic Performance of a Francis Turbine with a Variable Draft Tube Guide Vane System to Mitigate Pressure Pulsations

Energies, 2022
The present paper demonstrates a proof-of-concept by introducing a variable guide vane system in the draft tube of a high-head Francis model turbine. The aim is to examine the hydraulic performance of the turbine while mitigating the pressure pulsations ...
Jesline Joy, Mehrdad Raisee, Michel J. Cervantes   +2 more
doaj   +1 more source

Formation of Rotating Vortex Rope in the Francis-99 Draft Tube

IOP Conference Series: Earth and Environmental Science, 2019
The aim of this research is to understand the mechanism(s) of RVR formation duringthe changes in operating condition from the Best Efficiency Point (BEP) to Part Load (PL).
N Sotoudeh, R Maddahian, M J Cervantes
openaire   +1 more source

Neuroprotective Effects of Time‐Restricted Feeding Combined With Different Protein Sources in MPTP‐Induced Parkinson's Disease Mice Model and Its Modulatory Impact on Gut Microbiota Metabolism

Advanced Science, EarlyView.
Time‐restricted feeding (TRF) exerts protein‐dependent neuroprotective effects in an MPTP‐induced Parkinson's disease model. In casein‐fed mice, TRF improves gut barrier integrity and reduces neuroinflammation, possibly via modulation of Allobaculum and BCAAs.
Ting Li, Jian Wu, Sheng‐Yang Zhou, Ming‐An Li, Li‐Ping Zhao, Ao Wang, Yi‐Zhi Song, Wen‐Yan Huang, Lu‐Lu Tan, Chen‐Meng Qiao, Wei‐Jiang Zhao, Chun Cui, Yan‐Qin Shen   +12 more
wiley   +1 more source

Phosphatidic Acid‐TRIM59‐Olig2 Signaling Couples Metabolic Dysfunction to Myelination Failure in PWMI

Advanced Science, EarlyView.
PA accumulates after hypoxic‐ischemic injury and stabilizes the E3 ligase TRIM59 in OPCs. Stabilized TRIM59 enhances ubiquitination and degradation of Olig2, blocking differentiation and causing hypomyelination in PWMI. Modulating PA synthesis restores Olig2 levels, improves myelination, and ameliorates behavioral deficits, defining a metabolically ...
Xinyu Li, Yanan Liu, Meng Zhang, Yiwei Liu, Meiting Liu, Kaishen Zhu, Zhian Liu, Chao Ren, Ruiqin Yao   +8 more
wiley   +1 more source

Leveraging Artificial Intelligence and Large Language Models for Cancer Immunotherapy

Advanced Science, EarlyView.
Cancer immunotherapy faces challenges in predicting treatment responses and understanding resistance mechanisms. Artificial intelligence (AI) and machine learning (ML) offer powerful solutions for cancer immunotherapy in patient stratification, biomarker discovery, treatment strategy optimization, and foundation model development.
Xinchao Wu, Mengtao Sun, Lusheng Li, Jieqiong Wang, Shibiao Wan   +4 more
wiley   +1 more source

Artificial Intelligence for Bone: Theory, Methods, and Applications

Advanced Intelligent Discovery, EarlyView.
Advances in artificial intelligence (AI) offer the potential to improve bone research. The current review explores the contributions of AI to pathological study, biomarker discovery, drug design, and clinical diagnosis and prognosis of bone diseases. We envision that AI‐driven methodologies will enable identifying novel targets for drugs discovery. The
Dongfeng Yuan, Haicang Zhang, Liping Tong, Di Chen   +3 more
wiley   +1 more source

The numerical simulation of the rope vortex creation and the possibilities of its control

Journal of Physics: Conference Series, 2021
Abstract The rope vortex is a phenomena which can be observed in many hydraulic machines, especially turbines and pump–turbines. Its creation is based on a non uniform velocity profile characterized by high value of the circumferential component.
P Szulc, A Machalski, J Skrzypacz, D Blonski   +3 more
openaire   +1 more source

Deep Learning‐Assisted Coherent Raman Scattering Microscopy

Advanced Intelligent Discovery, EarlyView.
The analytical capabilities of coherent Raman scattering microscopy are augmented through deep learning integration. This synergistic paradigm improves fundamental performance via denoising, deconvolution, and hyperspectral unmixing. Concurrently, it enhances downstream image analysis including subcellular localization, virtual staining, and clinical ...
Jianlin Liu, Rujia Liu, Xinyan Zhang, Xun Chen, Shuhua Yue   +4 more
wiley   +1 more source

Innovative Device to Control Self-Induced Instabilities Associated with the Swirling Flow from the Discharge Cone of Hydraulic Turbines

Actuators
In our previous research work, we investigated different methods to mitigate the vortex rope that appears in the draft tube of a Francis turbine when it operates at off-design operating points.
Constantin Tănasă, Adrian Ciprian Stuparu, Alin Bosioc, Cristina Terteci, George Belgiu, Sorin Nanu   +5 more
doaj   +1 more source

Pengujian Turbin Air Pusaran Gravitasi dengan Variasi Overlap Ratio Rotor

Metal: Jurnal Sistem Mekanik dan Termal, 2022
The gravitational water vortex turbine is a turbine system that can convert the energy from artificial water vortex by means of the drained water through the basin outlet to the kinetic energy of rotor rotation.
Muhammad Luthfi, Meri Rahmi, Rachmatullah -   +2 more
doaj   +1 more source