Results 41 to 50 of about 418 (177)
Advanced Science, EarlyView.TIPE1m NPs nanoparticles restore TIPE1 expression, promote RAB7A ubiquitination and degradation, suppress autophagic flux, and resensitize paclitaxel‐resistant triple‐negative breast cancer to therapy. ABSTRACT Acquired paclitaxel (PTX) resistance remains a major obstacle in triple‐negative breast cancer (TNBC) treatment.
Wei Hu +9 more
wiley +1 more source
Applied SciencesPump-turbines are critical for maintaining power grid stability, but they frequently suffer from flow instabilities induced by cavitation due to frequent operating condition changes.
Yanhao Li, Lei Chen, Jianwen Xu, An Yu
doaj +1 more source
AIChE Journal, EarlyView.Abstract Transformer‐based molecular models pretrained on SMILES strings demonstrate strong performance in property prediction. However, these model often lack explicit integration of molecular surface charge distributions that govern intermolecular interactions such as hydrogen bonding and polarity.
Tae Hyun Kim +2 more
wiley +1 more source
Formation of Rotating Vortex Rope in the Francis-99 Draft Tube
IOP Conference Series: Earth and Environmental Science, 2019 The aim of this research is to understand the mechanism(s) of RVR formation duringthe changes in operating condition from the Best Efficiency Point (BEP) to Part Load (PL).
N Sotoudeh, R Maddahian, M J Cervantes
openaire +1 more source
Data‐Guided Photocatalysis: Supervised Machine Learning in Water Splitting and CO2 Conversion
Advanced Intelligent Discovery, EarlyView.This review highlights recent advances in supervised machine learning (ML) for photocatalysis, emphasizing methods to optimize photocatalyst properties and design materials for solar‐driven water splitting and CO2 reduction. Key applications, challenges, and future directions are discussed, offering a practical framework for integrating ML into the ...
Paul Rossener Regonia +1 more
wiley +1 more source
Energies, 2022 The present paper demonstrates a proof-of-concept by introducing a variable guide vane system in the draft tube of a high-head Francis model turbine. The aim is to examine the hydraulic performance of the turbine while mitigating the pressure pulsations ...
Jesline Joy +2 more
doaj +1 more source
Harnessing Machine Learning to Understand and Design Disordered Solids
Advanced Intelligent Discovery, EarlyView.This review maps the dynamic evolution of machine learning in disordered solids, from structural representations to generative modeling. It explores how deep learning and model explainability transform property prediction into profound physical insight.
Muchen Wang, Yue Fan
wiley +1 more source
AI‐Driven Cancer Multi‐Omics: A Review From the Data Pipeline Perspective
Advanced Intelligent Discovery, EarlyView.The exponential growth of cancer multi‐omics data brings opportunities and challenges for precision oncology. This review systematically examines AI's role in addressing these challenges, covering generative models, integration architectures, Explainable AI for clinical trust, clinical applications, and key directions for clinical translation.
Shilong Liu, Shunxiang Li, Kun Qian
wiley +1 more source
Advanced Intelligent Discovery, EarlyView.Matrix‐assisted laser desorption/ionization imaging‐based identification of reliable small molecule markers across heterogeneous glioblastoma cohorts is challenging with intensity‐only methods. We present spatially informed feature selection (SIFS), a spatially informed framework that prioritizes molecules consistently colocalizing with histopathology.
Shad A. Mohammed +15 more
wiley +1 more source
Energy distribution and chaotic pressure pulsation analysis of vortex ropes in Francis-99
Engineering Applications of Computational Fluid MechanicsFrancis turbines, essential for stability in diverse operating conditions and variable-speed scenarios, encounter efficiency-compromising vortex rope formations in the draft tube, leading to substantial pressure fluctuations.
Puxi Li +5 more
doaj +1 more source