Results 91 to 100 of about 254,596 (292)

A Versatile‐Designable Framework for Active and Programmable Shape‐Morphing Soft Matter Systems: From Inverse Design to Closed‐Loop Control

open access: yesAdvanced Science, EarlyView.
A versatile framework integrates addressable electrothermal actuation and strain‐constraint mechanisms to construct programmable shape‐morphing soft matter systems. By combining an analytical inverse design strategy for high‐fidelity 3D surface reconstruction with deep learning‐based closed‐loop control, this approach enables zero‐energy shape locking,
Kai Liu   +5 more
wiley   +1 more source

Effects of Damping and Reynolds Number on Vortex-Induced Vibrations [PDF]

open access: yes, 2007
Vortex-induced vibrations have been studied experimentally with emphasis on damping and Reynolds number effects. Our system was an elastically-mounted rigid circular cylinder, free to oscillate only transverse to the flow direction, with very low ...
Klamo, Joseph Thomas
core   +1 more source

Emergent Spinning and Orbital Motion in Clustered Wind‐Assisted Flyers

open access: yesAdvanced Science, EarlyView.
Inspired by natural snowflake geometries, paper‐cut flyers exhibit geometry‐defined spinning and orbital motions during cluster formation in a wind tunnel. Collective flights of multiple paperflakes reveal dynamic clustering, fragmentation, and continuously evolving spin behaviors.
Bingnan Zhou   +7 more
wiley   +1 more source

Strategy of Triple‐Gradient in Binary Pixels for Flexible Pressure Sensing with High Sensitivity and Wide‐Range Linearity

open access: yesAdvanced Science, EarlyView.
A flexible pressure sensor with triple‐gradient design of conductivity, modulus, and dimension in binary micro‐dome pixels is proposed. Based on precisely‐designed CNT/PDMS matrix, the device exhibits a linear sensitivity of 974.1 kPa−1 across range up to 1.8 MPa (R2 > 0.99), offering an effective strategy for potential applications in healthcare ...
Yifan Liu   +9 more
wiley   +1 more source

A Phosphorylation‐Induced Micellization Switch in the Low‐Complexity Domain of TDP‐43

open access: yesAdvanced Science, EarlyView.
Phosphorylation of TAR DNA‐binding protein's 43 kDa (TDP‐43) low‐complexity domain by casein kinase 1 delta (CK1δ) acts as a molecular switch, redirecting its self‐assembly from macroscopic phase separation toward finite‐sized, spherical block‐copolymer micelles of ∼30 nm.
Rodrigo F. Dillenburg   +16 more
wiley   +1 more source

Numerical optimization of microfluidic vortex shedding for genome editing T cells with Cas9. [PDF]

open access: yesSci Rep, 2021
Jarrell JA   +7 more
europepmc   +1 more source

Molecular Dynamics‐Guided Sterol Engineering of mRNA‐Lipid Nanoparticles Reprograms Biodistribution and Enhances Spleen‐Selective Immunity

open access: yesAdvanced Science, EarlyView.
Sterol engineering enables precise control of mRNA lipid nanoparticles by tuning membrane organization. Replacing cholesterol with bile acid‐derived sterols redirects protein expression from the liver to the spleen. Notably, CA‐20 LNP enhances antigen‐specific immune responses while exhibiting a favorable safety profile, highlighting sterols as a ...
Sanghyuk Jeon   +27 more
wiley   +1 more source

Transition in vortex wakes of flow around an elliptic cylinder

open access: yesArchives of Mechanics
Transition in the wake flow around an elliptic cylinder was numerically investigated at Reynolds numbers (Re) ranging from 3 to 200. The cylinder axis ratio (AR) varies from 0.125 to 8, while its angle of attack (AoA) was examined at 30°, 60°, and 90 ...
V.L. Nguyen, V.D. Duong, L.H. Duong
doaj   +1 more source

Spatiotemporally Ultrasound‐Controlled Nanoparticles Reprogramming Immunostimulatory Antigen‐Presenting Cancer‐Associated Fibroblasts to Enhance Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
We developed an ultrasound‐controlled biomimetic nanoplatform, mRNA/V@M NPs, to co‐deliver CD74 mRNA and V‐9302 for fibrotic TNBC therapy. CD74 mRNA reprograms myCAFs into antigen‐presenting apCAF cells through the CD74‐MHC II pathway, while V‐9302 induces ICD and activates MHC I‐CD8+ T cell immunity.
Chen Ai   +9 more
wiley   +1 more source

Control of vortex shedding at moderate Reynolds numbers

open access: yes, 2002
The suppression method of vortex shedding from a circular cylinder has been studied experimentally in the Reynolds number range from 300 to 1600. The test is performed in a water channel. The model cylinder is 1 cm in diameter and 38 cm in length.
Shao CP(邵传平)   +3 more
core   +1 more source

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