Results 121 to 130 of about 48,395 (233)

Unraveling Chronic Pain: From Mechanisms and Risks to Diagnosis and Treatment

MedComm, Volume 7, Issue 4, April 2026.
Chronic pain arises through distinct molecular pathways categorized into nociceptive, neuropathic, and nociplastic types. Nociceptive pain begins with TRP channel activation in peripheral nociceptors, signaling via Aδ‐ and C‐fibers through the spinal dorsal horn and spinothalamic tracts to the brain, regulated by descending inhibition and involving ...
Xiaofeng Dai, Chongxiang Wang, Ping Jiang, Xiaopeng Mei   +3 more
wiley   +1 more source

Gray matter structural correlates of fatigue in multiple sclerosis [PDF]

, 2016
We aimed to assess whether frontal cortex-striatum-thalamus (FCST) pathway or other grey matter (GM) structures are associated with longitudinal patterns of fatigue, namely reversible (RF) versus sustained fatigue (SF).
Nazeri, Aria
core   +1 more source

Deep Learning Reconstruction for 129Xe Diffusion‐Weighted MRI Enables Use of Natural Abundant Xenon and Improved Image Acceleration

Magnetic Resonance in Medicine, Volume 95, Issue 4, Page 2214-2222, April 2026.
ABSTRACT Purpose (i) To assess whether 129Xe apparent diffusion coefficient (ADC) and diffusive length scale (LmD) metrics are quantitatively preserved with deep learning (DL) accelerated acquisition and reconstruction and (ii) to evaluate the feasibility of 129Xe diffusion weighted imaging with natural‐abundance xenon at increased acceleration factors.
Rajagopalan Sundaresan, Guilhem J. Collier, Neil J. Stewart, Sudhanya Chatterjee, Ramesh Venkatesan, Jan Wolber, Jim M. Wild   +6 more
wiley   +1 more source

Longitudinal 3D‐DCE MRI Assessment of Placental Perfusion Under Reduced Uterine Perfusion Pressure in Pregnant Rats

NMR in Biomedicine, Volume 39, Issue 4, April 2026.
This first application of longitudinal 3D‐DCE MRI in the RUPP model demonstrated acute perfusion deficits after RUPP that resolved rapidly with advancing gestation, consistent with the adaptive placental responses to reduced uterine blood flow. ABSTRACT Placental insufficiency is a major cause of preeclampsia and fetal growth restriction.
Fatimah M. Al Darwish, Caren M. van Kammen, Fieke Terstappen, Lindy K. Alles, Raymond M. Schiffelers, A. Titia Lely, Gustav J. Strijkers, Bram F. Coolen   +7 more
wiley   +1 more source

Altered Brain Tissue Volumes With Valproate Treatment for Schizophrenia

Journal of the Royal Society of New Zealand, Volume 56, Issue 2, April 2026.
Schizophrenia is a debilitating psychiatric condition that affects ≈0.5% of the global population. Some people with schizophrenia do not respond to first‐line antipsychotics and are prescribed clozapine; this is termed treatment‐resistant schizophrenia (TRS).
Thomas Cawood, Olivia K. Harrison, Meghan McIlwain, Robert R. Kydd, Bruce R. Russell   +4 more
wiley   +1 more source

Why ruminators won't stop: the structural and resting state correlates of rumination and its relation to depression [PDF]

, 2012
De Raedt, Rudi, Gallinat, Jürgen, Kühn, Simone, Vanderhasselt, Marie-Anne   +3 more
core   +1 more source

Brain structure in pediatric Tourette syndrome [PDF]

, 2017
Previous studies of brain structure in Tourette syndrome (TS) have produced mixed results, and most had modest sample sizes. In the present multicenter study, we used structural magnetic resonance imaging (MRI) to compare 103 children and adolescents ...
Black, K. J, Greene, D. J, Koller, J. M, Schlaggar, B. L, The Tourette Association of America Neuroimaging Consortium, Williams III, A. C   +5 more
core   +2 more sources

Mapping brain change longitudinally: physical activity intervention reshapes structural alterations and functional connectivity in Alzheimer's disease

Alzheimer's &Dementia: Translational Research &Clinical Interventions, Volume 12, Issue 2, April/June 2026.
Abstract INTRODUCTION Physical activity is a promising non‐pharmacological approach to support brain health. Although prior studies suggest cognitive benefits, it remains unclear how exercise alters brain structure and connectivity on the Alzheimer's disease (AD) continuum and whether such neural changes translate to functional improvements. This study
Ravi Dadsena, Ana S. Costa, Shari David, Luisa Haberl, Jörg B. Schulz, Kathrin Reetz, Alexa Haeger   +6 more
wiley   +1 more source

Annual Research Review: Neural mechanisms of eating disorders in youth – from current theory and findings to future directions

Journal of Child Psychology and Psychiatry, Volume 67, Issue 4, Page 444-466, April 2026.
Eating disorders are prevalent and profoundly debilitating psychiatric conditions with multifactorial etiology that frequently manifest during adolescence. This developmental stage is characterized by significant neurostructural and neurofunctional change, which may create a context conducive to the emergence of eating pathology.
Kelsey Hagan, E. Caitlin Lloyd, Sasha Gorrell   +2 more
wiley   +1 more source

Study of the cerebral alterations of schizophrenia through meta-analysis by neuroimaging [PDF]

, 2019
Treball Final de Grau en Psicologia. Codi: PS1048. Curs: 2018/2019.Schizophrenia is a chronic mental disorder, which can cause brain and functional abnormalities. This pathology affects 1% of the world population.
Merzouk Belmihoub, Soumaya
core