Results 41 to 50 of about 22,955 (198)

In Situ Profiling of Nanoscale Strains Uncovers Mechano‐Architectural Predictors of Aging and Osteoarthritis Emergence

Advanced Science, EarlyView.
In situ mechanical loading of osteoarthritis‐prone murine knee joints reveals that spatial alterations in subchondral plate microarchitecture precede cartilage loss and promote a shift from coordinated epiphyseal strain dissipation in healthy joints to focal subchondral strain concentration in osteoarthritis‐prone joints.
Aikta Sharma, Lucinda A. E. Evans, Lucie E. Bourne, Jishizhan Chen, Alissa L. Parmenter, Joseph Brunet, Kamel Madi, Sebastian Marussi, Andrew A. Pitsillides, Peter D. Lee, Katherine A. Staines   +10 more
wiley   +1 more source

Accelerated Brain Atrophy in Epilepsy: A Prospective Population‐Based Study

Annals of Neurology, EarlyView.
Objective Previous longitudinal neuroimaging studies suggest that epilepsy is a progressive disorder. To date, these findings have relied largely on populations from tertiary centers, resulting in ascertainment bias, as severely affected individuals are more likely to be rescanned.
Marian Galovic, Rebecca S. N. Liu, Alex D. Everitt, Robert Terziev, Louis Lemieux, Matthias J. Koepp, John S. Duncan   +6 more
wiley   +1 more source

MRI Correlates of Parkinson’s Disease Progression: A Voxel Based Morphometry Study

Parkinson's Disease, 2015
We investigated structural brain differences between a group of early-mild PD patients at different phases of the disease and healthy subjects using voxel-based morphometry (VBM).
Valentina Fioravanti, Francesca Benuzzi, Luca Codeluppi, Sara Contardi, Francesco Cavallieri, Paolo Nichelli, Franco Valzania   +6 more
doaj   +1 more source

Cortical Thickness and White Matter Surface Morphology in Tourette Syndrome: A Cohort Study

Annals of Neurology, EarlyView.
Objective To examine cortical thickness and white matter surface morphology in a large sample of individuals with Tourette syndrome (TS) and neurotypical controls across the lifespan, and to assess associations with symptom severity, comorbidities, and medication use.
Sahar Delavari, Adam C. Frank, Ravi Bansal, Flora M. Vaccarino, Robert A. King, Paul Lombroso, Lawrence Scahill, James F. Leckman, Bradley S. Peterson   +8 more
wiley   +1 more source

Diffuse Decreased Gray Matter in Patients with Idiopathic Craniocervical Dystonia: a Voxel-Based Morphometry Study

Frontiers in Neurology, 2015
Background: Recent studies have addressed the role of structures other than the basal ganglia in the pathophysiology of craniocervical dystonia. Neuroimaging studies have attempted to identify structural abnormalities in craniocervical dystonia but a ...
Camila Callegari Piccinin, Luiza Gonzaga Piovesana, Maria Cristina Arci Santos, Rachel Paes Guimaraes, Brunno Machado De Campos, Thiago Junqueira Rezende, Lidiane eCampos, Fabio Rossi Torres, Augusto eAmato-Filho, Marcondes C. França Jr, Marcondes C. França Jr, Iscia eLopes-Cendes, Fernando eCendes, Fernando eCendes, Anelyssa eD'Abreu, Anelyssa eD'Abreu   +15 more
doaj   +1 more source

Investigating structural brain changes of dehydration using voxel-based morphometry. [PDF]

PLoS ONE, 2012
Dehydration can affect the volume of brain structures, which might imply a confound in volumetric and morphometric studies of normal or diseased brain.
Daniel-Paolo Streitbürger, Harald E Möller, Marc Tittgemeyer, Margret Hund-Georgiadis, Matthias L Schroeter, Karsten Mueller   +5 more
doaj   +1 more source

Multi-site voxel-based morphometry — Not quite there yet

NeuroImage, 2011
Voxel-based morphometry (VBM) is a widely applied method in computational neurosciences but it is currently recommended to compare only data collected at a single MRI scanner. Multi-site VBM would be a desirable approach to increase group size and, thus, statistical power. We aimed to assess if multi-site VBM is feasible on similar hardware and compare
Niels K. Focke, Gunther Helms, S. Kaspar, C. Diederich, V. Tóth, Peter Dechent, A. Mohr, Walter Paulus   +7 more
openaire   +4 more sources

Preoperative limbic cortical thinning in mesial temporal lobe epilepsy surgical candidates is associated with pre‐existing and de novo postoperative depression

Epileptic Disorders, EarlyView.
Abstract Objective Depression is common in mesial temporal lobe epilepsy (mTLE), but its neuroanatomical basis—and overlap with major depressive disorder (MDD)—remains poorly defined. We investigated whether the cortical and subcortical alterations reported in MDD are also present in mTLE and leveraged the frequent occurrence of depression after ...
Philip Fink‐Jensen, Brice Ozenne, Ane Kloster, Bo Jespersen, Kirsten Vinter, Guido Rubboli, Martin Balslev Jørgensen, Sandor Beniczky, Melanie Ganz, Lars Hageman Pinborg   +9 more
wiley   +1 more source

Neuroanatomical Insights: Convergence and Divergence of Tinnitus with Normal or Mild Hearing Loss

Biomedicines
Objectives: To explore the neuroanatomical abnormalities in idiopathic tinnitus patients by voxel-based morphometry (VBM) and surface-based morphometry (SBM) techniques. To elucidate the central plasticity in tinnitus patients with normal or mild hearing
Xingqian Shen, Jing Li, Hui Pan, Linlin Wang, Yangming Leng, Hongjun Xiao, Bo Liu, Wenliang Fan   +7 more
doaj   +1 more source

Voxel‐Based Morphometry and Voxel‐Based Relaxometry in Parkinsonian Variant of Multiple System Atrophy

Journal of Neuroimaging, 2010
ABSTRACTBACKGROUND AND PURPOSE Multiple system atrophy (MSA) is a progressive neurodegenerative disorder divided into a parkinsonian (MSA‐P) and a cerebellar variant. The purpose of this study was to assess regional brain atrophy and iron content using Voxel‐based morphometry (VBM) and Voxel‐based relaxometry (VBR) respectively, in MSA‐P. METHODS Using
Tzarouchi, L. C., Astrakas, L. G., Konitsiotis, S. T., Tsouli, S., Margariti, P. N., Zikou, A. K., Argyropoulou, M. I.   +6 more
openaire   +4 more sources