Results 71 to 80 of about 22,955 (198)

Key Interventions in Friedreich's Ataxia and Their Impact on Patient Outcomes: A Systematic Review

Movement Disorders, EarlyView.
Abstract Friedreich's ataxia (FA) is a rare neurodegenerative disease with multisystemic symptoms that requires multidisciplinary care. This systematic review summarizes available pharmacological and nonpharmacological interventions, their outcomes, and alignment with patient‐centered care domains, as well as their impact on these domains.
Dorota Sarwinska, Maresa Buchholz, Audrey Iskandar, Marcus Grobe‐Einsler, Thomas Klockgether, Jennifer Faber, Bernhard Michalowsky   +6 more
wiley   +1 more source

Brain morphological alternation in chronic pain patients with neuropathic characteristics

Molecular Pain, 2016
Background Neuropathic characteristics are highly involved in the development of chronic pain both physically and psychologically. However, little is known about the relationship between neuropathic characteristics and brain morphological alteration ...
Satomi Sugimine MD, Yuichi Ogino MD, PhD, Hiroaki Kawamichi PhD, Hideaki Obata MD, PhD, Shigeru Saito MD, PhD   +4 more
doaj   +1 more source

Early Longitudinal Brain Network Changes in Huntington's Disease Before Clinical Motor Onset

Movement Disorders, EarlyView.
Abstract Background Longitudinal studies of seed‐based functional connectivity (SBFC) in young adult Huntington's disease gene‐expanded (HDGE) individuals are rare, and none, to our knowledge, have examined adult cohorts decades from predicted clinical motor diagnosis.
Michela Leocadi, Nicola Z. Hobbs, Mena Farag, Michael J. Murphy, Kate Fayer, Olivia Thackeray, Harry Knights, James B. Rowe, Trevor W. Robbins, Barbara J. Sahakian, Geraint Rees, Rachael I. Scahill, Sarah J. Tabrizi, Christelle Langley   +13 more
wiley   +1 more source

Grey and white matter volumes in early childhood: A comparison of voxel-based morphometry pipelines

Developmental Cognitive Neuroscience, 2020
Early childhood is an important period of sensory, motor, cognitive and socio-emotional maturation, yet relatively little is known about the brain changes specific to this period.
Logan Haynes, Amanda Ip, Ivy Y.K. Cho, Dennis Dimond, Christiane S. Rohr, Mercedes Bagshawe, Deborah Dewey, Catherine Lebel, Signe Bray   +8 more
doaj   +1 more source

Structural Brain and Spinal Cord Signature of Spinocerebellar Ataxia 27B: A Multisite MRI‐Based Study

Movement Disorders, EarlyView.
Abstract Background SCA27B is a recently described ataxia, the precise anatomical basis of which remains unclear. Objective The goal was to characterize the structural brain and spinal cord magnetic resonance imaging (MRI) signature of spinocerebellar ataxia 27B (SCA27B) using multimodal quantitative imaging.
Nadson Bruno Serra Santos, Camila Caroso Lobo, Thiago Junqueira Ribeiro Rezende, Alberto Rolim Muro Martinez, Luiza A. Corazza, Luiz Eduardo Novis, Orlando Graziani Povoas Barsottini, José Luiz Pedroso, Pedro José Tomaselli, Wilson Marques Jr, Antônio Carlos dos Santos, David Pellerin, Bernard Brais, Roberta La Piana, Jemimah Harding, Penny Snell, Paul J. Lockhart, David Szmulewicz, Ian H. Harding, Marcondes Cavalcante França Jr   +19 more
wiley   +1 more source

Brain morphometry in transient global amnesia: a triangulated analysis approach [PDF]

Dementia & Neuropsychologia
Transient global amnesia (TGA) is a rare, temporary, sudden-onset disturbance in anterograde episodic memory with unclear pathophysiology. Previous brain volumetric analysis in TGA patients showed varied results. Objective: To explore brain morphometry,
Micaela Anahi Hernández, Hernán Chaves, Ricardo Francisco Allegri, Ismael Luis Calandri   +3 more
doaj   +1 more source

Use of the voxel-based morphometry method in the diagnosis of dementia of the Alzheimer type

Обозрение психиатрии и медицинской психологии имени В.М. Бехтерева, 2018
In recent years, new data in neuroanatomy of patients with various neurodegenerative diseases, including Alzheimer’s disease, were obtained usingmagnetic resonance morphometry.
E. . Andreev, N. . Ananieva, N. . Zalutskaya, I. A. Beltceva, N. . Neznanov   +4 more
doaj  

Differences in cerebral structure among patients with amnestic mild cognitive impairment and patients with Alzheimer’s disease

Frontiers in Aging Neuroscience
BackgroundBrain has been shown to undergo progressive atrophy in patients with Alzheimer’s disease (AD); however, more evidence is needed to elucidate how the brain structure changes during the progression to AD.
Xiaorui Cui, Mingpeng Li, Guanxiong Lei, Guanxiong Lei, Jie Wang, Jialin Pan, Sheng Zhu, Tao Wu, Liangyu Zou, Jianhui Yan   +9 more
doaj   +1 more source

Speech Recognition Deficits in Presbyacusis: Links to Cortical Structural and Functional Alterations

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective To characterize speech recognition in presbyacusis and its associated neurophysiological and cortical structural features, and to explore structure‐function‐behavior relationships within the presbyacusis phenotype. Methods Thirty elderly patients with presbyacusis(HI) and thirty‐three healthy young controls(NH) completed a behavioral
Xiao‐Qian Ren, Lan Lan, Xiao‐Long Li, Xiang‐Bing Bian, Jin Li, Lan Yu, Dan‐Yang Li, Xin Lou, Qiu‐Ju Wang   +8 more
wiley   +1 more source

Significance of voxel-based morphometry in studying mild cognitive impairments

Анналы клинической и экспериментальной неврологии, 2017
Cognitive impairments are an important medical and socialproblem associated with a high prevalence of this disease in thepopulation. 46% of patients develop dementia within 5 years afterthe diagnosis of mild cognitive impairments (MCIs ...
A. I. Damulina, R. N. Konovalov, A. S. Kadykov   +2 more
doaj   +1 more source