Results 31 to 40 of about 6,172 (266)

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Il viaggio al femminile : le donne polacche in Italiatra l’Ottocento e il Novecento

open access: yesItalies, 2014
Le nombre important d’étudiants inscrits dans les universités italiennes montre que les Polonais ont toujours été un peuple de voyageurs. Mais, jusqu’à la fin du XVIIIe siècle, le voyage demeure une activité masculine.
Anna Tylusińska-Kowalska
doaj   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim   +4 more
wiley   +1 more source

Post-mémoire et Histoire à partir d’une revisitation d’expériences exiliques

open access: yesCarnets, 2017
When it comes to approaching Voyages en postcolonies, the question that can be asked is precisely what role the travel narrative plays, witness that it is of a time and postcolonial experience lived by Stora.
Fátima Outeirinho
doaj   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

open access: yesFEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia   +9 more
wiley   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

open access: yesFEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain   +11 more
wiley   +1 more source

Analogies et contrastes entre l'expédition d'Egypte et le voyage d'Humboldt et Bonpland

open access: yesHistória, Ciências, Saúde: Manguinhos, 2001
Alexandre de Humbodlt et Aimé Bonpland avaient prévu de se joindre aux savants de l'expédition française en Egypte. Ayant dû renoncer à ce projet et ayant obtenu l'autorisation du gouvernement espagnol, il réalisèrent leur voyage en Amérique Latine.
Drouin Jean-Marc
doaj  

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