Results 181 to 190 of about 12,722 (195)
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A general synthetic method toward uridylylated picornavirus VPg proteins
Journal of Peptide Science, 2013Small proteins called viral protein genome‐linked (VPg), attached to the 5′‐end of the viral RNA genome are found as common structure in the large family of picornaviruses. The replication of these viruses is primed by this VPg protein linked to a single uridylyl residue.
Gerbrand J, van der Heden van Noort +4 more
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Characterising Chordal Contact $$B_0$$-VPG Graphs
2018A graph G is a \(B_0\)-VPG graph if it is the vertex intersection graph of horizontal and vertical paths on a grid. A graph G is a contact \(B_0\)-VPG graph if the vertices can be represented by interiorly disjoint horizontal or vertical paths on a grid and two vertices are adjacent if and only if the corresponding paths touch.
Flavia Bonomo +3 more
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Biochemistry (Moscow), 2002
VPg unlinkase is an unusual eukaryotic enzyme that catalyzes hydrolysis of the phosphodiester bond between residues of the unique tyrosine of VPg (viral protein genome-linked) and the 5;-terminal uridylic acid of picornavirus RNA. Cellular targets of the VPg unlinking enzyme are yet unknown.
A Yu, Gulevich +2 more
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VPg unlinkase is an unusual eukaryotic enzyme that catalyzes hydrolysis of the phosphodiester bond between residues of the unique tyrosine of VPg (viral protein genome-linked) and the 5;-terminal uridylic acid of picornavirus RNA. Cellular targets of the VPg unlinking enzyme are yet unknown.
A Yu, Gulevich +2 more
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Cell, 1982
Anti-VPg antibodies inhibited host-factor-dependent RNA synthesis by the poliovirus replicase but not oligo(U)-primed synthesis, implicating VPg in the de novo initiation of replicase products. Complexes of VPg-related polypeptide and newly made RNA could be immunoprecipitated by anti-VPg antibody from the host-factor-stimulated products of the ...
M H, Baron, D, Baltimore
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Anti-VPg antibodies inhibited host-factor-dependent RNA synthesis by the poliovirus replicase but not oligo(U)-primed synthesis, implicating VPg in the de novo initiation of replicase products. Complexes of VPg-related polypeptide and newly made RNA could be immunoprecipitated by anti-VPg antibody from the host-factor-stimulated products of the ...
M H, Baron, D, Baltimore
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Tweede congres lectoraat PsychoGeriatrie en VPG
Denkbeeld, 2007Op donderdag 7 juni 2007 organiseert het lectoraat PsychoGeriatrie van de Haagse Hogeschool, WoonZorgcentra Haaglanden en Zorggroep Florence zijn tweede congres. Dit congres, dat plaatsvindt in samenwerking met de Vereniging voor Psychogeriatrie en Alzheimer Nederland, heeft als titel ‘Werken in de psychogeriatrie is een vak apart!?’ en wil het ...
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Simulation of Vehicle Ride Comfort Based on VPG
2010 Third International Conference on Intelligent Networks and Intelligent Systems, 2010Virtual proving ground (VPG) technology is applied to simulate vehicle ride comfort. The multi-body dynamics model for vehicle virtual simulation and random road surface are established under VPG. The body acceleration time-domain curves and frequency-domain power spectrums are obtained by LS-DYNA. Total weighted acceleration of vehicle ride comfort is
Ke Chen, Jie Gao
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Formation and working mechanism of the picornavirus VPg uridylylation complex
Current Opinion in Virology, 2014The initiation of picornavirus replication is featured by the uridylylation of viral protein genome-linked (VPg). In this process, viral RNA-dependent RNA polymerase (RdRp) catalyzes two uridine monophosphate (UMP) molecules to the hydroxyl group of the third tyrosine residue of VPg.
Yuna, Sun, Yu, Guo, Zhiyong, Lou
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De VPG op weg naar een nieuwe visie
Denkbeeld, 2009Op 12 oktober hield de VPG een bijkomst met mensen uit het veld over de visie De kracht van het persoonlijke (zie het vorige nummer van DENKBEELD). VPG-voorzitter Paul Geelen blikt terug op de conferentie en schetst de plannen van de vereniging voor het komende jaar.
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Characterisation of the Mechanism of Norovirus VPg-Nucleotidylylation
Noroviruses, which belong to the *Caliciviridae* family, have a substantial yearly impact on the global economy of about $60 billion and cause about 200,000 deaths per annum in children under the age of 5. Despite causing most cases of viral gastroenteritis, noroviruses remain poorly characterised compared to other viruses.openaire +1 more source