Results 131 to 140 of about 7,193 (199)

Expression of genes involved in neurodegenerative diseases in yeast species subjected to stress [PDF]

, 2018
Traballo fin de mestrado (UDC.CIE). Neurociencia. Curso 2017/2018[Resumo] As enfermidades neurodexenerativas causadas polos factores ambientais, teñen unha alta incidencia na poboación humana actual. Os metais pesados como o cadmio afectan a expresión de
Peixoto Rodríguez, Alejandro
core   +1 more source

Identification of potential cell death-related biomarkers for diagnosis and treatment of osteoporosis

BMC Musculoskeletal Disorders
Background This study aimed to identify potential biomarkers for the diagnosis and treatment of osteoporosis (OP). Methods Data sets were downloaded from the Gene Expression Omnibus database, and differentially programmed cell death-related genes were ...
Mingliang Li, Xue Wang, Mingbo Guo, Wenlong Zhang, Taotao Li, Jinyang Zheng   +5 more
doaj   +1 more source

Shotgun proteomics of Aspergillus niger microsomes upon D-xylose induction [PDF]

Protein secretion plays an eminent role in cell maintenance and adaptation to the extracellular environment of microorganisms. Although protein secretion is an extremely efficient process in filamentous fungi, the mechanisms underlying protein secretion ...
Ferreira de Oliveira, J.M.P., Graaff, L.H., de, Passel, M.W.J., van, Schaap, P.J.   +3 more
core   +1 more source

VPS35 Gene [PDF]

, 2020
openaire   +1 more source

Generation of two isogenic control iPSC lines (LCSBi001-A-2 and LCSBi001-A-3) from a Parkinson’s disease patient line (LCSBi001-A) carrying the pathogenic VPS35 p.D620N mutation

Stem Cell Research
The pathogenic mutation VPS35 p.D620N has been identified to cause autosomal dominant, late-onset Parkinson’s disease (PD) in multiple individuals and families worldwide.
Ioanna Boumpoureka, Vyron Gorgogietas, Elizabet Petkovski, François Massart, George D. Mellick, Rejko Krüger   +5 more
doaj   +1 more source

Stabilization of the retromer complex: Analysis of novel binding sites of bis-1,3-phenyl guanylhydrazone 2a to the VPS29/VPS35 interface

Computational and Structural Biotechnology Journal
The stabilization of the retromer protein complex can be effective in the treatment of different neurological disorders. Following the identification of bis-1,3-phenyl guanylhydrazone 2a as an effective new compound for the treatment of amyotrophic ...
Elisa Fagnani, Francesco Bonì, Pierfausto Seneci, Davide Gornati, Luca Muzio, Eloise Mastrangelo, Mario Milani   +6 more
doaj   +1 more source

VPS35 wt Allele [PDF]

, 2020
openaire   +1 more source

Novel gene (TMEM230) linked to Parkinson’s disease [PDF]

, 2016

core   +1 more source

VPS35-Retromer: Multifunctional Roles in Various Biological Processes – A Focus on Neurodegenerative Diseases and Cancer

Journal of Inflammation Research
Xiaoyang Fan, Yuqi Xie, Sitong Cao, Li Zhu, Xueting Wang Institute of Special Environmental Medicine, Co-Innovation Center of Neuroregeneration, Nantong University, Nantong, People’s Republic of ChinaCorrespondence: Xueting Wang; Li Zhu, Institute of ...
Fan X, Xie Y, Cao S, Zhu L, Wang X
doaj  

Lysosomal down-regulation of the mu opioid receptor is opposed by the Retromer complex. [PDF]

Sci Adv
Dagunts A, Adoff H, Novy B, Ameur LB, De Maria M, Saunders A, Lobingier BT.   +6 more
europepmc   +1 more source