A hammerhead ribozyme selects mechanically stable conformations for catalysis against viral RNA. [PDF]
Commun BiolLu M +11 more
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CircRNA hsa_circ_0004781 promoted cell proliferation by acting as a sponge for miR-9-5p and miR-338-3p and upregulating KLF5 and ADAM17 expression in pancreatic ductal adenocarcinoma. [PDF]
Cancer Cell IntLee KL +4 more
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A molecular proximity sensor based on an engineered, dual-component guide RNA. [PDF]
ElifeChoi J +4 more
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Minimal twister sister-like self-cleaving ribozymes in the human genome revealed by deep mutational scanning. [PDF]
ElifeZhang Z +5 more
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A mix-and-match reverse genetics system for evaluating genetic determinants of orthobunyavirus neurological disease. [PDF]
PLoS OneMiettinen HM, Abbott MJ, Evans AB.
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Prebiotic chiral transfer from self-aminoacylating ribozymes may favor either handedness. [PDF]
Nat CommunKenchel J +10 more
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Molecular Crowding Facilitates Ribozyme-Catalyzed RNA Assembly. [PDF]
ACS Cent Sci, 2023 DasGupta S, Zhang S, Szostak JW.
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Evaluating Performance of Different RNA Secondary Structure Prediction Programs Using Self-cleaving Ribozymes. [PDF]
Genomics Proteomics BioinformaticsQi F +6 more
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Direct testing of natural twister ribozymes from over a thousand organisms reveals a broad tolerance for structural imperfections. [PDF]
Nucleic Acids ResMcKinley LN +6 more
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Engineering dynamic cell cycle control with synthetic small molecule-responsive RNA devices [PDF]
, 2015 Christina D. Smolke, Kathy Y. Wei
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