Results 91 to 100 of about 470,699 (271)
Vulnerability analysis of three remote voting methods [PDF]
, 2009 This article analyses three methods of remote voting in an uncontrolled environment: postal voting, internet voting and hybrid voting. It breaks down the voting process into different stages and compares their vulnerabilities considering criteria that ...
Enguehard, Chantal, Lehn, Rémi
core +3 more sources
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
ASEAN Social Work JournalAge and Disability Consortium. (2018). Minimum standards for age and disability inclusion in humanitarian action. https://adstandards.org/ Cabauatan, R. J., Mendoza, A. V., & Torres, M. L. (2021). Disaster preparedness and disability inclusion: Gaps in
Kristoper Rex Oraiz, Elmee Joy Oraiz
doaj +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
On Cyber Vulnerabilities Management in Critical Sectors: the Health Sector
Bulletin of "Carol I" National Defense UniversityThe digitalisation of the Romanian health sector has accelerated significantly, especially in the aftermath of the COVID-19 pandemic, but this transition has amplified cybersecurity risks, exposing critical infrastructures and patient data to persistent
Irina-Delia NEMOIANU
doaj +1 more source
A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy
Molecular Oncology, EarlyView.Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti +3 more
wiley +1 more source
JàmbáThe increasing frequency of hazards such as floods, droughts, socio-political unrest, emerging diseases and rising temperatures has affected South Africa.
Davies V. Nkosi +9 more
doaj +1 more source
Evaluating application vulnerability to soft errors in multi-level cache hierarchy [PDF]
, 2011 As the capacity of cache increases dramatically with new processors, soft errors originating in cache has become a major reliability concern for high performance processors.
Carlson, Trevor +3 more
core +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Supply chain resilience and measurement dimensions: The case of halal pharmaceuticals in Malaysia
SHS Web of Conferences, 2018 Resilience is the vital feature of supply chains that confers the ability to withstand the adverse effects of disruptive events. Most of the previous studies have been conceptual, theoretical, normative, or at best qualitative in approach, concentrating ...
Aigbogun Osaro +2 more
doaj +1 more source