Results 51 to 60 of about 452,608 (266)
SSM: Population Health, 2019 Background: Childhood misfortune is associated with late-life depressive symptoms, but it remains an open question whether adult socioeconomic and relational reserves could reduce the association between childhood misfortune and late-life depressive ...
Martina von Arx +10 more
doaj +1 more source
BMC Psychiatry, 2021 Background Undocumented migrants live and work in precarious conditions. Few studies have explored the mental health consequences of such environment.
Julien Fakhoury +5 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Cryptocurrencies: Who is vulnerable and what are the vulnerabilities?
Australian Journal of Social IssuesAbstractAustralians are embracing new forms of digital finance products and services, which includes purchasing cryptocurrencies and non‐fungible tokens (NFTs). There has been an increase in investment scams associated with cryptocurrencies. In this article, we sought to understand from cryptocurrency and NFT investors, who is vulnerable and what ...
Levon Blue, Congcong Xing, Thu Pham
openaire +4 more sources
Current Research in Behavioral SciencesThis study performs a sex-stratified analysis of the prevalence and predictors of suicidal risk behaviors (SRBs) among Paraguayan adolescents, utilizing data from the 2017 Global School-based Student Health Survey (GSHS).
Taufique Ahmed +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
WHAT VULNERABILITY? WHOSE VULNERABILITY? CONFLICT OF UNDERSTANDINGS IN THE DEBATE ON VULNERABILITY
Facta Universitatis, Series: Law and Politics, 2017 In this paper, I intend to explore the apparent difficulty in communication between two understandings of vulnerability: one that claims that vulnerability is a part of conditio humana, a feature closely connected to the facts of (human) embodiment and mortality, and the other which argues for the exclusivity of vulnerability and wishes to limit it to ...
openaire +3 more sources
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source