Results 31 to 40 of about 32,051 (269)
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Trafficked adult men, gendered constructions of vulnerability, and access to protection
, 2021 Trafficking in persons has attracted considerable attention after the adoption of the 2000 Protocol to Prevent, Suppress and Punish Trafficking in Persons, especially Women and Children, and the 2005 Council of Europe Convention on Action against ...
Magugliani, Noemi
core +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Elosztott fenyegetettség felmérés = Distributed Vulnerability Assessment [PDF]
, 2018 Electronic information systems are used in nearly every area of life today. Besides computers smart and IoT devices turn up. However, when IT systems are used online there are cyber-threats too.
Ferenc Leitold +3 more
core +1 more source
Adequacy of Social Services for Persons with Disability of a Second Class City in Negros Occidental
Philippine Social Science Journal, 2020 Persons with Disability (PWDs) comprise one billion or fifteen percent (15%) of the world's total population. Adequacy of social services plays a vital role in realizing the rights and welfare of the PWDs.
Cherry Belle R. Marcella +1 more
doaj +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
A multi-layer framework for the physical protection of military air bases under combined threats
Системи озброєння і військова технікаThis article addresses the problem of improving the physical protection of military air bases under combined threats. The relevance of the study is determined by the growing complexity of the contemporary threat environment, in which military aviation ...
R. Akhundov, E. H. Hashimov
doaj +1 more source
FEBS Letters, EarlyView.Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
An automated context-aware IoT vulnerability assessment rule-set generator
, 2022 While introducing unprecedented applications, Internet of Things (IoT) has simultaneously provoked acute security challenges, in the form of the vulnerabilities.
Hashmat, F +5 more
core +1 more source
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source