Results 71 to 80 of about 2,041,932 (309)

Enhancing Cybersecurity and Privacy Protection for Cloud Computing-Assisted Vehicular Network of Autonomous Electric Vehicles: Applications of Machine Learning

World Electric Vehicle Journal
Due to developments in vehicle engineering and communication technologies, vehicular networks have become an attractive and feasible solution for the future of electric, autonomous, and connected vehicles.
Tiansheng Yang, Ruikai Sun, Rajkumar Singh Rathore, Imran Baig   +3 more
doaj   +1 more source

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

Molecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh, Ji Yun Jang, Yoon Jeon, Gi‐Cheon Kim, Hwanho Lee, Jooyoung Lee, Ju‐Hwa Kim, Hakhyun Kim, Minjee Kim, Ho‐Keun Kwon, Ho Lee, Hyun Seok Kim   +11 more
wiley   +1 more source

Workflow adaptation as an autonomic computing problem [PDF]

, 2007
The performance of long running scientific workflows stands to benefit from adapting to changes in their environment. Autonomic Computing provides methodologies for managing run-time adaptations in managed systems. In this paper, we apply the monitoring,
Fernandes, A.A.A., Kevin Lee, Rizos Sakellariou, Lee, K., Paton, N.W., Sakellariou, R., Norman W. Paton, Alvaro A. A. Fernandes   +7 more
core   +1 more source

CONCEPTUAL FRAMEWORK OF ANALYSIS OF INFORMATION SECURITY MODELS OF CLOUD SYSTEMS OF THE CLASS «INFRASTRUCTURE AS A SERVICE»

Доклады Белорусского государственного университета информатики и радиоэлектроники, 2019
A process based on the role approach for the synthesis of information security models of cloud computing systems based on applied system and threat models is described; the result is a security model, expressed, for example, in recommendations for ...
E. V. Olizarovich, A. I. Brazhuk
doaj   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

Molecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler, Bilal A. Lone, Ecem Unal, A. Rouf Banday   +3 more
wiley   +1 more source

Assessing livelihood vulnerability to sea level rise: a perspective to climate vulnerability and adaptation in the context of the Indian sundarbans delta

Discover Sustainability
The coastal communities of the Indian Sundarbans Delta in West Bengal survive in a socio-ecological system that grapples with existential threats due to Sea Level Rise (SLR).
Anoop Kumar Shukla, Bijoya Ganguli, Nirwan, Sandeep Budde   +3 more
doaj   +1 more source

DETEKSI KONDISI KETAHANAN PANGAN BERAS MENGGUNAKAN PEMODELAN SPASIAL KERENTANAN PANGAN

Journal of Natural Resources and Environmental Management, 2012
In 2005 and 2009, BKP and WFP has provided food security conditions in Indonesia on Food Insecurity Map which were developed using food availability, food accessibility, food absorption and food vulnerability.
Dede Dirgahayu, I Nengah Surati Jaya, Florentina Sri Hardiyanti Purwadhi, Muhammad Ardiansyah, Hermanu Triwidodo   +4 more
doaj   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Measuring the Vulnerability of Subnational Regions [PDF]

A small but growing literature has been concerned about the economic (and environmental) vulnerability on the level of countries. Less attention is paid to the economic vulnerability of different regions within countries. By focusing on the vulnerability
Rossouw, Stephanie, Naude, Wim, McGillivray, Mark   +2 more
core