Results 61 to 70 of about 372,889 (280)

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

An Iterative and Toolchain-Based Approach to Automate Scanning and Mapping Computer Networks

, 2017
As today's organizational computer networks are ever evolving and becoming more and more complex, finding potential vulnerabilities and conducting security audits has become a crucial element in securing these networks.
Bray B., Chatzimisios P., Cheng F., Convery S., Fuller V., Koc A., Lyon G., Membrey P., Orebaugh A., Shelly D. A., Ward M.   +10 more
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Vulnerabilities Detection by Matching with known Vulnerabilities

INTERANTIONAL JOURNAL OF SCIENTIFIC RESEARCH IN ENGINEERING AND MANAGEMENT
Vulnerability Matcher is a tool designed to identify and prioritize security vulnerabilities in software systems. This intelligent system leverages advanced machine learning algorithms to analyze and match identified vulnerabilities with known security threats and exploits.
Precious Jeo John, Sumit Surendran
openaire   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

IoT Firmware Emulation and Its Security Application in Fuzzing: A Critical Revisit

Future Internet
As IoT devices with microcontroller (MCU)-based firmware become more common in our lives, memory corruption vulnerabilities in their firmware are increasingly targeted by adversaries.
Wei Zhou, Shandian Shen, Peng Liu
doaj   +1 more source

AndroShield: Automated Android Applications Vulnerability Detection, a Hybrid Static and Dynamic Analysis Approach

Information, 2019
The security of mobile applications has become a major research field which is associated with a lot of challenges. The high rate of developing mobile applications has resulted in less secure applications. This is due to what is called the “rush to
Amr Amin, Amgad Eldessouki, Menna Tullah Magdy, Nouran Abdeen, Hanan Hindy, Islam Hegazy   +5 more
doaj   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

A Coverage-Guided Fuzzing Method for Automatic Software Vulnerability Detection Using Reinforcement Learning-Enabled Multi-Level Input Mutation

IEEE Access
Fuzzing is a popular and effective software testing technique that automatically generates or modifies inputs to test the stability and vulnerabilities of a software system, which has been widely applied and improved by security researchers and experts ...
Van-Hau Pham, Do Thi Thu Hien, Nguyen Phuc Chuong, Pham Thanh Thai, Phan The Duy   +4 more
doaj   +1 more source