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From Vulnerable Plaque to Vulnerable Patient: The Search for Biomarkers of Plaque Destabilization
Trends in Cardiovascular Medicine, 2007There is a strong need for biomarkers to identify patients at risk for future cardiovascular events related with progressive atherosclerotic disease. Ideally, increasing knowledge of the mechanisms of atherosclerotic plaque destabilization should be translated in clinical practice. Currently, the following commonly followed strategies can be identified
Willem E, Hellings +3 more
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Thermal detection of vulnerable plaque
The American Journal of Cardiology, 2002In 1996, we showed that inflamed atherosclerotic plaques give off more heat and that vulnerable plaques may be detected by measuring their temperature. Plaque temperature is correlated directly with inflammatory cell density and inversely with the distance of the cell clusters from the luminal surface.
Mohammad, Madjid +5 more
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Molecular Imaging of Vulnerable Plaque
Seminars in Nuclear Medicine, 2018Molecular imaging provides multiple imaging techniques to identify characteristics of vulnerable plaque including I) Inflammatory cells (the presence and metabolic activity of macrophages), II) synthesis of lipid and fatty acid in the plaque, III) the presence of hypoxia in severely inflamed lesions, IV) expression of factors stimulating angiogenesis ...
Takehiro, Nakahara +2 more
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A Non‐Invasive Nanoprobe for In Vivo Photoacoustic Imaging of Vulnerable Atherosclerotic Plaque
Advanced Materials, 2020Jian Kong, Shi-Yu Lu, Shuang-Yan Lin
exaly
Vulnerable Atherosclerotic Plaque: Is There a Molecular Signature?
International Journal of Molecular Sciences, 2022Roxana Mihaela Chiorescu +2 more
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