Results 231 to 240 of about 2,628,839 (264)

Early Retinal UCHL1 Dysregulation Coupled With Synaptic Loss Reflects Alzheimer's Disease Severity

Advanced Science, EarlyView.
This study identifies synapse‐enriched deubiquitinase UCHL1 as an early Aβ‐responsive regulator of retinal synaptopathy in Alzheimer's disease. Retinal UCHL1 loss accompanies excitatory synapse degeneration, p75NTR activation, and neuroinflammation, and predicts Braak stage and cognitive decline. Aβ42 fibrils trigger synaptic and UCHL1 depletion before
Altan Rentsendorj, Jean‐Philippe Vit, Alexandre Hutton, Yosef Koronyo, Saba Shahin, Edward Robinson, Ernesto Barron, Anthony Rodriguez, Ousman Jallow, Julia Sheyn, Bhakta Prasad Gaire, Lalita Subedi, Miyah R. Davis, Barathan Gnanabharathi, Alexander V. Ljubimov, Stuart L. Graham, Vivek K. Gupta, Mehdi Mirzaei, Debra Hawes, Katlin Silm, Keith L. Black, Lon S. Schneider, Alfredo A. Sadun, Jesse G. Meyer, Dieu‐Trang Fuchs, Maya Koronyo‐Hamaoui   +25 more
wiley   +1 more source

Determinants Shaping Healthcare Experiences Among Vulnerable Populations in Hong Kong: A Qualitative Descriptive Study. [PDF]

J Prim Care Community Health
Lam MCY, Wong KOK, Lim YC, Maryam AM, Chong WYJ, Khong ML, Luk PLP.   +6 more
europepmc   +1 more source

Multidimensional and Multifunctional Laser‐Induced Graphene (LIG) for Point‐of‐Care and Wearable Biosensing, Theranostics, and Bioactive Interfaces Toward Personalized Healthcare and Regenerative Medicine

Advanced Science, EarlyView.
Multidimensional laser‐induced graphene (LIG) spanning from 0D to 3D architectures is comprehensively reviewed for multifunctional biomedical platforms, including biosensing, theranostics, and bioactive interface applications, which highlights its potentials for point‐of‐care diagnostics, wearable health monitoring, smart drug delivery, and tissue ...
Li Zhang, Yurou Yuan, Xiaohong Ding, Wing Cheung Mak   +3 more
wiley   +1 more source

The impact of extreme weather events on the mental health of vulnerable populations in Africa (The WEMA project): a study protocol

Mthiyane N, Ndlovu S, Kiragga A, Tanser F, Bunker A, Cumbe V, Ramiro I, Muanido A, Odero H, Omondi E, Liyanage P, Lindner E, Traoré N, Sié A, Barnighausen T, Otieno F, Wambua GN, Akinyi LJ, Khagayi S, Mulopo C, Wekesah FM, Treffry-Goatley A, Black GF, Iwuji C.   +23 more
europepmc   +1 more source

The development and use of chatbots in enhancing health care access for underserved and vulnerable populations: a scoping review. [PDF]

BMC Public Health
Hazhir S, Langarizadeh M, Bahariniya S, Valizadeh Laktarashi H, Hami A, Fatemi Aghda SA.   +5 more
europepmc   +1 more source

Microalgae Hybrid Biosystem for Enhanced Oral Delivery of Rifaximin in Hepatic Encephalopathy Treatment

Advanced Science, EarlyView.
The microalgae‐nanoparticle hybrid system with antibacterial activity can improve the oral delivery and therapeutic efficiency for hepatic encephalopathy treatment. Oral administration of the system can reduced systemic ammonia levels, enhanced intestinal barrier function, attenuated systemic and neuroinflammation, ameliorated cognitive impairments ...
Kaiyue Wang, Xueting Huang, Lingxiao Yang, Jin Liu, Lei Lei, Shaomin Zou, Kai Wang, Min Zhou, Zhe Tang   +8 more
wiley   +1 more source

Corrigendum to “Tobacco use behaviors and views on engaging in clinical trials for tobacco cessation among individuals who experience homelessness” [Contemporary Clinic. Trials Commun. 32 (2023) 101094]

Contemporary Clinical Trials Communications
Joshua Miller, Jordan Cuby, Sharon M. Hall, Maxine Stitzer, Margot Kushel, Donna Appiah, Maya Vijayaraghavan   +6 more
doaj   +1 more source

Editorial: Exploring mental health in vulnerable populations in developing countries. [PDF]

Front Public Health
Sarfo JO.
europepmc   +1 more source

COMBINA: The EAAD four-level approach for depression and suicide prevention and wellbeing promotion in the community and vulnerable populations. A cross-country study protocol from the MENTBEST project. [PDF]

PLoS One
Hogg B, Coppens E, Gatto DL, de Córdoba-Gil C, Ayuso Mateos JL, Bakiu K, Callanan A, Pashoja AC, Conceição V, Dandi E, Faurholt-Jepsen M, Katsoridou C, Khan A, Luyten J, McGreevy KR, Mere R, O'Shea D, Papaioannou G, Qirjako G, Reich H, Värnik P, Värnik A, Vivas AB, Arensman E, Van Audenhove C, Gusmão R, Amann BL, Schnitzspahn K, Hegerl U.   +28 more
europepmc   +1 more source

Cost-effectiveness analysis of hepatitis E screening and vaccination: targeting vulnerable populations in outbreak and sporadic settings in China. [PDF]

Emerg Microbes Infect
Liu H, Chen G, Jie Y, Jiang Y, Huang Y, Wang X, Hao C, Gu J, Zhang L, Li J.   +9 more
europepmc   +1 more source