Results 241 to 250 of about 8,761,625 (347)

Comprehensive Management of Multisite Myiasis in a Critically Ill Patient: A Case Report Highlighting Challenges in Vulnerable Populations. [PDF]

Case Rep Infect Dis
Shiari A, Muhanad M, Zurob A.
europepmc   +1 more source

DMAP1 Deficiency Suppresses Lung Cancer Progression by Destabilizing Replication Fork and Activating IFN Signaling‐Mediated Anti‐tumor Immunity

Advanced Science, EarlyView.
Lung cancer remains the leading cause of cancer‐related death. We investigated the role of the epigenetic regulator DMAP1 in NSCLC and found that its loss induces replication stress and DNA damage. This in turn activates type I IFN signaling via the cGAS–STING pathway and transcriptional ISG de‐repression, enhancing anti‐tumor immune responses ...
Kan Huang, Xi Dai, Shuaihu Li, Yingxue Chen, Yaxin Yu, Lin Wang, Kun Liu, Shuhan Lyu, Chongyang Li, Yihua Sun, Fei Li   +10 more
wiley   +1 more source

Using a Transdisciplinary Approach in Learning Communities for Designing Wearable Stress Management for Vulnerable Populations: Development and Usability Study. [PDF]

JMIR Form Res
Peeters MWH, Mannheim I, van Westrienen PE, van Dijk L, Elia A, Valterova K, van de Garde-Perik E, Heck P, Lavrijssen N, Schouten G, Wouters EJM.   +10 more
europepmc   +1 more source

Financial incentives and vulnerable populations — will alternative payment models help or hurt? [PDF]

, 2018
Joynt Maddox, Karen E.
core   +2 more sources

SKOOTS: Skeleton‐Oriented Object Segmentation for Mitochondria in High‐Resolution Cochlear EM Datasets

Advanced Science, EarlyView.
Skeleton‐oriented object segmentation (SKOOTS) introduces a new strategy for 3D mitochondrial instance segmentation by predicting explicit skeletons rather than relying on boundary cues. This approach enables robust analysis of densely packed organelles in large FIB‐SEM datasets.
Christopher J. Buswinka, Richard T. Osgood, Hidetomi Nitta, Artur A. Indzhykulian   +3 more
wiley   +1 more source

Editorial: Oral health and quality of life in vulnerable populations. [PDF]

Front Oral Health
Mehta V, Karobari MI, Fiorillo L.
europepmc   +1 more source

Regulating Research with Vulnerable Populations: Litigation Gone Awry [PDF]

, 1998
Delano, Susan J., Haimowitz, Stephan, Oldham, John M.   +2 more
core  

Localized NF‐κB Inhibition Reduces Lipid Nanoparticle‐Associated Inflammation

Advanced Science, EarlyView.
Lipid nanoparticles (LNPs) activate NF‐κB and provoke inflammation that limits therapeutic delivery. By encapsulating selective NF‐κB inhibitors within LNPs, localized suppression of inflammatory signaling is achieved without compromising mRNA expression.
Carolann L. Espy, Jichuan Wu, Serena Omo‐Lamai, Liuqian Wang, Fengyi Dong, Aleksa Milosavljevic, Sarah O'Neill, Taylor Brysgel, Yufei Wang, Michael Zaleski, Emily Wolfe, Rhea Maheshwari, Manthan Patel, Dirk Trauner, Jia Nong, Zhicheng Wang, Jacob S. Brenner   +16 more
wiley   +1 more source

Video recording as a data collection method in vulnerable populations - methodological and ethical considerations. [PDF]

PEC Innov
Karlsen MW, Sørensen K, Hofset Larsen B, Heyn LG, Gerwing J.   +4 more
europepmc   +1 more source

Decoding IGLL5 Mutation‐Mediated BCR Signaling: A Novel Mechanism of CD8+ T Cell Exhaustion and Ocular MALT Lymphoma Progression

Advanced Science, EarlyView.
OAML harbors recurrent IGLL5 mutations that reinforce CD79A/CD79B‐associated BCR signaling. Mechanistic analysis of the S47G and A54G variants reveals induction of CXCL10/CXCL11, enhanced CD8+ T‐cell recruitment, and exhaustion‐associated dysfunction, supporting an immune‐tolerant niche.
Andi Zhao, Haoyu Wei, Chenyu Zhou, Xinping Sun, Shuyan Da, Haiyu Liu, Zijin Wang, Hui Zhu, Shiya Shen, Qing Shao, Qi Gong, Hu Liu, Xuejuan Chen   +12 more
wiley   +1 more source