Results 41 to 50 of about 186,991 (298)

Towards Improved Protection of Vulnerable Road Users [PDF]

open access: yesTransactions on Transport Sciences, 2011
The paper aims at reducing injury risk and an overall increase in pedestrian passive safety by proposing pedestrian friendly vehicle design. Statistical data are used to identify the most vulnerable population group also regarding the economic losses caused by deaths or medical treatment. An age dependent anthropometric approach enables the development
L. Hynčík   +3 more
openaire   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Evaluating the effect of drunk driving on fatal injuries among vulnerable road users in Taiwan: a population-based study

open access: yesBMC Public Health, 2022
Background Most studies have focused on injuries sustained by intoxicated drivers themselves, but few have examined the effect of drunk driving on injury outcomes among VRUs (vulnerable road users) in developing countries. This study aims to evaluate the
Hui-An Lin   +8 more
doaj   +1 more source

A Sensing, Communication and Computing Approach for Vulnerable Road Users Safety

open access: yesIEEE Access, 2023
Most fatal road accidents in urban areas involve vulnerable road users. New solutions for fighting against these accidents can be considered by leveraging connected, intelligent vehicles and smart cities connecting all parts of an urban environment. This
Pedro Teixeira   +4 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

open access: yesMolecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken   +3 more
wiley   +1 more source

What factors impact pedestrian and cyclist fatalities? A state level analysis

open access: yesInjury Epidemiology, 2021
Background Pedestrian and bicyclist injuries and fatalities have increased since 2010 after a long downward trend. Trucks and SUVs, collectively called light trucks, have also increased in sales and size, which may affect pedestrians and bicyclists ...
Zoabe Hafeez, Malvi Mehta
doaj   +1 more source

Problems for Vulnerable Road Users in Great Britain, The Netherlands and Sweden [PDF]

open access: yes, 1989
INTRODUCTION In many countries in Europe pedal cycle and pedestrian travel are important transport modes for the population. However, given the vulnerable nature of these modes of transport, the number of accidents involving pedestrians and cyclists ...
Carsten, O.M.J.   +2 more
core  

People tracking by cooperative fusion of RADAR and camera sensors [PDF]

open access: yes, 2019
Accurate 3D tracking of objects from monocular camera poses challenges due to the loss of depth during projection. Although ranging by RADAR has proven effective in highway environments, people tracking remains beyond the capability of single sensor ...
Dimitrievski, Martin   +3 more
core   +2 more sources

Anticancer sensitivities and biological characteristics of HCT116 cells resistant to the selective poly(ADP‐ribose) glycohydrolase inhibitor

open access: yesFEBS Open Bio, EarlyView.
We analyzed alterations of PAR metabolism‐related proteins in PARG inhibitor‐resistant HCT116RPDD cells. Although PARG levels remained unchanged, HCT116RPDD cells exhibited reduced PARP1 and ARH3 expression and elevated PAR levels. Interestingly, HCT116RPDD cells exhibited slightly elevated intracellular NAD+/NADH and ATP levels. Our findings suggest a
Kaede Tsuda, Yoko Ogino, Akira Sato
wiley   +1 more source

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