Results 101 to 110 of about 29,769 (281)

Th17 cells favor migration and invasiveness of cervical cancer cells under hypoxia in an IGF2BP2‐dependent manner

International Journal of Cancer, Volume 158, Issue 11, Page 3021-3037, 1 June 2026.
What's new? Hypoxic regions and inflammatory Th17 cells in the tumor environment are both associated with poor prognosis in cervical cancer. However, synergistic mechanisms between hypoxia and Th17 cells remain elusive. This study demonstrated Th17–hypoxia‐driven mechanisms underlying cervical cancer progression.
Selina Gies, Maike Pohlers, Tanja Tänzer, Emmanuel Ampofo, Matthias W. Laschke, Moritz Schäfer, Yoo‐Jin Kim, Rainer Maria Bohle, Erich‐Franz Solomayer, Konrad Wagner, Martin Empting, Alexandra K. Kiemer, Barbara Walch‐Rückheim   +12 more
wiley   +1 more source

The impact of surgery for vulval cancer upon health-related quality of life and pelvic floor outcomes during the first year of treatment: A longitudinal, mixed methods study [PDF]

, 2015
© 2015 The Authors.Objective: To measure the long-term impact of surgical treatment for vulval cancer upon health-related quality of life and pelvic floor outcomes during the first year of therapy. Methods: Prospective, longitudinal, mixed-methods study.
Alazzam, M, Hughes, J, Jacques, RM, Jones, GL, Ledger, W, Radley, SC, Thompson, J, Tidy, JA, Wood, HJ   +8 more
core   +1 more source

Management of vulvar cancers

European Journal of Surgical Oncology (EJSO), 2006
The radical surgical approach in the treatment of vulvar cancer patients has led to a favorable prognosis for the majority of the patients with early stage squamous cell cancer. However, the morbidity is impressive, leading to more individualized treatment.
Hullu, J.A. de, Avoort, I.A.M. van der, Oonk, M.H., Zee, A.G. van der   +3 more
openaire   +3 more sources

Nonavalent HPV vaccine to prevent recurrent anal or vulvar high‐grade squamous intraepithelial lesions (VIVA trial): A randomized, double‐blind, placebo‐controlled trial

International Journal of Cancer, Volume 158, Issue 11, Page 2983-2994, 1 June 2026.
What's new? Anal and vulvar high‐grade squamous intraepithelial lesions (HSILs) frequently recur following treatment. Additional genital and anal procedures, however, can be distressing for patients and are potentially disfiguring. This trial assessed whether the 9‐valent human papillomavirus (9vHPV) vaccine reduces HSIL recurrence risk or HPV ...
Helen C. Stankiewicz Karita, Amalia S. Magaret, David R. Doody, Jeffrey T. Schouten, Constance Mao, Warner K. Huh, Verena S. Grieco, Matthew A. Seymour, Dana Varon, Kelly H. Shrader, Long Fu Xi, Denise A. Galloway, Anna Wald, Margaret M. Madeleine   +13 more
wiley   +1 more source

Cost-effectiveness of sentinel lymph node biopsy vs inguinofemoral lymphadenectomy in women with vulval cancer [PDF]

, 2013
background: This study examines the cost-effectiveness of sentinel lymph node biopsy, a potentially less morbid procedure, compared with inguinofemoral lymphadenectomy (IFL) among women with stage I and stage II vulval squamous cell carcinoma. methods: A
A Brennan, A J Sutton, A N Rosenthal, AG van der Zee, AM Gray, C Meads, EJ Crosbie, JA de Hullu, JA de Hullu, JA Fonseca-Moutinho, JC Macnab, K Khan, L Elit, M Hampl, MH Oonk, MH Oonk, MH Oonk, N Devlin, P Baldwin, P Barton, P Barton, RG Moore, S Sundar, T E Roberts, TJ Selman, TJ Selman   +25 more
core   +2 more sources

Changes in the 6th edition of the World Health Organization classification of tumours of the digestive system

Histopathology, Volume 88, Issue 7, Page 1295-1314, June 2026.
Changes and new entities in the 6th edition WCT of the digestive system, including structural, molecular, and diagnostic updates to standardize terminology and improve clinical relevance. Epithelial tumours are organized by site; neuroendocrine, mesenchymal and haematolymphoid tumours have dedicated chapters, with refined grading, redefined ...
Mark J Arends, Irene Esposito, Anthony J Gill, Ralph H Hruban, Joseph D Khoury, Motohiro Kojima, Elizabeth A Montgomery, Fatimah Abdulkareem, Fátima Carneiro, Guido Costamagna, Gregory Lauwers, Alexandros D Polydorides, Guido Rindi, Massimo Rugge, Peter Schirmacher, Amitabh Srivastava, James Yao, Jennelle C Hodge, James G Kench, Bharat Rekhi, Miguel Reyes‐Múgica, Antonia R Sepulveda, Chanjuan Shi, Pavitratha Puspanathan, Harshima Wijesinghe, Christine Giesen, Blanca Iciar Indave Ruiz, Dilani Lokuhetty, WCT standing editorial board, Iris D Nagtegaal, Wendy Cooper, Michael Eden, Andrew Field, Vicky Goh, Jennelle Hodge, James Kench, Joseph Khoury, Katia Leite, Zhiyong Liang, Daichi Maeda, George Netto, Bharat Rekhi, Miguel Reyes Múgica, Brian Rous, Ales Ryska, Shahin Sayed, Antonia R Sepulveda, Chanjuan Shi, Gary Tse   +48 more
wiley   +1 more source

The tell-tale heart: A case of recurrent vulvar carcinoma with cardiac metastasis and review of literature

Gynecologic Oncology Reports, 2017
A 50-year-old female was diagnosed with vulvar cancer treated with left partial vulvectomy and bilateral lymphadenectomy. Ten months after her surgery, she presented with increased labial swelling, pain and discharge.
Syed Imran Mustafa Jafri, Naveed Ali, Salman Farhat, Faizan Malik, Mark Shahin   +4 more
doaj   +1 more source

Vulvar cancer in pregnancy

Journal of Obstetrics and Gynaecology, 1998
these conditions. The disease occurs most commonly during the sixth decade of life although 15% of vulvar cancers develop in women less than 40 years of age (Henson and Tarone, 1977). We believe this case report presents the youngest patient (18 years old) with vulvar cancer in pregnancy ever reported.
F, Alexander-Sefre, M, Morcos, W, Mohamid, A J, Minchin   +3 more
openaire   +2 more sources

Nonmass‐Forming Type Anocanal Cancer With Pagetoid Spread With a Challenging Differential Diagnosis: A Case Report

Clinical Case Reports, Volume 14, Issue 5, May 2026.
ABSTRACT Pagetoid spread (PS) of anorectal cancer is relatively rare and is associated with poor prognosis compared with Extramammary Paget disease. It is therefore essential to accurately differentiate between the two entities. In PS cases, the primary tumor lesion is usually obvious; however, this is not the case in nonmass‐forming type anorectal ...
Mizunori Yaegashi, Ryo Sugimoto, Hiroaki Shimada, Akira Sasaki   +3 more
wiley   +1 more source

#626 The use of plasmajet® in the treatment of vulvar intraepithelial neoplasia: results from 48 patients in a UK gynaecological cancer centre [PDF]

, 2023
Natasha Rinne, Shriya Varghese, Stacey Bryan, Benjamin P. Jones, Sadaf Ghaem‐Maghami, Srdjan Saso, James R. Smith   +6 more
openalex   +1 more source