Results 51 to 60 of about 26,766 (270)

Atrophic vulvar lichen sclerosus evolving to an epidermoid carcinoma: about an uncommon case

PAMJ Clinical Medicine, 2019
Malignant tumors of the vulva are usually budding, ulcerated, or infiltrating. The fear of cancer must always be in mind, in front of any vulvar lesion.
Abderrahim Siati, Aziz Slaoui, Sarah Talib, Abdelaziz Baidada, Aicha Kharbach   +4 more
doaj   +1 more source

Gracilis myocutaneous flap for perineal defect reconstruction after left hemivulvectomy for locally invasive vulvar cancer – A case report and a literature review [PDF]

, 2019
Performing radical surgery for locally advanced vulvar cancer is usually associated with the occurrence of large perineal defects. In order to provide a better healing process of the perineal wound, different reconstructive techniques have been proposed.
Bacalbasa, Nicolae, Balescu, Irina, Brezean, Iulian, Ghelmene, Adriana, Mereuta, Andreea, Tanase, Alina, Vilcu, Mihaela   +6 more
core   +1 more source

Phosphatidylinositol 3-kinase pathway genomic alterations in 60,991 diverse solid tumors informs targeted therapy opportunities. [PDF]

, 2019
BackgroundThe phosphatidylinositol 3-kinase (PI3K) pathway is frequently altered in cancer. This report describes the landscape of PI3K alterations in solid tumors as well as co-alterations serving as potential resistance/attenuation mechanisms ...
Albacker, Lee, Ali, Siraj M, Jardim, Denis L, Kurzrock, Razelle, Miller, Vincent A, Millis, Sherri Z, Ross, Jeffrey S   +6 more
core   +1 more source

Randomised trial on treatment of vaginal high‐grade squamous intraepithelial lesion: Self‐administered vaginal imiquimod and laser vaporisation

International Journal of Cancer, EarlyView.
What's New? Vaginal high‐grade squamous intraepithelial lesions (HSILs), precursors of vaginal cancer that are related to human papillomavirus (HPV) infection, often are treated with laser vaporization. HSIL treated in this way, however, tends to recur.
Mari Kiviharju, Annika Riska, Ilkka Kalliala, Maija Jakobsson, Annu Heinonen, Joakim Dillner, Pekka Nieminen, Karoliina Aro   +7 more
wiley   +1 more source

Vulvar cancer in Iran: Retrospective study over 20 years (1998-2018)

Journal of Family Medicine and Primary Care, 2019
Background: We did not have any data about vulvar cancer — as a fourth cause of gynecological cancer in the worldwide — in our country. Study Design: Our study is designed to evaluate the frequency, stage and outcome of patients with vulvar cancer ...
Azamosadat Mousavi, Azadeh Yousefnezhad, Mitra Modarres-Gilani, Setareh Akhavan, Shahrzad Sheikh-Hasani   +4 more
doaj   +1 more source

Innovative approaches to the treatment of local recurrent vulvar cancer in patients with lichen sclerosus

Опухоли женской репродуктивной системы, 2023
Background. In recent years, there has been an increase in the incidence of vulvar precancer (lichen sclerosus), as well as vulvar cancer. Since this disorder is rare, treatment planning and therapy itself are often suboptimal, which results in a high ...
A. V. Zharov, E. G. Novikova, A. G. Rerberg, E. V. Kolesnikova   +3 more
doaj   +1 more source

Surgical Management of Vulvar Cancer [PDF]

Journal of the National Comprehensive Cancer Network, 2016
Vulvar cancer is a rare malignancy with high curability in early-stage disease, yet poor outcomes for advanced-stage and recurrent disease. Surgical management is at the cornerstone of treatment for most vulvar cancers, and includes conservative and radical resection of the primary vulvar tumor and excision of local lymph nodes, which are major ...
Ernest S. Han, Mark T. Wakabayashi, Amy Hakim, Thanh H. Dellinger, Stephen J. Lee, Robert J. Morgan   +5 more
openaire   +3 more sources

Prognostic impact of p16 and high‐risk HPV DNA in ~1300 patients with vulvar cancer

International Journal of Cancer, EarlyView.
What's New? Vulvar cancer (VSCC) is rare, and little is known about early prognostic factors that could contribute to an individualized treatment plan. About 30%–40% of VSCCs are associated with human papillomavirus (HPV). Here, the authors investigated the prognostic influence of p16 status in VSCC in a large cohort of 1300 patients.
Susanne K. Kjær, Kirsten Frederiksen, Christina L. Rasmussen, Louise T. Thomsen, Else M. Madsen, Maria B. Franzmann, Alexander K. Kjær, Lise G. Larsen, Nadia V. Salinas, Doris Schledermann, Birgitte H. Winberg, Pernille T. Jensen, Dorthe Ørnskov, Marianne Waldstrøm, Louise Baandrup   +14 more
wiley   +1 more source

CACA guidelines for vulvar malignancies

Holistic Integrative Oncology
Objective The purpose of this study is to provide reference and guidance for the clinical diagnosis and treatment of vulvar malignancies. Method This article sorts out and integrates the contents of vulvar malignancies in the field of traditional Chinese
Zhongqiu Lin, Huaiwu Lu, Jing Wang, Xiaofei Tian, Tao Zhu, Bin Li, Kaijiang Liu, Danbo Wang, Yuhao Zhang, Lingling Xie   +9 more
doaj   +1 more source

Indocyanine green utility in sentinel node detection for cervical cancer patients [PDF]

, 2019
With wide implementation of screening tests for the Human Papilloma Virus, the number of diagnosed cases of premalignant or early stages of cervical cancer has increased considerably.
Bacalbașa, Nicolae, Balalau, Cristian, Balescu, Irina, Brezean, Iulian, Vilcu, Mihaela   +4 more
core   +2 more sources