Results 61 to 70 of about 4,977,677 (230)

Vulvar Cancer, Version 3.2024, NCCN Clinical Practice Guidelines in Oncology.

The Journal of the National Comprehensive Cancer Network
Vulvar cancer is annually diagnosed in an estimated 6,470 individuals and the vast majority are histologically squamous cell carcinomas. Vulvar cancer accounts for 5% to 8% of gynecologic malignancies.
N. Abu-Rustum, C. Yashar, Rebecca Arend, Emma Barber, Kristin Bradley, Rebecca Brooks, Susan M. Campos, Junzo Chino, H. Chon, M. Crispens, Shari Damast, Christine M. Fisher, Peter Frederick, David K. Gaffney, Stephanie Gaillard, Robert Giuntoli, Scott Glaser, Jordan Holmes, Brooke E Howitt, Kari Kendra, Jayanthi Lea, Nita Lee, G. Mantia-Smaldone, Andrea Mariani, David Mutch, Christa Nagel, Larissa Nekhlyudov, Mirna B. Podoll, Kerry J Rodabaugh, Ritu Salani, John Schorge, Jean Siedel, Rachel Sisodia, P. Soliman, Stefanie Ueda, Renata Urban, S. Wethington, E. Wyse, K. Zanotti, Nicole R Mcmillian, Sara Espinosa   +40 more
semanticscholar   +1 more source

Incidence patterns and temporal trends of invasive nonmelanotic vulvar tumors in Germany 1999-2011. A population-based cancer registry analysis. [PDF]

PLoS ONE, 2015
Time trends on the incidence and characteristics of invasive vulvar cancer in Germany have so far been studied in few local population- and hospital based tumor registries.
Nina Buttmann-Schweiger, Stefanie J Klug, Alexander Luyten, Bernd Holleczek, Florian Heitz, Andreas du Bois, Klaus Kraywinkel   +6 more
doaj   +1 more source

High-risk human papillomavirus-associated vulvar neoplasia among women living with human immunodeficiency virus in Zambia

African Journal of Laboratory Medicine, 2022
Background: Globally, women living with HIV have a higher risk of vulvar neoplasia than HIV-negative women. Vulvar neoplasia among women living with HIV has not previously been characterised in Zambia.
Fred Maate, Peter Julius, Stepfanie Siyumbwa, Leeya Pinder, Trevor Kaile, Mulindi Mwanahamuntu, Groesbeck Parham   +6 more
doaj   +1 more source

Vulvar melanoma: relevant aspects in therapeutic management [PDF]

Anais Brasileiros de Dermatologia, 2017
Cancer of the vulva accounts for at least 1% of malignant neoplasms among women. Although rare, vulvar melanoma is the second most common histological type of vulvar cancer, representing 7-10% of all malignant vulvar neoplasms.
Adriana Bittencourt Campaner, Gustavo Leme Fernandes, Fernanda de Araujo Cardoso, John Verrinder Veasey   +3 more
doaj   +1 more source

Stromal Regulation of Tumor Perineural Invasion: A Multicellular and Neuro‐Ecological Perspective

Advanced Science, EarlyView.
This review reframes perineural invasion (PNI) as a dynamic, multicellular process within the tumor–nerve–stromal ecosystem. The authors delineate how cancer‐associated fibroblasts, Schwann cells, and immune cells remodel the neural niche to facilitate tumor spread.
Xiaoyang Lin, Yingqiao Liu, Haitao Lin, Kang Feng, Xiqiang Liu   +4 more
wiley   +1 more source

Extended High‐Risk HPV Genotyping With BD Onclarity Enhances Anal Cancer Screening Among High‐Risk Populations: A Cross‐Sectional Study

Diagnostic Cytopathology, EarlyView.
ABSTRACT Background Anal cancer rates are rising among women, immunocompromised individuals, and Men who have sex with Men (MSM), independent of HIV status. While high‐resolution anoscopy remains the diagnostic standard, limited access has increased interest in alternative screening.
Daisy Maharjan, Joshua Waters, Melissa Randolph, Benjamin Shuler, Julie Borum, Sheila Segura   +5 more
wiley   +1 more source

Therapeutic Approaches to Vulvar Cancer: A Review of Literature

Clinical and Experimental Obstetrics & Gynecology, 2023
Objective: Vulvar cancer is a rare gynecological cancer that mainly affects postmenopausal women. The aim of this review is to analyze the most recent data available in the literature on the clinical and therapeutic approach to vulvar carcinoma ...
Tullio Golia D'Augè, Ilaria Firulli, Giorgia Di Bartolomeo, Ilaria Cuccu, Camilla Turetta, Angelo Trezza, Giorgio Bogani, Innocenza Palaia, Giorgia Perniola, Federica Tomao, Ludovico Muzii, Violante Di Donato, Ottavia D'Oria, Andrea Giannini   +13 more
doaj   +1 more source

Vulvar cancer subclassification by HPV and p53 status results in three clinically distinct subtypes.

Gynecologic Oncology, 2020
OBJECTIVE There is great need for better risk stratification in vulvar squamous cell carcinoma (VSCC). Our aim was to define the prognostic significance of stratifying VSCC based on p16 and p53 immunohistochemistry (IHC) as surrogate markers for HPV and ...
K. Kortekaas, E. Bastiaannet, Helena C. van Doorn, Peggy J. de Vos van Steenwijk, P. Ewing-Graham, C. Creutzberg, K. Akdeniz, L. Nooij, S. H. van der Burg, T. Bosse, M. van Poelgeest   +10 more
semanticscholar   +1 more source

The role of Rho GTPases in facial morphogenesis

Developmental Dynamics, EarlyView.
The role of small GTPases, RHOA, RAC1, and CDC42 and pathway mediators is reviewed in the context of embryonic facial development. Lip fusion requires cytoskeletal remodeling during morphogenesis of the facial processes and during lip fusion. Fnm, frontonasal mass; lnp, lateral nasal process; mnp, medial nasal process; mxp, maxillary process; np, nasal
Isra Ibrahim, Joy M. Richman
wiley   +1 more source

Vulvar cancer in Iran: Retrospective study over 20 years (1998-2018)

Journal of Family Medicine and Primary Care, 2019
Background: We did not have any data about vulvar cancer — as a fourth cause of gynecological cancer in the worldwide — in our country. Study Design: Our study is designed to evaluate the frequency, stage and outcome of patients with vulvar cancer ...
Azamosadat Mousavi, Azadeh Yousefnezhad, Mitra Modarres-Gilani, Setareh Akhavan, Shahrzad Sheikh-Hasani   +4 more
doaj   +1 more source