Evaluation of the burden of HPV-related hospitalizations as a useful tool to increase awareness: 2007–2017 data from the sicilian hospital discharge records [PDF]
In light of the implementation of human papillomavirus (HPV) prevention strategies, epidemiological studies in different geographical areas are required in order to assess the impact of HPV-related diseases.
Amato L.+10 more
core +1 more source
Vulvar cancer in Tunisia: Epidemiological and clinicopathological features multicentric study
Objective: To describe for the first time the epidemiologic and clinico-pathologic characteristics of vulvar cancer in Tunisia. Design: Two parts are distinguished in this study: Part1: Multicentric retrospective study about the characteristics of all ...
Mehdi Kehila, MD+12 more
doaj +1 more source
Role of human papillomavirus infection in the etiology of vulvar cancer in Italian women
Vulvar squamous cell carcinoma (VSCC) is a rare malignancy of the female genital tract. We aimed to determine the mucosal high-risk human papillomavirus (HPV)-attributable fraction of VSCCs from Italian women using multiple markers of viral infections ...
M. Preti+13 more
semanticscholar +1 more source
Gracilis myocutaneous flap for perineal defect reconstruction after left hemivulvectomy for locally invasive vulvar cancer – A case report and a literature review [PDF]
Performing radical surgery for locally advanced vulvar cancer is usually associated with the occurrence of large perineal defects. In order to provide a better healing process of the perineal wound, different reconstructive techniques have been proposed.
Bacalbasa, Nicolae+6 more
core +1 more source
The retinoblastoma protein/p16INK4A pathway but not p53 is disrupted by human papillomavirus in penile squamous cell carcinoma [PDF]
Aims: The pathogenesis of penile squamous cell carcinoma (PSCC) is not well understood. Human papillomavirus (HPV) may be involved in carcinogenesis, but few studies have compared cell-cycle protein expression in HPV positive and negative cancers.
Backes+38 more
core +3 more sources
Objective To assess the prognostic value of the systemic immune-inflammation index (SII) in patients with vulvar cancer. Methods Data of 130 consecutive patients who underwent primary surgical resection for vulvar cancer at the Medical University of ...
T. Bartl+6 more
semanticscholar +1 more source
CACA guidelines for vulvar malignancies
Objective The purpose of this study is to provide reference and guidance for the clinical diagnosis and treatment of vulvar malignancies. Method This article sorts out and integrates the contents of vulvar malignancies in the field of traditional Chinese
Zhongqiu Lin+9 more
doaj +1 more source
Understanding genomic alterations in cancer genomes using an integrative network approach [PDF]
In recent years, cancer genome sequencing and other high-throughput studies of cancer genomes have generated many notable discoveries. In this review, Novel genomic alteration mechanisms, such as chromothripsis (chromosomal crisis) and kataegis (mutation storms), and their implications for cancer are discussed.
arxiv +1 more source
Data-integration with pseudoweights and survey-calibration: application to developing US-representative lung cancer risk models for use in screening [PDF]
Accurate cancer risk estimation is crucial to clinical decision-making, such as identifying high-risk people for screening. However, most existing cancer risk models incorporate data from epidemiologic studies, which usually cannot represent the target population.
arxiv
What's new? Patients with human papillomavirus (HPV)‐associated high‐grade vulvar intraepithelial lesion (HSIL) often undergo damaging treatments to prevent progression to cancer. Molecular characterization of HSIL to assess progression risk could reduce the need for aggressive interventions. Here, cancer risk stratification of HSIL was investigated by
Flavia Runello+8 more
wiley +1 more source