Results 11 to 20 of about 145,126 (195)

Expression pattern of class I histone deacetylases in vulvar intraepithelial neoplasia and vulvar cancer: a tissue microarray study [PDF]

BMC Cancer, 2011
Background Epigenetic regulation is an important mechanism leading to cancer initiation and promotion. Histone acetylation by histone deacetylases (HDACs) represents an important part of it.
Samartzis Nicolas, Imesch Patrick, Dedes Konstantin J, Samartzis Eleftherios P, Fedier André, Fink Daniel, Caduff Rosmarie, Fehr Mathias K   +7 more
doaj   +3 more sources

Unrecognized invasive carcinoma in vulvar intraepithelial neoplasia (VIN)

Gynecologic Oncology, 1988
Sixty-nine patients having had pretreatment biopsy diagnosis of vulvar intraepithelial neoplasia were treated with surgical excision of all visible lesions. Complete surgical specimens were submitted for pathological study in an attempt to identify occult invasive vulvar carcinoma. Unsuspected invasion was noted in 13 patients (18.8%).
Division of Gynecology Oncology, Department of Obstetrics and Gynecology, University of Florida College of Medicine, Gainesville, Florida 32610 U.S.A. ( host institution ), Chafe, Weldon, Richards, Audrey, Morgan, Linda, Wilkinson, Edward   +4 more
core   +5 more sources

Treatment Results of Vulvar Intraepithelial Neoplasia in 16 Women

Gynecology Obstetrics & Reproductive Medicine, 2008
OBJECTIVE: Clinical outcome after surgical treatment of vulvar intraepithelial neoplasia (VIN). STUDY DESIGN; 16 women with vulvar intraepithelial neoplasia were reviewed.
Cüneyt Eftal Taner, İrem Şenyuva, Şevki Göksun Gökulu   +2 more
doaj   +1 more source

Cervical and Vulvar Intraepithelial Neoplasia after Treatment with Oral Isotretinoin for Severe Acne Vulgaris

Case Reports in Dermatology, 2009
Oral isotretinoin is the drug of choice for severe acne vulgaris, but its use is still controversial in preventing, treating or stopping the progression of the cervical intraepithelial neoplasia [6–8].
M.N. Al Hallak, N. Zouain
doaj   +2 more sources

Virus del papil·loma humà com a factor pronòstic en les neoplàsies malignes de la vulva i de la vagina [PDF]

, 2012
[cat] El Virus del Papil•loma Humà (VPH) està implicat en la patogènesis dels tumors del tracte genital femení i es detecta en la pràctica totalitat dels carcinomes de cèrvix, considerant-se una causa necessària per al seu desenvolupament.
Fusté Chimisana, Maria Victòria
core   +6 more sources

Symptomatic Vulvar Primary Cutaneous Amyloidosis Associated With Low-Risk HPV: A Case Report. [PDF]

Clin Case Rep
ABSTRACT Primary localized cutaneous amyloidosis (PCLA) of the vulva is an infrequent diagnosis. Its clinical presentation may mimic neoplastic or inflammatory lesions and could even be associated with human papillomavirus (HPV) of low or high oncogenic risk, making accurate diagnosis and exclusion of systemic involvement essential. A 73‐year‐old woman
Hoegl J, Fernandes A, Marquez D, Silva Y.   +3 more
europepmc   +2 more sources

Depth of Invasion of 13 mm or Greater Accurately Predicted the Risk of Having a Node Positivity in Lymphadenectomy for Squamous Vulvar Cancer. [PDF]

J Obstet Gynaecol Res
ABSTRACT Aim To analyze factors related to lymph node involvement in patients with squamous vulvar cancer undergoing lymphadenectomy and wide local excision at the University Hospital in Campinas, Brazil. Methods A retrospective study involving 56 women treated between 2010 and 2022.
Albuquerque RC, Sousa SS, Tozatti GV, Boneto B, Torres JC, Vale DB.   +5 more
europepmc   +2 more sources

Use of p53 immunohistochemistry can improve diagnostic agreement for differentiated vulvar intraepithelial neoplasia (dVIN): an international reproducibility study. [PDF]

Histopathology
Differentiated vulvar intraepithelial neoplasia (dVIN) is a precancerous lesion that can resemble non‐dysplastic lesions histologically. In this study involving 24 pathologists from 8 countries, pattern‐based interpretation of p53 immunohistochemistry improved interobserver agreement for dVIN and reduced rates of ‘indefinite‐for‐dysplasia’ diagnoses ...
Dasgupta S, Van Rompuy AS, Bergeron C, Heller DS, Rush D, Plantier F, Scurry J, Roberts J, Bart J, Lambein K, Veprauskas K, Van de Vijver KK, Makkus LA, Kooreman L, Bleeker M, Mohamed MB, Selim MA, Alvarez MCR, Van Bockstal MR, Jean-Christophe N, Guzman P, Srinivasan R, Arora R, Ball R, Wilhelmus S, Koljenović S, van Kemenade FJ, Ewing-Graham PC.   +27 more
europepmc   +2 more sources

Recurrent herpes simplex virus mimicking vulvar carcinoma in patient with Human Immunodeficiency Virus: A case report

Gynecologic Oncology Reports, 2023
Patients with human immunodeficiency virus (HIV) are at increased risk for developing other gynecologic conditions, including herpes simplex virus (HSV) and vulvar intraepithelial neoplasia (VIN)/carcinoma.
Rachel McKean, Jennifer Wolf, Ting Ting Wong, Yong Mei Yin, Margaux J. Kanis   +4 more
doaj   +1 more source

Vulval premalignant lesions: a review article [PDF]

Obstetrics & Gynecology Science
Vulvar intraepithelial neoplasia (VIN) is a noninvasive squamous lesion that is a precursor of vulvar squamous cell cancer. Currently, no screening tests are available for detecting VIN, and a biopsy is performed to confirm the clinical diagnosis ...
Sumedha Gupta, Sana Ahuja, Dheer Singh Kalwaniya, Saritha Shamsunder, Shalu Solanki   +4 more
doaj   +1 more source