Results 31 to 40 of about 145,126 (195)

The First Human Vulvar Intraepithelial Neoplasia Cell Line with Naturally Infected Episomal HPV18 Genome

Viruses, 2022
Persistent infection with high-risk HPV leads to cervical cancers and other anogenital cancers and head and neck carcinomas in both men and women. There is no effective drug fortreating HPV infection and HPV-associated carcinomas, largely due to a lack ...
Ming Wu, Xiu Zhang, Yiyi Kang, Yaqi Zhu, Zhaoyu Su, Jun Liu, Wei Zhang, Hong Chen, Hui Li   +8 more
doaj   +1 more source

Coexisting High-grade Vulvar Intraepithelial Neoplasia (VIN) and Condyloma Acuminatum [PDF]

American Journal of Surgical Pathology, 2013
The majority of vulvar intraepithelial neoplasia (VIN) is high-grade and is related to high-risk human papillomavirus (HRHPV) (most commonly HPV 16). It is considered to be the precursor of HRHPV-related vulvar squamous cell carcinoma. Vulvar condyloma acuminatum is low-risk HPV (LRHPV)-related (most commonly types 6 and 11) and has virtually no risk ...
Kruti P, Maniar, Brigitte M, Ronnett, Russell, Vang, Anna, Yemelyanova   +3 more
openaire   +2 more sources

AKT1 loss correlates with episomal HPV16 in vulval intraepithelial neoplasia. [PDF]

, 2012
Anogenital malignancy has a significant association with high-risk mucosal alpha-human papillomaviruses (alpha-PV), particularly HPV 16 and 18 whereas extragenital SCC has been linked to the presence of cutaneous beta and gamma-HPV types. Vulval skin may
Harwood Catherine A., Carolyn R Byrne, Karin J Purdie, Byrne, CR, Ekeowa-Anderson, AL, Purdie, Karin J, Jeffrey M. Arbeit (159402), Karin J. Purdie (159384), Jeffrey M Arbeit, O'Shaughnessy Ryan F. L., Byrne Carolyn R., Ekeowa-Anderson Arucha L., Gibbon, K, Ekeowa-Anderson, Arucha L, Byrne, Carolyn R, O'Shaughnessy, RFL, Ryan F L O'Shaughnessy, O'Shaughnessy, RF, Harwood, CA, Purdie Karin J., Arbeit, Jeffrey M, Arucha L. Ekeowa-Anderson (159376), Harwood, Catherine A, Karen Gibbon, Arbeit Jeffrey M., Arucha L Ekeowa-Anderson, Gibbon, Karen, Karen Gibbon (159391), Catherine A. Harwood (159410), Purdie, KJ, Ryan F. L. O'Shaughnessy (159418), Catherine A Harwood, Arbeit, JM, Gibbon Karen, O\u27Shaughnessy, Ryan F. L., Carolyn R. Byrne (159397)   +35 more
core   +1 more source

The eight-year long-term follow-up on the effectiveness of the quadrivalent human papillomavirus vaccine in Chinese women 20-45 years of age

Human Vaccines & Immunotherapeutics, 2022
The quadrivalent human papillomavirus (4vHPV) vaccine has shown confirmative effectiveness in preventing HPV-related diseases among women and men around the globe. The phase III, randomized, double-blind efficacy study (Base study, NCT00834106) conducted
Chao Zhao, Yun Zhao, Jingran Li, Mingzhu Li, Yanyan Su, Xin Mi, Su Yi La Tu, Danhua Shen, Lihua Ren, Yanyan Li, Linhong Wang, Lihui Wei   +11 more
doaj   +1 more source

methylation markers for cancer risk prediction of vulvar intraepithelial neoplasia

, 2021
Current clinical and histological classifications are unable to determine the risk of vulvar squamous cell carcinoma (VSCC) in high-grade vulvar intraepithelial neoplasia (VIN), making prognostic biomarkers highly needed.
Steenbergen, Renske D. M., Thuijs, Nikki B., Duin, Sylvia, Barbara C. Snoek, Renske D. M. Steenbergen, Nikki B. Thuijs, Müjde Özer, Heideman, Danielle A. M., Daniëlle A. M. Heideman, Ozer, Mujde, van Beurden, Marc, van Splunter, Annina P., Sylvia Duin, Annina P. van Splunter, Maaike C. G. Bleeker, Marc van Beurden, Berkhof, Johannes, Özer, M. jde, Bleeker, Maaike C. G., Snoek, Barbara C., Johannes Berkhof   +20 more
core   +1 more source

Anogenital diseases associated with HPV infection [PDF]

Гинекология, 2015
The review examined the role of HPV in anogenital diseases. There are presented modern data on the prevalence of anal intraepithelial neoplasia (AIN), HPV infection of the anal region among women at risk (cervical intraepithelial neoplasia - CIN, vulvar -
V N Prilepskaya, N M Nazarova, L A Sulamanidze, O V Burmenskaya, D Yu Trofimov, S V Pavlovich   +5 more
doaj  

Unveiling a Dermatological Rarity: The Enigma of Vulvar Intraepithelial Neoplasia Grade III (HSIL) and the Role of p53 in Its Development

Biomedicines
Vulvar intraepithelial neoplasia, also known as VIN, is a non-invasive squamous lesion and precursor of squamous cell carcinoma (SCC) of the vulva. There is no screening test for vulvar intraepithelial neoplasia.
Piotr Brzeziński, Igor Feszak, Beatriz Di Martino Ortiz, Sylwia Feszak, Piotr Kawczak, Tomasz Bączek   +5 more
doaj   +1 more source

Photodynamic therapy for treatment of usual-type vulvar intraepithelial neoplasia: a case report and literature review

Journal of International Medical Research, 2019
Vulvar intraepithelial neoplasia (VIN) is a pre-malignant condition of the vulvar skin that is found in 50% to 70% of patients with vulvar squamous cell cancer and is regarded as a precursor of vulvar tumors.
Ruina Zhang, Li Wang
doaj   +1 more source

THE INFLUENCE OF THE THYROID GLAND ON THE DEVELOPMENT OF THE SCLEROSING HULL OF THE VULVA IN WOMEN OF REPRODUCTIVE AGE

Клінічна та профілактична медицина, 2022
Sclerosing lichen (SL) of the external genitalia is a chronic slowly progressive disease with pronounced focal atrophy of the skin of the perineum and visible mucous membranes of the vulva and has two main peaks of clinical manifestations: childhood and ...
V.V. Dunaevska, O.M. Savluk
doaj   +1 more source

Prognostic impact of anal cancer morphology on survival and local recurrence: A 20‐year regional cohort study

Colorectal Disease, Volume 28, Issue 7, July 2026.
Abstract Aim The relationship between macroscopic tumour morphology and clinical outcomes has previously been demonstrated for malignant melanoma and gastric cancers, but not for anal squamous cell cancer (ASCC). This study investigated the effect of the morphology of ASCC on oncological outcomes.
Alwin Puthiyakunnel Saji, Thomas Rackley, James Horwood, Rachel Hargest   +3 more
wiley   +1 more source