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Molecular Features of Preinvasive and Invasive Vulvar Neoplasms
Journal of Lower Genital Tract Disease, 2022Objectives Neoplasms arising from the vulva are uncommon and comprise various subtypes. Given the recent advancements in the molecular aspects of oncologic pathology and how they have impacted cancer treatment, an understanding of recent innovations in the molecular features of vulvar lesions is important.
Pratik Q, Deb, Debra S, Heller
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EPITHELIAL VULVAR NEOPLASMS AND THEIR CHANGING CLASSIFICATION
Seminars in Cutaneous Medicine and Surgery, 2015In recent years, there have been many changes in the classification scheme for squamous lesions of the vulva; this is primarily due to the assimilation of new scientific information into the diagnostic terminology. For example, over the past 75 years we have realized that precancerous and cancerous lesions of the vulva may be induced by a variety of ...
Russell, Ball +2 more
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A comparative study of MMP-2 in vulvar neoplasms
Gynecologic Oncology, 2004To investigate differences in MMP-2 protein expression in VIN, vulvar invasive carcinoma, and lichen sclerosus, we performed an immunohistochemical study in which tissue samples from individuals affected by these conditions were compared with normal vulvar tissue.A total of 57 cases were selected, as follows: 14 cases of vulvar invasive carcinoma, 22 ...
Bovo, A. C. +6 more
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Surgical Pathology Clinics, 2011
Carcinoma of the vulva is an uncommon malignant neoplasm (approximately one-fifth as frequent as cervical cancer) and represents 4% of all genital cancers in women. Approximately two-thirds of cases occur in women older than 60 years, and squamous cell carcinoma is the most common histologic type.
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Carcinoma of the vulva is an uncommon malignant neoplasm (approximately one-fifth as frequent as cervical cancer) and represents 4% of all genital cancers in women. Approximately two-thirds of cases occur in women older than 60 years, and squamous cell carcinoma is the most common histologic type.
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Prepubertal Vulvar Fibroma: Neoplasm or Physiological Condition? [PDF]
Journal of Pediatric and Adolescent Gynecology, 2016 Several authors have previously reconsidered vulvar fibroma, a rare prepubertal neoplasm, as a physiological labial asymmetry of early puberty, recommending a conservative approach for all cases, although some required further clarification.A fibrous mass found in the left labium majus of a 4-year-old girl was surgically removed.
Goldrat, Ornite +3 more
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Vulvar Glandular and Other Neoplasms
2019This chapter will address vulvar neoplasms with glandular differentiation as well as neuroendocrine carcinoma and metastatic tumors. These entities are rare, as the vast majority of malignancies of the vulva are squamous in origin. Careful consideration of the differential diagnosis, as well as knowledge of any pertinent clinical history, is essential ...
Andrew Dunn +2 more
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[Vulvar intraepithelial neoplasm].
Ginecologia y obstetricia de Mexico, 2006Vulvar intraepithelial neoplasia is a challenge for the physician as it is asymptomatic and it can evolve to malignant disease. A high suspicion index, as well as some biopsies are necessary, provided an early invasive disease can exist.To establish the patient's characteristics with vulvar intraepithelial neoplasia, seen at the Clinica de ...
María de los Angeles, Madrigal de la Campa +2 more
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A Histologic Review of Vulvar Inflammatory Dermatoses and Intraepithelial Neoplasm
Dermatologic Clinics, 2010Patients with urogenital complaints are frequently encountered by family practitioners, gynecologists, and dermatologists. This review article provides practical information regarding normal anatomy and embryology of the vulva, followed by a summary of procedural techniques.
Maria Angelica, Selim, Mai P, Hoang
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[Vulvar neoplasms and preoperative lymphography].
Fortschritte der Medizin, 197820 patients with histologically verified carcinoma of the vulva fulfilled the following conditions: general operability, preoperative lymphography, radical vulvectomy with inguinal lymph node resection and histological examination of all lymph nodes.
H G, Bender +3 more
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SMARCB1-deficient Vulvar Neoplasms
American Journal of Surgical Pathology, 2015Loss of expression of the SMARCB1 (INI1/BAF47/SNF5) tumor-suppressor protein, originally identified in pediatric malignant rhabdoid tumors, has been noted in significant percentages of epithelioid sarcomas of classical and proximal-type and in myoepithelial carcinomas.
Andrew L, Folpe +8 more
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