Results 101 to 110 of about 29,128,481 (331)

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Evolutionary state of W UMa-type systems

open access: yesAstrophysics and Space Science, 1992
The evolutionary status of a sample of 31 W UMa-type systems (20 of W, 9 of A, and 2 of A/W sub-class) is examined and discussed on the basis of their positions in the H-R, mass-radius and mass-luminosity diagrams. The absolute elements of these systems have been evaluated by use of their spectroscopic and photometric data as they were found in the ...
ROVITHISLIVANIOU, H   +2 more
openaire   +2 more sources

New signals in pair production of heavy Q=2/3 singlets at LHC [PDF]

open access: yes, 2006
New quark singlets T can be produced in pairs at LHC through standard QCD interactions, with a large cross section for masses of several hundreds of GeV. Their charged current decays T Tbar T -> W+ b W- bbar, with semileptonic decay of the W pair, give a
Aguilar-Saavedra, J. A.
core   +2 more sources

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Deuterium plasma-driven permeation in chemical vapor deposition tungsten-copper composite

open access: yesNuclear Fusion
With the potential application of tungsten (W)-copper (Cu) bonding in the plasma-facing components (PFCs) in fusion devices, hydrogen isotope (HI) transport through the W/Cu interface has become a key concern for tritium self-sustainment and operational ...
Yiwen Sun   +13 more
doaj   +1 more source

Community perceptions and factors influencing utilization of health services in Uganda

open access: yesInternational Journal for Equity in Health, 2009
Background Healthcare utilization has particular relevance as a public health and development issue. Unlike material and human capital, there is little empirical evidence on the utility of social resources in overcoming barriers to healthcare utilization
Galea Sandro   +5 more
doaj   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Effectiveness of Machine Learning in Predicting Orthodontic Tooth Extractions: A Multi-Institutional Study

open access: yesBioengineering
The study aimed to evaluate the effectiveness of machine learning in predicting whether orthodontic patients would require extraction or non-extraction treatment using data from two university datasets.
Lily E. Etemad   +8 more
doaj   +1 more source

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