Results 221 to 230 of about 1,024,017 (312)

Biomimetic Cell Membrane‐Coated MOFs System for Targeted Cancer Therapy

Advanced Science, EarlyView.
Biomimetic MOF‐based drug delivery nanoplatforms synthesized using liposomes or cell membranes as camouflage for multiple cancer therapeutics. ABSTRACT The integration of metal‐organic frameworks (MOFs) with cell membrane coatings has emerged as a revolutionary strategy to enhance the therapeutic efficacy of cancer nanomedicine.
Qilu Wu, Jia Song Deon Chon, Yuxiao Feng, Kang Liang, Shiming Li, Can Yang Zhang, Jun Ge   +6 more
wiley   +1 more source

Doxy-PEP interest, awareness, and use among sexual and gender minorities in Brazil, Mexico, and Peru: findings from a web-based survey. [PDF]

Lancet Reg Health Am
Silva MST, Luz PM, Konda KA, Veja-Ramirez H, Coutinho C, Qquellon J, Robles-Garcia R, Hoagland B, Jalil EM, Benedetti M, Pimenta C, Cardoso SW, Caceres CF, Veloso VG, Grinsztejn B, Torres TS.   +15 more
europepmc   +1 more source

Leveraging Artificial Intelligence and Large Language Models for Cancer Immunotherapy

Advanced Science, EarlyView.
Cancer immunotherapy faces challenges in predicting treatment responses and understanding resistance mechanisms. Artificial intelligence (AI) and machine learning (ML) offer powerful solutions for cancer immunotherapy in patient stratification, biomarker discovery, treatment strategy optimization, and foundation model development.
Xinchao Wu, Mengtao Sun, Lusheng Li, Jieqiong Wang, Shibiao Wan   +4 more
wiley   +1 more source

Job quality and employee happiness: evidence from China. [PDF]

Front Psychol
Yu B, Song Z, Shen Z.
europepmc   +1 more source

Dynamic Shifts in ER–Plasma Membrane Junctions Signaling Define Pro‐Metastatic N‐Glycosylation and Predict Prostate Cancer Progression

Advanced Science, EarlyView.
Prostate cancer remains a leading cause of male cancer death, yet screening cannot reliably identify aggressive disease, underscoring the need for tissue biomarkers. It is shown that primary tumors increase ER–plasma membrane junction signaling via STIM1/ORP5, whereas metastasis features their loss, Golgi dispersal, and rapid conversion of high‐mannose
Amanda J. Macke, Tania Kamal, Taylor E. Divita, Artem N. Pachikov, Chad A. LaGrange, Rajesh Ravichandran, Martha Morton, Robert Powers, Haowen Qiu, Jean‐Jack M. Riethoven, Colm Morrissey, Melinda Wojtkiewicz, Rebekah L. Gundry, Carol A. Casey, Armen Petrosyan   +14 more
wiley   +1 more source

A Rational Optimization Approach for the Development of a Multiplexed Lateral Flow Immunoassay: Detection of Nonepithelial Ovarian Cancer Markers in Human Serum

Advanced Science, EarlyView.
This study outlines the developmental pipeline of a multiplexed nanozyme‐based lateral flow immunoassay for the purpose of ovarian germ cell tumor detection. It demonstrates the application of a design of experiments optimization approach for nanozyme probe conjugate development.
Aida Abdelwahed, Carl E. Eskildsen, Luca Panariello, André Shamsabadi, Christy J. Sadler, Edmund H. Wilkes, Federico Galvanin, Yuxi Cheng, Sara Carvalho, Srdjan Saso, Molly M. Stevens   +10 more
wiley   +1 more source

The economic burden of COVID-19 premature mortality in Kuwait. [PDF]

BMC Public Health
Almari M, O'Neill S, Sadique Z.
europepmc   +1 more source

ML Workflows for Screening Degradation‐Relevant Properties of Forever Chemicals

Advanced Science, EarlyView.
The environmental persistence of per‐ and polyfluoroalkyl substances (PFAS) necessitates efficient remediation strategies. This study presents physics‐informed machine learning workflows that accurately predict critical degradation properties, including bond dissociation energies and polarizability.
Pranoy Ray, Andrew R. Castillo, Manoj Kolel‐Veetil, Surya R. Kalidindi   +3 more
wiley   +1 more source

Unions and employment of migrant workers in China: a causal analysis using the treatment effect model. [PDF]

Front Psychol
Guo Z, Yang M, Sun H.
europepmc   +1 more source

Rapid Room‐Temperature Synthesis of Te4+‐Doped Cs2ZrCl6 Vacancy‐Ordered Double Perovskites With Tunable Luminescence Triggered by Extreme Conditions for Advanced Optical Thermometry and Manometry

Advanced Science, EarlyView.
Through utilizing a proposed rapid room‐temperature precipitation method, the Te4+‐doped Cs2ZrCl6 vacancy‐ordered doubles with intense STE emission were synthesized. Via using the extreme conditions, i.e., temperature and pressure, stimulus, the luminescence properties of the resulting compounds are significantly modulated, endowing their promising ...
Zhiyu Pei, Yeshan Wu, Shuailing Ma, Tian Cui, Laihui Luo, Peng Du   +5 more
wiley   +1 more source