Results 241 to 250 of about 761,973 (302)

Early-life sleep disruption in Shank3-deficient rats: A preclinical model for autism-related sleep mechanisms and interventions. [PDF]

open access: yesTransl Psychiatry
Qiu MH   +9 more
europepmc   +1 more source

Endothermy, neuron counts, and other issues: Further remarks on neurocognitive evolution in fossil vertebrates

open access: yesThe Anatomical Record, EarlyView.
Abstract Last year, we challenged the view that large‐bodied theropod dinosaurs such as Tyrannosaurus rex resembled primates in cognition and behavior, a proposition made by Herculano‐Houzel in 2023. More recently, Jensen et al. have criticized our work on this topic, raising methodological and conceptual issues.
Kai R. Caspar   +5 more
wiley   +1 more source

Pharmacological and non-pharmacological methods of inducing wakefulness activate distinct neural populations in the mouse brain. [PDF]

open access: yesPLoS Biol
Maciel R   +8 more
europepmc   +1 more source

Zooarchaeological Analysis of an Atoll Assemblage From Central Micronesia

open access: yesArchaeology in Oceania, EarlyView.
ABSTRACT There has been a dearth of archaeological research on atolls in the central‐eastern Caroline Islands of Micronesia. This has limited our understanding of pre‐contact subsistence and settlement strategies in these more marginal and remote environments, particularly in regards to zooarchaeological data.
Philippa Jorissen   +2 more
wiley   +1 more source

Hepatotoxicity of Nonesterified Fatty Acids to Dairy Cows: Pathophysiological Mechanisms and Prospective Solutions

open access: yesAnimal Research and One Health, EarlyView.
Unregulated inflammation increases non‐esterified fatty acids (NEFAs), and triggers multi‐pathway hepatocyte damage including oxidative stress, mitochondrial dysfunction, and metabolic disorders in dairy cows. ABSTRACT Circulating concentrations of nonesterified fatty acids (NEFAs) are elevated due to lipid mobilization from adipose tissue in ...
Siqing Mao   +12 more
wiley   +1 more source

Inosine‐Triphosphate‐Pyrophosphatase Activity as a Potential Predictor of Methotrexate Remission in Juvenile Idiopathic Arthritis

open access: yesArthritis &Rheumatology, EarlyView.
Objective Methotrexate (MTX) is the first‐line therapy for juvenile idiopathic arthritis (JIA), but up to 40% of patients do not respond to it. Low inosine triphosphate pyrophosphatase (ITPA) activity has been associated with reduced clinical remission. We investigated the role and underlying mechanisms of ITPA in vitro. Methods ITPA enzymatic activity
Sofia Sindici Forgiarini   +19 more
wiley   +1 more source

Spontaneous spike-and-wave discharges during sleep in mice: circadian distribution and impact on sleep quality. [PDF]

open access: yesFront Neurol
Del Gallo F   +7 more
europepmc   +1 more source

Blended and digital approaches in histology and pathology teaching: A scoping review

open access: yesAnatomical Sciences Education, EarlyView.
Abstract Histology and pathology education is evolving, driven by the integration of digital microscopy with other technological advances. Gaining insight into the impact of this transition, while understanding the perspectives of both students and educators, is important for improving teaching practices. This includes mapping teaching methods, digital
Eleonora Nava   +3 more
wiley   +1 more source

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