Results 131 to 140 of about 29,026 (312)

A Toolkit for Targeted Neuromodulation of Striatal Direct Pathway Neurons Rescues Parkinsonian Motor Deficits in Mice

open access: yesAdvanced Science, EarlyView.
An adeno‐associated virus (AAV) toolkit enables selective anatomical and functional targeting of striatal D1‐MSNs through retrograde transduction. Enhanced capsids and engineered enhancers drive robust transgene expression across murine and primate models.
Zexuan Hong   +14 more
wiley   +1 more source

Predicting wind turbine blade loads using vorticity transport and RANS methodologies [PDF]

open access: yes, 2009
Two computational methods, one based on the solution of the vorticity transport equation, and a second based on the solution of the Reynolds-Averaged Navier-Stokes equations, have been used to simulate the aerodynamic performance of a horizontal axis ...
Fletcher, Timothy M.   +3 more
core   +1 more source

Stress History Establishes a Transient Tolerant State That Shapes Antibiotic Survival Upon Resuscitation

open access: yesAdvanced Science, EarlyView.
High‐throughput single‐cell analysis of resuscitating bacteria reveals a starvation‐history‐dependent transiently tolerant subpopulation that survives β$\beta$‐lactam exposure by temporarily reducing growth. Distinct from classical persisters, these actively growing yet dynamically modulated cells dominate survival across clinically relevant antibiotic
Kieran Abbott   +5 more
wiley   +1 more source

Miniaturized Bidirectional Thermal Stimulation System Integrated With an Electrode Array for Recording Neural Activities

open access: yesAdvanced Science, EarlyView.
This study presents a miniaturized bidirectional thermal stimulation system integrated with an electrode array enabling real‐time, bidirectional modulation and simultaneous recording of neural activity through localized heating and cooling. By monolithic integration of the Peltier element and with a silicon neural probe, the innovative system allows ...
Zoia Naumkina   +6 more
wiley   +1 more source

Improvement of a Free-Wake Model for the Aerodynamic and Aeroacoustic Analysis of a Small-Scale Two-Bladed Propeller in Hover

open access: yesAerospace
The aim of the present work is the improvement of a free-wake model for the analysis of a small-scale two-bladed propeller in hover. The simulations are carried out using a BEM approach implemented in the medium-fidelity solver RAMSYS.
Manuel Iannotta   +5 more
doaj   +1 more source

Vortex-induced vibration of catenary riser: reduced-order modeling and lock-in analysis using wake oscillator

open access: yes, 2009
A new reduced-order model capable of analyzing the vortex-induced vibration of catenary riser in the ocean current has been developed. This semi analytical-numerical approach is versatile and allows for a significant reduction in computational effort for
, KTP (Funder)   +5 more
core  

Turbulence in the wake of a roughness patch

open access: yes, 2012
Little research was done in the past concerning the propagation of three dimensional effect in shallow wake flow caused by a roughness patch. To get a better understanding of the consequences of the three dimensionality of the flow structures ...
Voermans, J.J. (Joey)
core   +1 more source

Personalized Network‐Guided Neuromodulation Enhances Human Working Memory

open access: yesAdvanced Science, EarlyView.
A personalized neuromodulation framework combining individualized functional brain network targeting with real‐time neural decoding is introduced. Using concurrent TMS–fMRI, participant‐specific stimulation targets and optimal frequencies are identified. Only optimal‐frequency stimulation improves working memory across sessions.
Ahsan Khan   +13 more
wiley   +1 more source

Development of a Prescribed Expanding Vortex Wake model for Horizontal Axis Wind Turbines

open access: yes, 2022
This work deals with an improvment to the Prescribe Vortex Wake (PVW) model, called Prescribed Expanding Vortex Wake (PEVW) model, which uses the Lifting Line theory in the description of the wind turbine blades and the vortex theory in modeling the ...
Antonini, Enrico Giuseppe Agostino
core  

Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing

open access: yesAdvanced Science, EarlyView.
Recent advances in smart nanotechnologies are expanding the toolbox for brain interfacing, from wireless neuromodulation and high‐resolution sensing to targeted delivery within the central nervous system. By combining responsive nanomaterials with bioinspired design, these platforms enable multimodal interactions with neurons and glia, while also ...
Tommaso Curiale   +6 more
wiley   +1 more source

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