Results 151 to 160 of about 95,143 (285)

Seizure classification using a multimodal seizure monitoring system (Nelli) in Dravet and Lennox–Gastaut syndromes: A non‐randomized, single‐center feasibility study

Epilepsia, EarlyView.
Abstract Objective This study aimed to assess the performance of the Nelli seizure monitoring system in detecting and classifying seizures during sleep or while at rest in bed in patients with Lennox–Gastaut syndrome (LGS) and Dravet syndrome (DS). Methods We conducted a non‐interventional, single‐center feasibility study from August 2023 to March 2024,
Line Kønig Wilms, Morten I. Lossius, Kaapo Annala, Jonas Abdel‐Khalik, Lena Fanter, Kaisa Elomaa, Jukka Peltola   +6 more
wiley   +1 more source

Pharmacogenetic Modulation of Orexin Neurons Alters Sleep/Wakefulness States in Mice

, 2011
Koh S, Mika Suzuki, Michihiro Mieda, Natsuko Tsujino, Bryan L. Roth, Takeshi Sakurai   +5 more
openalex   +2 more sources

Lennox–Gastaut syndrome unveiled: Advancing diagnosis, therapies, and advocacy‐insights from the Genoa International Workshop

Epilepsia, EarlyView.
Abstract Lennox–Gastaut syndrome (LGS) is one of the most severe, yet one of the most discussed, childhood‐onset developmental and epileptic encephalopathies (DEEs). Dissent among epileptologists on the definition and minimum set of electroclinical features derives from the high etiological heterogeneity within the syndrome, which could make its ...
Antonella Riva, Gianluca D'Onofrio, Elisabetta Amadori, Alexis Arzimanoglou, Stéphane Auvin, Irene Bagnasco, Paola Barabino, Valentina Biagioli, Isabella Brambilla, Giuliana Cangemi, Antonietta Coppola, Antonella De Lillo, Carlo Di Bonaventura, Giancarlo Di Gennaro, Edoardo Ferlazzo, Antonio Gil‐Nagel, Giuseppe Gobbi, Simona Lattanzi, Gerhard Kluger, Günter Krämer, Maria Margherita Mancardi, Carlo Minetti, Lino Nobili, Elisa Paravati, Milka Pringsheim, Erika Rebessi, Antonino Romeo, Angelo Russo, Emilio Russo, Katia Santoro, Susanne Schubert‐Bast, Laura Siri, Jo Sourbron, Maria Stella Vari, Alberto Verrotti, Flavio Villani, Maurizio Viri, Celina von Stülpnagel, Nelia Zamponi, Federico Zara, Pasquale Striano   +40 more
wiley   +1 more source

Septal Cholinergic Neuromodulation Tunes the Astrocyte-Dependent Gating of Hippocampal NMDA Receptors to Wakefulness

, 2017
Thomas Papouin, Jaclyn M. Dunphy, Michaela Tolman, Kelly T. Dineley, Philip G. Haydon   +4 more
openalex   +1 more source

Dynamical informational structures characterize the different human brain states of wakefulness and deep sleep [PDF]

, 2019
Javier A. Galadí, Silvana Silva Pereira, Yonatan Sanz Perl, Morten L. Kringelbach, I. Gayte, Helmut Laufs, Enzo Tagliazucchi, José A. Langa, Gustavo Deco   +8 more
openalex   +1 more source

Epilepsy in dentatorubral–pallidoluysian atrophy: A systematic review and meta‐analysis

Epilepsia, EarlyView.
Summary of key clinical and electrophysiological characteristics of DRPLA‐related epilepsy from a systematic review and meta‐analysis of 1,191 patients. DRPLA patients with epilepsy showed earlier disease onset, longer CAG repeat expansion, and a tendency toward paternal inheritance. EEG findings frequently included photoparoxysmal responses.
Toru Horinouchi, Haruka Ishibashi, Yukako Nakagami, Yoko Kobayashi Takahashi, Takato Akiba, Masaharu Miyauchi, Naohiro Yamamoto, Ryoichi Inoue, Satoshi Kodama, Takafumi Kubota, Naoto Kuroda   +10 more
wiley   +1 more source

Spike–fast activity interplay: A gateway to seizure

Epilepsia, EarlyView.
Abstract Objective The transition from interictal discharges to ictal high‐frequency activity (HFA) remains poorly understood. We investigated whether spike‐associated high‐frequency oscillations (Sp‐HFOs) during interictal and preictal periods contribute to the emergence of ictal HFA.
Thandar Aung, Aude Jegou, Patrick Chauvel   +2 more
wiley   +1 more source

EEG functional connectivity as a marker of evolution from infantile epileptic spasms syndrome to Lennox–Gastaut syndrome

Epilepsia, EarlyView.
Abstract Objective Timely diagnosis and effective treatment of Lennox–Gastaut syndrome (LGS) improve prognosis and lower health care costs, but the transition from infantile epileptic spasms syndrome (IESS) to LGS is highly variable and insidious. Objective biomarkers are needed to monitor this progression and guide clinical decision‐making. Methods We
Blanca Romero Milà, Virginia B. Liu, Rachel J. Smith, Derek K. Hu, Natalie A. Benneian, Shaun A. Hussain, Maija Steenari, Donald Phillips, David Adams, Clare Skora, Beth A. Lopour, Daniel W. Shrey   +11 more
wiley   +1 more source

Editorial: The Gating and Maintenance of Sleep and Wake: New Circuits and Insights

Frontiers in Neuroscience, 2020
Michael Lazarus, Yu Hayashi, Yu Hayashi, Sakiko Honjoh, Kaspar E. Vogt, Ada Eban-Rothschild, Qinghua Liu, Qinghua Liu, Qinghua Liu, Takeshi Sakurai   +9 more
doaj   +1 more source

Editorial: Neurobiology of sleeping behaviors

Frontiers in Behavioral Neuroscience, 2023
Emi Hasegawa, Emi Hasegawa, Emi Hasegawa, Yo Oishi, Yo Oishi, Daniel Kroeger, Tomomi Tsunematsu, Tomomi Tsunematsu, Yves Dauvilliers, Yves Dauvilliers   +9 more
doaj   +1 more source