Sex‐based disparities in dopamine agonist response in patients with restless legs syndrome
Journal of Sleep Research, Volume 34, Issue 2, April 2025.Summary This study aimed to investigate sex‐related differences in the response to ropinirole and pramipexole in patients with restless legs syndrome (RLS). By analysing clinical parameters and polysomnographic (PSG) findings, we sought to elucidate the potential factors related to sex disparities modulating treatment responses and sleep quality in RLS.
Maria P. Mogavero +9 more
wiley +1 more source
The Geometry of Layer 2/3 Cortical Sound Processing in Slow Wave Sleep. [PDF]
Adv Sci (Weinh)Muller A +3 more
europepmc +1 more source
Journal of Sleep Research, Volume 34, Issue 2, April 2025.Summary Boosting slow‐wave activity (SWA) by modulating slow waves through closed‐loop auditory stimulation (CLAS) might provide a powerful non‐pharmacological tool to investigate the link between sleep and neurodegeneration. Here, we established mouse CLAS (mCLAS)‐mediated SWA enhancement and explored its effects on sleep deficits in neurodegeneration,
Inês Dias +5 more
wiley +1 more source
Profiling the sleep architecture of ageing adults using a seven‐state continuous‐time Markov model
Journal of Sleep Research, Volume 34, Issue 2, April 2025.Summary Sleep is a complex biological process regulated by networks of neurons and environmental factors. As one falls asleep, neurotransmitters from sleep–wake regulating neurones work in synergy to control the switching of different sleep states throughout the night. As sleep disorders or underlying neuropathology can manifest as irregular switching,
Jonathon Jacobs +3 more
wiley +1 more source
Orexin Receptor Antagonism Improves Sleep Quality and Mitigates Lipopolysaccharide-Induced Inflammatory Responses in a Mouse Model. [PDF]
FASEB JHoriuchi D +7 more
europepmc +1 more source
Decrease of excessive daytime sleepiness after shunt treatment for normal pressure hydrocephalus
Journal of Sleep Research, Volume 34, Issue 2, April 2025.Summary Sleepiness and apathy are often reported in patients with normal pressure hydrocephalus. However, research on outcomes after shunt surgery has mainly focused on the classical triad symptoms, that is, gait, cognition, and bladder dysfunction. This study aimed to describe the effects of shunt treatment on excessive daytime sleepiness and whether ...
Simon Lidén +4 more
wiley +1 more source
Motivation meets sleep: tuning arousal via nucleus accumbens and Basal Ganglia circuits. [PDF]
NPJ Biol Timing SleepSayegh FJP, Bonnavion P.
europepmc +1 more source
Journal of Sleep Research, Volume 34, Issue 2, April 2025.Lemborexant 10 mg, a dual orexin‐receptor antagonist (DORA), did not elicit respiratory depressant effects, as measured by peripheral oxygen saturation (SpO2) or apnea–hypopnea index (AHI), in subjects with moderate‐to‐severe chronic obstructive pulmonary disease (COPD).
Jocelyn Y. Cheng +3 more
wiley +1 more source
Obstructive sleep apnea increases heartbeat-evoked potentials and reorganizes Granger-causal coupling between cortical interoception and autonomic variability during wakefulness. [PDF]
Sci RepAlidadi M +3 more
europepmc +1 more source
Journal of Sleep Research, Volume 34, Issue 2, April 2025.Summary Dreaming, a common yet mysterious cognitive phenomenon, is an involuntary process experienced by individuals during sleep. Although the fascination with dreams dates back to ancient times and gained therapeutic significance through psychoanalysis in the early twentieth century, its scientific investigation only gained momentum with the ...
Carlotta Mutti +2 more
wiley +1 more source