Results 151 to 160 of about 44,355 (296)

Changes in cortical delta power during chronic invasive epilepsy monitoring

Epilepsia, EarlyView.
Abstract Objective Cortical delta band (1–4 Hz) activity is considered a biomarker for states of altered consciousness, with increased delta power observed during anesthesia, sleep, coma, and delirium. The current study sought to characterize delta power following electrode implantation with respect to patient demographics and clinical characteristics ...
Emily R. Dappen, Bryan M. Krause, Rashmi N. Mueller, Matthew I. Banks, Kirill V. Nourski   +4 more
wiley   +1 more source

Pupil constrictions to subjective brightness as a gateway to probe consciousness in non communicating patients. [PDF]

Sci Rep
Sangare A, Eymond C, Jodaitis L, Demeret S, Rohaut B, Naccache L.   +5 more
europepmc   +1 more source

Orexin/Hypocretin: Wired for Wakefulness [PDF]

, 2003
Takatoshi Mochizuki, Thomas E. Scammell
openalex   +1 more source

The human photosensitive epilepsy model for clinical proof‐of‐principle trials of novel antiseizure medications. 1. Use of the EEG in drug development and characteristics of the model

Epilepsia, EarlyView.
Abstract Clinical development of novel antiseizure medications (ASMs) would benefit from an early proof‐of‐principle (POP) model. The photosensitivity model, which uses the photoparoxysmal electroencephalography (EEG) response (PPR) as a surrogate for seizures, is currently the only human model that allows POP trials of investigational compounds after ...
Dorothée Kasteleijn‐Nolst Trenité, Wolfgang Löscher   +1 more
wiley   +1 more source

Changes in Body Temperature and Sleep‐Wakefulness AfterIntrapreoptic Injection of Methoxamine in Rats [PDF]

, 2003
Ra. Vetrivelan, Hruda Nanda Mallick, Velayudhan Mohan Kumar   +2 more
openalex   +1 more source

What Keeps Us Awake: the Neuropharmacology of Stimulants and Wakefulness Promoting Medications [PDF]

, 2004
Benjamin Boutrel, George F. Koob
openalex   +1 more source

Asymmetry of generalized discharges in idiopathic generalized epilepsy in adults

Epilepsia, EarlyView.
Abstract Generalized epileptiform discharges (GEDs) in idiopathic generalized epilepsy (IGE) are classically considered symmetrical in amplitude, although this has not been formally tested. This is a major knowledge gap, since asymmetry is conventionally considered an atypical feature, with clinical implications.
Joao Pizarro, Matthew C. Walker, Laurent Sheybani   +2 more
wiley   +1 more source

Laboratory-induced extended wakefulness impairs mood and vigilance but not gambling behaviour in regular gamblers. [PDF]

Sci Rep
Thorne HB, Rockloff M, Vincent GE, Browne M, Ferguson SA.   +4 more
europepmc   +1 more source

Interactions between GABAergic and Cholinergic Processes in the Nucleus Pontis Oralis: Neuronal Mechanisms Controlling Active (Rapid Eye Movement) Sleep and Wakefulness [PDF]

, 2004
Ming-Chu Xi, Francisco R. Morales, Michael H. Chase   +2 more
openalex   +1 more source

Neuronal oscillatory imbalances in GNAO1‐related disorders associated with disease severity

Epilepsia, EarlyView.
Abstract Objective This study investigates excitatory/inhibitory (E/I) imbalances in GNAO1‐related disorders (GNAO1‐RD), linking neuronal dysfunction to clinical severity using E/I‐sensitive electroencephalography (EEG) analyses. Methods We conducted an observational study involving 12 children with GNAO1‐RD caused by pathogenic variants and 36 age ...
Tongyu Wang, Jana Domínguez‐Carral, William Grant Ludlam, Mar Junyent Segarra, Montserrat Fornaguera Marti, Hilgo Bruining, Kirill A. Martemyanov, Klaus Linkenkaer‐Hansen, Juan Dario Ortigoza‐Escobar   +8 more
wiley   +1 more source