Results 201 to 210 of about 92,257 (361)

Lateralizing value of interictal epileptiform discharges and other parameters in hypothalamic hamartoma

Epilepsia, Volume 66, Issue 3, Page 662-673, March 2025.
Abstract Objective Hypothalamic hamartomas (HHs) are associated with pharmacoresistant epilepsy. Stereotactic radiofrequency thermocoagulation (SRT) shows promise as a disconnecting intervention. Although magnetic resonance imaging (MRI) is typically used to determine the attachment and intervention side, it presents challenges in cases of bilaterally ...
Friederike Niedermoser, Sarah M. Metzger, Kathrin Wagner, Peter C. Reinacher, Jan Schönberger, Julia Jacobs‐LeVan, Andreas Schulze‐Bonhage, Kerstin Alexandra Klotz   +7 more
wiley   +1 more source

Rare dysfunctional SCN2A variants are associated with malformation of cortical development

Epilepsia, Volume 66, Issue 3, Page 914-928, March 2025.
Abstract Objective SCN2A encodes the voltage‐gated sodium (Na+) channel α subunit NaV1.2, which is important for the generation and forward and back propagation of action potentials in neurons. Genetic variants in SCN2A are associated with a spectrum of neurodevelopmental disorders.
Jérôme Clatot, Christopher H. Thompson, Susan Sotardi, Jinan Jiang, Marina Trivisano, Simona Balestrini, D. Isum Ward, Natalie Ginn, Brunetta Guaragni, Laura Malerba, Angeliki Vakrinou, Mia Sherer, Ingo Helbig, Ala Somarowthu, Sanjay M. Sisodiya, Roy Ben‐Shalom, Renzo Guerrini, Nicola Specchio, Alfred L. George Jr, Ethan M. Goldberg   +19 more
wiley   +1 more source

Editorial: The Gating and Maintenance of Sleep and Wake: New Circuits and Insights

Frontiers in Neuroscience, 2020
Michael Lazarus, Yu Hayashi, Yu Hayashi, Sakiko Honjoh, Kaspar E. Vogt, Ada Eban-Rothschild, Qinghua Liu, Qinghua Liu, Qinghua Liu, Takeshi Sakurai   +9 more
doaj   +1 more source

Sleep, recovery, and metaregulation: explaining the benefits of sleep

Nature and Science of Sleep, 2015
Vladyslav V VyazovskiyDepartment of Physiology, Anatomy, and Genetics, University of Oxford, Oxford, UKAbstract: A commonly held view is that extended wakefulness is causal for a broad spectrum of deleterious effects at molecular, cellular, network ...
Vyazovskiy VV
doaj  

A new perspective on drug‐resistant epilepsy in children with focal cortical dysplasia type 1: From challenge to favorable outcome

Epilepsia, Volume 66, Issue 3, Page 632-647, March 2025.
Abstract Objective We comprehensively characterized a large pediatric cohort with focal cortical dysplasia (FCD) type 1 to expand the phenotypic spectrum and to identify predictors of postsurgical outcomes. Methods We included pediatric patients with histopathological diagnosis of isolated FCD type 1 and at least 1 year of postsurgical follow‐up.
Barbora Splitkova, Katerina Mackova, Miroslav Koblizek, Zuzana Holubova, Martin Kyncl, Katerina Bukacova, Alice Maulisova, Barbora Straka, Martin Kudr, Matyas Ebel, Alena Jahodova, Anezka Belohlavkova, Gonzalo Alonso Ramos Rivera, Martin Hermanovsky, Petr Liby, Michal Tichy, Josef Zamecnik, Radek Janca, Pavel Krsek   +18 more
wiley   +1 more source

Effects of aerobic exercise training on heart rate variability during wakefulness and sleep and cardiorespiratory responses of young and middle-aged healthy men [PDF]

, 2002
Aparecida Maria Catai, Mara Patrícia Traina Chacon‐Mikahil, Federico Martinelli, V A M Forti, E. Silva, Roseli Golfetti, L. E. B. Martins, J S Szrajer, J S Wanderley, Euclydes C. Lima-Filho, Luís Aparecido Milan, José Antônio Marin‐Neto, Benedito Carlos Maciel, Lourenço Gallo‐Júnior   +13 more
openalex   +1 more source

When patients with Creutzfeldt–Jakob disease are misdiagnosed as having nonconvulsive status epilepticus

Epilepsia, Volume 66, Issue 4, Page 1006-1013, April 2025.
Abstract Contemporary studies report nonconvulsive status epilepticus (NCSE) in Creutzfeldt–Jakob disease (CJD), based on benzodiazepine (BZP)‐responsive epileptiform discharges on the electroencephalogram (EEG), with the following false syllogism: (1) intravenous (IV) administration of BZPs usually suppress ictal activity in NCSE; (2) in CJD, periodic
Philippe Gélisse, Arielle Crespel
wiley   +1 more source

The cerebellum in epilepsy

Epilepsia, EarlyView.
Abstract The cerebellum, a subcortical structure, is traditionally linked to sensorimotor integration and coordination, although its role in cognition and affective behavior, as well as epilepsy, is increasingly recognized. Cerebellar dysfunction in patients with epilepsy can result from genetic disorders, antiseizure medications, seizures, and seizure‐
Christopher Elder, Rebecca Kerestes, Puneet Opal, Maria Marchese, Orrin Devinsky   +4 more
wiley   +1 more source

Laboratory-induced extended wakefulness impairs mood and vigilance but not gambling behaviour in regular gamblers. [PDF]

Sci Rep
Thorne HB, Rockloff M, Vincent GE, Browne M, Ferguson SA.   +4 more
europepmc   +1 more source

Wakefulness is governed by GABA and histamine co-transmission [PDF]

, 2015
Brickley, SG, Franks, NP, Houston, CM, Ma, Y, Parker, S, Uygun, DS, Vyssotski, AL, Wisden, W, Yu, X, Yustos, Y, Zecharia, AY, Zhang, Z, Zhiwen, Y   +12 more
core   +1 more source