Results 71 to 80 of about 55,000 (288)
Frontiers in Neuroscience, 2019 Histone methylation/demethylation plays an important modulatory role in chromatin restructuring, RNA transcription and is essential for controlling a plethora of biological processes.
Eric Murillo-Rodríguez +23 more
doaj +1 more source
Does the 1/f frequency-scaling of brain signals reflect self-organized critical states?
, 2006 Many complex systems display self-organized critical states characterized by 1/f frequency scaling of power spectra. Global variables such as the electroencephalogram, scale as 1/f, which could be the sign of self-organized critical states in neuronal ...
A. Destexhe +19 more
core +1 more source
Integrating Astrocytes in the Sleep–Wake Cycle: The Time Is Now
BioEssays, EarlyView.Astrocytes actively regulate sleep homeostatic and circadian rheostatic processes, underpinning the sleep–wake cycle. By acting as context‐dependent integrators of internal state and rhythmic environmental inputs, they modulate the encoding properties of neuronal circuitries and contribute to salient temporal representations in the brain.
Marco Brancaccio
wiley +1 more source
Etiology and Neuropathophysiology of Coma
Türk Nöroloji Dergisi, 2012 Awareness and wakefulness require an intact connection of the neocortex with the ascending reticular formation. Any factor disrupting these pathways is likely to cause a syndrome of unconciousness. Disorders of consciousness encompass a broad spectrum of
Aslı Kıyat Atamer, Yakup Krespi
doaj +1 more source
Zebrafish: A Versatile and Powerful Model for Biomedical Research
BioEssays, EarlyView.Zebrafish are vital for advancing precision medicine, offering a genetically tractable and optically transparent vertebrate model with strong genetic homology to humans. They enable rapid and cost‐effective disease modeling and drug discovery, accelerating insights into cardiovascular, neurological, metabolic, and oncological disorders through gene ...
Sundus Siddiqui +3 more
wiley +1 more source
Frontiers in PsychiatryIntroductionThis study aimed to investigate the role of TAAR2-9 in sleep/wake regulation, given TAAR1's known involvement in modulating neurotransmitter release and sleep patterns.MethodsMale TAAR2-9 knockout (KO) and wild-type (WT) mice were compared ...
Sunmee Park +8 more
doaj +1 more source
Sleep dysfunction and EEG alterations in mice overexpressing alpha-synuclein. [PDF]
, 2014 BackgroundSleep disruptions occur early and frequently in Parkinson's disease (PD). PD patients also show a slowing of resting state activity. Alpha-synuclein is causally linked to PD and accumulates in sleep-related brain regions.
Chesselet, Marie-Françoise +3 more
core
Lighting as a Circadian Rhythm-Entraining and Alertness-Enhancing Stimulus in the Submarine Environment [PDF]
, 2006 The human brain can only accommodate a circadian rhythm that closely follows 24 hours. Thus, for a work schedule to meet the brain’s hard-wired requirement, it must employ a 24 hour-based program.
Bullough, J. D. +4 more
core +1 more source
Clinical Pharmacology &Therapeutics, EarlyView.Selective N‐methyl‐D‐aspartate receptor subunit 2b negative allosteric modulators (NR2B NAMs) are being explored as potential new treatment options for major depressive disorder (MDD). This Phase Ib, randomized, double‐blind, placebo‐controlled, parallel‐group trial was conducted in adults (N = 59) with moderate‐to‐severe MDD and insufficient response ...
Roger S. McIntyre +9 more
wiley +1 more source
Wakes in inhomogeneous plasmas [PDF]
Physical Review E, 2014 The Debye shielding of a charge immersed in a flowing plasma is an old classic problem in plasma physics. It has been given renewed attention in the last two decades in view of experiments with complex plasmas, where charged dust particles are often levitated in a region with strong ion flow.
Kompaneets, R. +3 more
openaire +4 more sources