Results 191 to 200 of about 2,957,243 (305)

Relationship between continuous infusion meropenem PK/PD target attainment and C‐reactive protein dynamics in onco‐haematologic patients with febrile neutropenia

British Journal of Clinical Pharmacology, EarlyView.
Aim Meropenem is a second‐line antimicrobial agent in the treatment of febrile neutropenia in onco‐haematological patients. A population pharmacokinetic/pharmacodynamic (PK/PD) analysis for assessing the relationship between meropenem exposure and C‐reactive protein (C‐RP) over time was conducted.
Chun Liu, Pier Giorgio Cojutti, J. G. Coen van Hasselt, Michele Bartoletti, Maddalena Giannella, Pierluigi Zinzani, Pierluigi Viale, Federico Pea   +7 more
wiley   +1 more source

Behavioral Profiles of Exam Stress: Mapping Student Diet, Sleep, and Substance Use. [PDF]

Nutrients
Butucaru AS, Mihăianu IG, Iorga M, Șipoș LR, Slăvescu DA, Iurcov ROC.   +5 more
europepmc   +1 more source

Clozapine:norclozapine ratio as a marker of metabolic risk and therapeutic response and effect of valproate on clozapine levels

British Journal of Clinical Pharmacology, EarlyView.
Aims Clozapine is the most effective antipsychotic in treatment‐resistant schizophrenia. Clozapine causes weight gain and increased diabetes risk. The role of its metabolite norclozapine and clozapine:norclozapine ratio (CLZ/NCLZ) in metabolic effects has been debated.
Susanna Maria Rask, Miina Lamminmäki, Olli Kampman, Mari Hämäläinen, Eeva Moilanen, Niko Seppälä, Anssi Solismaa   +6 more
wiley   +1 more source

Pulsatility index is a prognostic marker of cognitive outcome in patients with transient ischemic attack and mild acute stroke. [PDF]

Cereb Circ Cogn Behav
Brunelli N, Altamura C, Marcosano M, Vico C, Bach-Pages M, d'Onofrio L, Rossi SS, Costa CM, Sacco S, Silvestrini M, Vernieri F.   +10 more
europepmc   +1 more source

A Note on the Efficiency of the Wald Sequential Test

The Annals of Mathematical Statistics, 1947
openaire   +2 more sources

Dose‐related propofol resistance in COVID‐19 patients: Altered drug plasma levels, mechanistic insights from neuronal‐derived extracellular vesicles and miRNA analysis

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Critical care for COVID‐19 patients presents unique challenges, particularly in sedation management. Patients demonstrate notable dose‐related resistance to propofol, potentially due to complex pharmacokinetic alterations. Emerging evidence suggests that plasma extracellular vesicle‐associated miRNA represents valuable predictive ...
Debora Curci, Carlotta Bidoli, Marco Gerdol, Charisse Winston, Robert A. Rissman, Giuliana Decorti, Antonella Fabretto, Andrea Taddio, Gabriele Stocco, Erik Roman‐Pognuz, Marianna Lucafò   +10 more
wiley   +1 more source

Effective methods for increasing levels of political self‐efficacy for girls and disadvantaged students in England

British Educational Research Journal, EarlyView.
Abstract This study addresses the gap in rigorous evaluation of inclusive Citizenship Education methods in reducing gender and socioeconomic inequalities in political self‐efficacy. This article tests the effectiveness of two pedagogical approaches: counter‐narratives and think‐pair‐share.
Bryony Hoskins, Khuyen Dinh, Christian Christrup Kjeldsen   +2 more
wiley   +1 more source

Metabolic plasticity supports a flexible nutritional symbiosis in Cardiocondyla ants. [PDF]

Nat Commun
Cunningham P, Martín-Durán JM, Oettler J, Schultner E, Halitschke R, Engl T, Kaltenpoth M, Henry LM.   +7 more
europepmc   +1 more source

Occupational recognition and teachers’ retention intentions: A latent profile analysis informed by recognition theory

British Educational Research Journal, EarlyView.
Abstract Teacher retention is often explained through workload, job satisfaction and burnout, but these accounts have examined less systematically whether teachers experience their profession as socially and institutionally recognised. Drawing on recognition theory, this study examines how occupational recognition is configured across material and ...
Mengting Qian, Yufei Fang, Chunshun Yan, Yangxi Liu   +3 more
wiley   +1 more source

Group sequential clinical trial designs for composite endpoints incorporating recurrent and terminal events. [PDF]

Biometrics
Lian Q, Ahn KW, Kim S, Logan BR, Solh M, Martens MJ.   +5 more
europepmc   +1 more source