Results 41 to 50 of about 6,236 (223)

Clonal identification and homology differentiate primary central nervous system lymphoma from non-central nervous system lymphoplasmacytic lymphoma: a case report

Journal of Medical Case Reports
Background Lymphoplasmacytic lymphoma/Waldenström macroglobulinemia rarely transforms into diffuse large B-cell lymphoma, and there have been no reports of cases proving clonal identity when presenting as primary central nervous system lymphoma.
Yuko Tanaka, Nahoko Furuya, Seiichi Okabe, Seiichiro Yosizawa, Seiichiro Katagiri, Michiyo Asano, Tamiko Suguro, Mitsuru Moriyama, Akiko Yamada, Shunsuke Ohtsuki, Hiroaki Fujimoto, Daigo Akahane, Moritaka Gotoh, Maki Tanigawa, Jun Matubayashi, Shinjiro Fukami, Michihiro Kohno, Toshitaka Nagao, Naoya Nakamura, Akihiko Gotoh   +19 more
doaj   +1 more source

Macroglobulinemia de Waldenström con transformación a Linfoma del manto

Galicia Clínica, 2013
La Macroglobulinemia de Waldenström (MW) es una enfermedad infrecuente con una incidencia de tres casos por millón de habitantes al año aproximadamente1 y cuyo diagnóstico siempre plantea importantes dudas.
M. Martínez Gabarrón, J.J Castellanos Monedero, M.A. Galindo Andúgar, A. Martín Castillo   +3 more
doaj   +1 more source

Lymphoplasmacytic lymphoma relapse presenting as isolated multifocal subcutaneous adipose tissue infiltrates on 18F-FDG PET/CT

Acta Radiologica Open, 2023
Lymphoplasmacytic lymphoma (LPL)/Waldenström macroglobulinemia (WM) is an uncommon mature B cell lymphoma usually involving the bone marrow and, less commonly, the spleen and/or lymph nodes.
Saša Anžej Doma, Andrej Doma
doaj   +1 more source

Long-term survival in multiple myeloma is associated with a distinct immunological profile, which includes proliferative cytotoxic T-cell clones and a favourable Treg/Th17 balance [PDF]

, 2013
Despite improved outcomes in multiple myeloma (MM), a cure remains elusive. However, even before the current therapeutic era, 5% of patients survived >10 years and we propose that immune factors contribute to this longer survival.
Aklilu, E, Brown, R, Bryant, C, Favaloro, J, Fromm, P, Gibson, J, Hart, D, Ho, P, Iland, H, Joshua, D, Nassif, N, Suen, H, Woodland, N, Yang, S   +13 more
core   +2 more sources

Treatment for Waldenstrom’s macroglobulinemia

Annals of Oncology, 2004
Waldenstrom's macroglobulinemia is a rare form of indolent lymphoma characterized by the production of a monoclonal immunoglobulin M protein, and complications such as hyperviscosity, cytopenias and peripheral neuropathy. Conventional treatment approaches are based on alkylators or nucleoside analogs, but in the absence of a clearly superior regimen, a
openaire   +2 more sources

Loncastuximab Tesirine in Relapsed/Refractory Diffuse Large B‐Cell Lymphoma: Evidence and Practical Guidance From Italian Clinical Experience

European Journal of Haematology, Volume 117, Issue 1, Page 144-153, July 2026.
ABSTRACT Patients with relapsed/refractory (R/R) diffuse large B‐cell lymphoma (DLBCL) who progress to the third‐line setting face a lack of standardized treatment, despite the presence of multiple available therapies. In this context, antibody–drug conjugates represent a relatively new class of anticancer agents; among them, loncastuximab tesirine is ...
Francesca Bonello, Andrea Aroldi, Alessia Castellino, Lara Mannelli, Elia Boccellato, Serena Rosati, Luisa Verga, Umberto Vitolo   +7 more
wiley   +1 more source

Cutaneous amyloidosis as the first presentation of Waldenstrom macroglobulinemia

Caspian Journal of Internal Medicine, 2020
Background: Waldenstrom macroglobulinemia is a lymphoplasmacytic lymphoma with elevated serum immunoglobulin M and multi-organ involvement. Primary systemic amyloidosis usually develops due to immunoglobulin light chains depositions in different organs ...
Rana Rafiei, Hojat Eftekhari, Behnam Rafiee   +2 more
doaj  

Increased glutathione utilization augments tumor cell proliferation in Waldenstrom Macroglobulinemia

Redox Biology, 2020
Metabolic reprogramming is a hallmark of cancer cells. In Waldenstrom Macroglobulinemia (WM), the infiltration of IgM-secreting lymphoplamacytic cells into the bone marrow (BM) could shift the homeostasis of proteins and metabolites towards a permissive ...
Shahrzad Jalali, Jie Shi, Alex Buko, Nagib Ahsan, Jonas Paludo, Makayla Serres, Linda E. Wellik, Jithma Abeykoon, HyoJin Kim, Xinyi Tang, Zhi-Zhang Yang, Anne J. Novak, Thomas E. Witzig, Stephen M. Ansell   +13 more
doaj   +1 more source

Bone Marrow Pathology in Cold Agglutinin‐Mediated Autoimmune Hemolytic Anemia: A Study of 56 Cases

European Journal of Haematology, EarlyView.
ABSTRACT Cold agglutinin disease (CAD) is a rare form of autoimmune hemolytic anemia (AIHA). CAD occurs in the context of a small clonal B‐cell lymphoproliferation restricted to blood and/or bone marrow (BM), without overt or extramedullary lymphoma. The WHO‐HAEM5 introduced a description of the CAD‐associated lymphoproliferative disorder (CAD‐LPD) in ...
Anne‐Marie L. Becking, Sophie J. Bernelot Moens, Marie José Kersten, Femke V. M. Mulder, Steven T. Pals, Lianne Koens, Josephine M. I. Vos   +6 more
wiley   +1 more source

Current approach to Waldenström Macroglobulinemia

Cancer Treatment and Research Communications, 2022
Waldenström Macroglobulinemia (WM) is a unique, low grade, IgM lymphoplasmacytic lymphoma with a heterogeneous clinical course. A paucity of high-grade evidence from large phase 3 trials remains a major issue in the field despite a rapidly expanding ...
Gayathri Ravi, Prashant Kapoor
doaj   +1 more source