Results 121 to 130 of about 106,987 (300)

Oxygen Vacancy‐Enriched Platinum Single‐Atom Nanozyme Wrapped in Nanoislands: Unlocking Catalytic Activity and Reprogramming Redox Microenvironment for Osteonecrosis Repair

Advanced Science, EarlyView.
CeO2‐x/Pt single‐atom nano‐island is constructed via low‐temperature reduction, featuring abundant oxygen vacancies and an island–sea structure. It delivers outstanding multi‐enzyme‐mimetic activity and ROS‐scavenging efficiency. Density functional theory reveals optimized electronic structures and reaction pathways.
Yang Zhu, Zehui Lv, Xuejie Cai, Penghui Wei, Dengliang Wang, Zhao Wang, Ruoying Wang, Yingjie Wang, Xingdong Yang, Yixin Bian, Jiawei Xu, Xisheng Weng, Liangfeng Wei   +12 more
wiley   +1 more source

A Brain‐Penetrant Nanobody Reveals GSK3β‐Driven Proline‐Directed Phosphorylation as a Master Regulator of Ischemic Neurodegeneration

Advanced Science, EarlyView.
A brain‐targeted nanoparticle enables delivery of a therapeutic nanobody (Nb.29E9) that inhibits pathogenic GSK3β signaling. This intervention restores AMPK/mTORC1/TGFβ homeostasis, attenuates neuroinflammation and oxidative stress, and promotes long‐term functional recovery after ischemic stroke.
Lan Li, Muyang Li, Lei Sun, Ying Yang, Yuanshun Wu, Ziyi Yin, Anni Wang, Peiyang Zhou, Shaoxiang Luo, Jian Chen, Jun Qin, Zhibing Ai, Zilong Yuan, Zhiqiang Dong, Min Zhang   +14 more
wiley   +1 more source

Generation of Self‐Organizing Macrovascular Constructs by Bioprinting Human iPSC‐Derived Mesodermal Progenitor Cells

Advanced Science, EarlyView.
ABSTRACT Vascularization remains a major obstacle in tissue engineering. Here, we introduce a bioprinting strategy to generate centimeter‐scale, self‐organizing “mother vessel” constructs from iPSC‐derived hiMPCs. By optimizing bioink composition, printing was accomplished in a single‐step approach. Within one week, hiMPCs differentiated into both CD31+
Leyla E. Dogan, Nathaly A. Chicaiza‐Cabezas, Florian Kleefeldt, Philipp Wörsdörfer, Jürgen Groll, Süleyman Ergün   +5 more
wiley   +1 more source

Christ Walking on Water

Detail Disciples in Boat, LandscapeJesus walking on the water (Miracle ...
Witz, Konrad, Witz, Konrad, ca. 1400-ca. 1445   +1 more
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Cardiovascular system response to therapeutic water treadmill walking in older adults /

, 2005
Director: Jennifer L. Caputo.Because older adults have a greater propensity toward musculoskeletal problems, aquatic exercise is a valuable modality for rehabilitation and physical training.
Dolbow, David
core   +1 more source

Impacts of water depth on pedestrian speed, gait, and stability: results from an experimental study

Acta Polytechnica CTU Proceedings
Under rapid socio-economic development and increasingly frequent extreme weather events, flood disasters have led to growing losses and casualties, highlighting the importance of understanding pedestrian dynamics in flooded environments.
Xintong Li, Weiguo Song, Jun Zhang, Nikolai W.F. Bode   +3 more
doaj   +1 more source

Intrinsically Mitochondria‐Targeting Nanozyme via Coordination‐Assembly of Natural Quercetin for Cascade Antioxidant Therapy of Cerebral Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
This study uncovers that quercetin naturally targets mitochondria. By coordinating quercetin with Fe3+, we engineer an ultrasmall cascade nanozyme (MCN) with superoxide dismutase‐catalase activities. MCN crosses the damaged blood–brain barrier, scavenges mitochondrial ROS, prevents mitochondrial DNA leakage, and blocks the cGAS‐STING pathway, thereby ...
Wenxuan Zheng, Zhicheng Wang, Xin Zhou, Shuya Wang, Xiaojing Shi, Tingli Xiong, Ruishi Li, Yuting Lin, Zhen Chen, Jiawen Wei, Fei Li, Jinwen Ge, Kelong Ai, Chong Liu, Guiming Deng   +14 more
wiley   +1 more source

QUANTITATIVE ANALYSIS ON THE MUSCULAR ACTIVITY OF LOWER EXTREMITY DURING WATER WALKING

, 2009
This study compared water walking (WW) with land walking (LW) in order to evaluate the muscular activities of the lower extremity. Nine young healthy subjects performed WW at voluntary slow, normal and fast speeds for 8 seconds with two repetitions.
Ohgi, Y., Sato, D., Kaneda, K., Wakabayashi, H., Nomura, T.   +4 more
core   +1 more source

Kinematic Adaptations of Forward And Backward Walking on Land and in Water

The aim of this study was to compare sagittal plane lower limb kinematics during walking on land and submerged to the hip in water. Eight healthy adults (age 22.1 ± 1.1 years, body height 174.8 ± 7.1 cm, body mass 63.4 ± 6.2 kg) were asked to cover a ...
Cadenas-Sanchez, C, Lopez-Contreras, G, Vanrenterghem, J, Arellano, R   +3 more
core   +1 more source

EMG analysis of the influence of the water environment on walking in the elderly [PDF]

, 2015
Title: EMG analysis of the influence of the water environment on walking in the elderly Objectives: The main objective of this master thesis is to determine the degree of activation of selected muscles during walking on land and in water environment by ...
Vodičková, Kamila
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