Results 31 to 40 of about 3,154 (208)

Primary squamous cell carcinoma of pancreas mimicking walled-off pancreatic necrosis

Journal of Digestive Endoscopy, 2016
Pancreatic carcinoma is a dreaded diagnosis due to its poor prognosis. Squamous cell carcinoma (SCC) of the pancreas is a rare histological variety of pancreatic carcinoma. Its diagnosis is based on ruling out other site of tumor origin.
Deepak Gunjan, Surinder Singh Rana, Puneet Chhabra, Rahul Vithalrao Parghane, Rajesh Kumar, Lovneet Dhalaria, Bhawant R. Mittal, Deepak K. Bhasin   +7 more
doaj   +1 more source

Recent Advances in Light‐Addressable Electrochemistry for Spatially Resolved Applications

Advanced Materials Technologies, EarlyView.
This comprehensive review highlights light‐addressable electrochemistry as a powerful tool that uses light to control localized chemical reactions on unstructured semiconductor surfaces. The work evaluates advanced strategies to optimize electrode materials for enhanced spatial resolution and stability. Furthermore, it showcases diverse applications in
Nhi Trang Vo, Sina Jamali, Nam‐Trung Nguyen   +2 more
wiley   +1 more source

Single‐Dose TACE‐Like Injection of Sustained‐Release Panobinostat/IL‐12 Polymeric Microparticles is Effective in Preclinical Liver Cancer Models

Advanced Science, EarlyView.
A novel PLGA/PBAE polymer microparticle platform revolutionizes intermediate‐stage liver cancer treatment by co‐delivering panobinostat and IL‐12 via a single TACE‐like injection. This sustained‐release system overcomes tumor immunosuppression, triggers robust innate and adaptive immune responses, and establishes tertiary lymphoid structures ...
Hongzhe Yu, Ling Li, Sachin S. Surwase, Xin Ming M. Zhou, Hongtao Qian, Joel C. Sunshine, Florin M. Selaru, Jordan J. Green   +7 more
wiley   +1 more source

The role of the host—Neutrophil biology

Periodontology 2000, EarlyView., 2023
Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple, Josefine Hirschfeld, Alpdogan Kantarci, Asaf Wilensky, Lior Shapira   +4 more
wiley   +1 more source

Guidewire‐assisted successful closure of mis‐punctured transverse colon during endoscopic ultrasound‐guided cyst drainage

DEN Open
Endoscopic ultrasound‐guided cyst drainage (EUS‐CD) was performed for walled‐off pancreatic necrosis. Computed tomography performed the next day showed that the tip of the external drainage tube was located in the transverse colon, confirming an ...
Naoki Fujita, Hideki Kamada, Ryota Nakabayashi, Takuma Yamashita, Shima Mimura, Hiroki Yamana, Kiyoyuki Kobayashi, Minoru Oshima, Keiichi Okano, Hideki Kobara   +9 more
doaj   +1 more source

Acute Necrotising Pancreatitis with Walled-off Necrosis Complicated by Left Renal Vein Thrombosis: A Case Report [PDF]

Journal of Clinical and Diagnostic Research
Acute necrotising pancreatitis represents a severe form of pancreatic inflammation associated with substantial morbidity and mortality, particularly when complicated by walled-off necrosis and vascular thrombosis.
Jaypradha Saravanan, Sakthi Ganesh Subramonian, Hitha Almengada Ravi, Karthik Krishna Ramakrishnan, Paarthipan Natarajan   +4 more
doaj   +1 more source

Extended Open Transgastric Necrosectomy (EOTN) as a Safer Procedure for Necrotizing Pancreatitis [PDF]

Journal of Clinical and Diagnostic Research, 2014
The treatment of infected necrotizing pancreatitis has evolved from time to time and the success of surgical intervention depends on the timing of necrosectomy. Bacterial infection occurs in 40–70% of patients with necrotizing pancreatitis. Infection is
Prasad Sasnur, Ravindra Nidoni, Ramakanth Baloorkar, Vikram Sindgikar, Bharat Shankar   +4 more
doaj   +1 more source

Natural Product Toosendanin Suppresses the Malignant Development of Skin Melanoma by Targeting BNC2 for Degradation

Advanced Science, EarlyView.
BNC2 exhibits context‐dependent opposing functions across multiple cancer types. This study reveals BNC2 as an oncogenic driver of melanoma proliferation and metastasis through transcriptional activation of PIK3CA. The natural compound TSN simultaneously degrades BNC2 and its oncogenic partner SMAD3 via CRBN‐dependent ubiquitination.
Hui Dai, Xin Mei Zhang, Jing Cheng Zhang, Xu Ting Deng, Qiao Liu, Mustafa Hussein Ali, Fang Zhou Yin, Wu Yin   +7 more
wiley   +1 more source

Pancreatic parenchymal calcification induced by permanent indwelling transmural stent

JGH Open, 2019
Long‐term transmural stent placement is a safe and effective strategy for the prevention of recurrence of pancreatic fluid collection in patients with walled‐off necrosis and disconnected pancreatic duct syndrome.
Surinder S Rana, Ravi Sharma, Rajesh Gupta   +2 more
doaj   +1 more source

NCLX Inhibition plus Ca2+ Delivery Potentiates Electroporation and Antitumor Immunity in Pancreatic Ductal Adenocarcinoma

Advanced Science, EarlyView.
Electroporation combined with NCLX inhibition and Ca2+ delivery induces mitochondrial Ca2+ overload in PDAC cells, triggering pyroptosis, DAMP release, and antitumor immune activation. Simultaneously, suppression of tumor‐derived SPP1 weakens SPP1–CD44 signaling and remodels macrophages toward an antitumor phenotype, thereby enhancing CD8+ T‐cell ...
Chuanbing Zhao, Long He, Yu Lu, Zanglong Deng, Hongzhen Wei, Yunpeng Zhang, Ming Yang, Tao Yin   +7 more
wiley   +1 more source