Results 251 to 260 of about 323,634 (294)

Wallerian degeneration as a window to peripheral neuropathy

Journal of the Neurological Sciences, 2004
Wallerian degeneration represents axonal degeneration in its purest form. When a nerve fiber is transected, a series of events is set in motion that results in dissolution of the distal axon, remodeling of the nerve fiber constituents (i.e., Schwann cells, basal lamina) and ultimately regeneration of the fiber by growth of new axons.
openaire   +2 more sources

Wallerian degeneration and neuropathic pain

Drug Discovery Today: Disease Mechanisms, 2006
Wallerian degeneration is a stereotype reaction of the peripheral nervous system to different kinds of nerve injury. This auto-destructive process is frequently associated with neuropathic pain, which can be very severe and resistant to treatment. The bridging factors between Wallerian degeneration and neuropathic pain are incompletely understood. Here
Nurcan Üçeyler, Claudia Sommer
openaire   +2 more sources

Indirect Wallerian Degeneration

1974
After a mechanical lesion of a nerve fibre the part of the fibre distal to the lesion undergoes degenerative changes, so-called Walleriandegeneration. Prominent changes also take place in the fibre parts immediately adjacent to the lesion, the trauma zone (Cajal, 1928 a, b).
openaire   +2 more sources

Diffusion-weighted imaging in Wallerian degeneration

Journal of the Neurological Sciences, 2000
We report two patients displaying hyperintensities on diffusion-weighted imaging (DWI) in the area of Wallerian degeneration (WD) at 12 days after stroke. High signal intensities were more conspicuous on DWI than on T2-weighted images. Both patients showed decreased diffusion anisotropy resulting in elevated apparent diffusion coefficient in the area ...
Byung-Woo Yoon, Kon Chu, Dong-Wha Kang, In Chan Song, Jae-Kyu Roh, Kee-Hyun Chang   +5 more
openaire   +3 more sources

Wallerian degeneration: evaluation with MR imaging.

Radiology, 1988
Twenty-three patients who underwent routine magnetic resonance (MR) imaging of the brain were found to have signal or structural abnormalities corresponding to white matter tracts. Images were evaluated for anatomic and MR signal characteristics of the involved tract, associated primary lesions, and, when possible, changes in MR signal and anatomic ...
M J Kuhn, Kenneth R. Davis, Keith A. Johnson   +2 more
openaire   +3 more sources

Direct Wallerian Degeneration

1974
In the previous study (Part I) a description was given of the ultrastructural changes occurring during indirect Wallerian degeneration in the intramedullary root fibre region of the kitten hypoglossal nerve. One of the striking features of this degeneration process was the appearance at an early stage of microglial cells completely covered by myelin ...
openaire   +2 more sources

SIRT6 Negatively Regulates Schwann Cells Dedifferentiation via Targeting c-Jun During Wallerian Degeneration After Peripheral Nerve Injury

Molecular Neurobiology, 2021
Ying Zou, Jiaqi Zhang, Jingmin Liu, Jiawei Xu, L. Fu, Xinrui Ma, Yizhou Xu, Shuyi Xu, Xianghai Wang, Jiasong Guo   +9 more
semanticscholar   +1 more source

Wallerian degeneration in the optic nerve stretch-injury model of traumatic brain injury: a stereological analysis.

Journal of Neurotrauma, 2015
Patients with chronic traumatic encephalopathy (CTE) show loss of central white matter, central gray matter, and cortical gray matter with increasing post-traumatic survival.
William L. Maxwell, Emma Bartlett, Hanna Morgan   +2 more
semanticscholar   +1 more source

CHEMISTRY OF WALLERIAN DEGENERATION

Archives of Neurology & Psychiatry, 1950
DEMYELINATION, or the destruction of the myelin sheath of nerve fibers, is a prominent characteristic of many neurologic disorders. An understanding of the chemical changes associated with demyelination is obviously desirable. A study of these changes is practicable only if there is available a ready means of producing the destruction of "myelin ...
A. R. McNabb, A. C. Johnson, R. J. Rossiter   +2 more
openaire   +3 more sources

WALLERIAN DEGENERATION IN THE RAT A CHEMICAL STUDY

Canadian Journal of Medical Sciences, 1952
The wet weight of the sciatic nerve of the rat increased as the nerve degenerated after nerve section. At the same time the concentration of nucleic acid increased and the concentration of total phospholipid, sphingomyelin (phosphosphingoside), and free cholesterol decreased.
openaire   +3 more sources