Results 1 to 10 of about 563,945 (203)

Military and Medical Expertise in Patients with Central Retinal Degeneration [PDF]

International Journal of Clinical and Experimental Medical Sciences, 2018
Last years pathological processes of the retina became a worldwide problem among people of different ages and this group includes a various number of central retinal degenerations. There is a vivid tendency for these types of diseases to become younger last years.
exaly   +2 more sources

Medication Trends for Age-Related Macular Degeneration [PDF]

International Journal of Molecular Sciences, 2021
Age-related macular degeneration (AMD) is central vision loss with aging, was the fourth main cause of blindness in 2015, and has many risk factors, such as cataract surgery, cigarette smoking, family history, hypertension, obesity, long-term smart device usage, etc. AMD is classified into three categories: normal AMD, early AMD, and late AMD, based on
Yeon-Kyoung Cho, Dae-Hun Park, In-Chul Jeon   +2 more
openaire   +2 more sources

Enhancing medical explainability in deep learning for age-related macular degeneration diagnosis

Scientific Reports
Deep learning models hold significant promise for disease diagnosis but often lack transparency in their decision-making processes, limiting trust and hindering clinical adoption. This study introduces a novel multi-task learning framework to enhance the medical explainability of deep learning models for diagnosing age-related macular degeneration (AMD)
exaly   +4 more sources

Retraction Note: PAX8-AS1 knockdown facilitates cell growth and inactivates autophagy in osteoblasts via the miR-1252-5p/GNB1 axis in osteoporosis [PDF]

Experimental and Molecular Medicine
Caiqiang Huang, Runguang Li, Changsheng Yang, Rui Ding, Qingchu Li, Denghui Xie, Rongkai Zhang, Yiyan Qiu   +7 more
doaj   +2 more sources

Caffeine Inhibits Oxidative Stress- and Low Dose Endotoxemia-Induced Senescence—Role of Thioredoxin-1

Antioxidants, 2023
The maintenance of Thioredoxin-1 (Trx-1) levels, and thus of cellular redox homeostasis, is vital for endothelial cells (ECs) to prevent senescence induction.
Dennis Merk, Jan Greulich, Annika Vierkant, Fiona Cox, Olaf Eckermann, Florian von Ameln, Nadine Dyballa-Rukes, Joachim Altschmied, Niloofar Ale-Agha, Philipp Jakobs, Judith Haendeler   +10 more
doaj   +1 more source

Protective Effects of Curcumin in Cardiovascular Diseases—Impact on Oxidative Stress and Mitochondria

Cells, 2022
Cardiovascular diseases (CVDs) contribute to a large part of worldwide mortality. Similarly, two of the major risk factors for these diseases, aging and obesity, are also global problems.
Fiona Frederike Cox, Angelina Misiou, Annika Vierkant, Niloofar Ale-Agha, Maria Grandoch, Judith Haendeler, Joachim Altschmied   +6 more
doaj   +1 more source

Selenoprotein T Protects Endothelial Cells against Lipopolysaccharide-Induced Activation and Apoptosis

Antioxidants, 2021
Sepsis is an exaggerated immune response upon infection with lipopolysaccharide (LPS) as the main causative agent. LPS-induced activation and apoptosis of endothelial cells (EC) can lead to organ dysfunction and finally organ failure.
Dennis Merk, Johannes Ptok, Philipp Jakobs, Florian von Ameln, Jan Greulich, Pia Kluge, Kathrin Semperowitsch, Olaf Eckermann, Heiner Schaal, Niloofar Ale-Agha, Joachim Altschmied, Judith Haendeler   +11 more
doaj   +1 more source

Non-medical treatment for late age-related macular degeneration [PDF]

Russian Journal of Clinical Ophthalmology, 2021
Age-related macular degeneration (AMD) is the leading cause of blindness in people over 55 in developed countries. Moreover, the number of these patients will increase growth as life expectancy increases. It is estimated that late AMD accounts for half of blindness and low vision cases in European countries. A myriad of studies is currently underway to
A.K. Drakon, A.G. Kurguzova, V.M. Sheludchenko, N.B. Korchazhkina   +3 more
openaire   +2 more sources

Choosing the right animal model for osteomyelitis research: Considerations and challenges

Journal of Orthopaedic Translation, 2023
Osteomyelitis is a debilitating bone disorder characterized by an inflammatory process involving the bone marrow, bone cortex, periosteum, and surrounding soft tissue, which can ultimately result in bone destruction.
Shen Huang, Jing Wen, Yiqing Zhang, Xiaochun Bai, Zhong-Kai Cui   +4 more
doaj   +1 more source

Early calcific degeneration of the St. Jude Medical Epic aortic bioprosthesis [PDF]

Clinical Case Reports, 2020
AbstractThis report highlights the need for close surveillance of bioprosthetic valves. Unaccountable degeneration of bioprosthetic valves can develop early after implantation and usually requires replacing the failed valve with a mechanical prosthesis.
Mohammad Bashar Izzat, Nada Sabbagh, Hazem Aljasem   +2 more
openaire   +3 more sources