Results 91 to 100 of about 250,968 (293)

Multi-color photonic integrated circuits based on homogeneous integration of quantum cascade lasers

open access: yesNature Communications
We demonstrate an InP-based mid-infrared photonic integrated circuit processed from a wafer in which two distinct quantum cascade laser active regions are grown in different areas on the same InP crystal. A passive InGaAs waveguiding layer is epitaxially
Dominik Burghart   +5 more
doaj   +1 more source

Graman Revisited Once Again: A Reanalysis of the Late Holocene Legacy Faunal Assemblage From GB4 Rockshelter, New South Wales

open access: yesArchaeology in Oceania, EarlyView.
ABSTRACT The archaeological site Graman B4 provided one of the first records of substantial dietary change in ancient Australian Aboriginal society. Initial examination of the faunal remains from this site suggested that Late Holocene hunters reduced their focus on high‐ranked kangaroos to increasingly rely on arboreal possums; and that these ...
Loukas George Koungoulos   +2 more
wiley   +1 more source

Risk Factors for Relapse in Antineutrophil Cytoplasmic Antibody–Associated Vasculitis Among Patients With Relapse After Induction of Remission With Rituximab

open access: yesArthritis &Rheumatology, EarlyView.
Objective The objective of the study was to determine risk factors for relapse of antineutrophil cytoplasmic antibody (ANCA)–associated vasculitis (AAV) after reinduction of remission with rituximab and discontinuation of maintenance therapy. Methods This is a post hoc analysis of the RITAZAREM clinical trial.
Ellen Romich   +62 more
wiley   +1 more source

Measuring the Impact: Magnetic Resonance Imaging Response of Sacroiliac Joints to Tumor Necrosis Factor Inhibitors in Youth With Axial Disease

open access: yesArthritis &Rheumatology, EarlyView.
Objective To evaluate the timeline for resolution of sacroiliac joint (SIJ) inflammation, changes in structural lesions, and their correlation with patient‐reported outcomes (PROs) in youth with axial juvenile spondyloarthritis (axJSpA) initiating tumor necrosis factor inhibitor (TNFi).
Timothy G. Brandon   +8 more
wiley   +1 more source

Mutational profiling of SARS-CoV-2 papain-like protease reveals requirements for function, structure, and drug escape

open access: yesNature Communications
Papain-like protease (PLpro) is an attractive drug target for SARS-CoV-2 because it is essential for viral replication, cleaving viral poly-proteins pp1a and pp1ab, and has de-ubiquitylation and de-ISGylation activities, affecting innate immune responses.
Xinyu Wu   +12 more
doaj   +1 more source

Discussion: “Elements of a General Theory of Airplane-Wing Design” (Durfee, Walter C., 1919, Trans. ASME, 41, pp. 465–471) [PDF]

open access: bronze, 1919
John R. Freeman   +5 more
openalex   +1 more source

Activism as education in and through the youth climate justice movement

open access: yesBritish Educational Research Journal, EarlyView.
Abstract Young people worldwide are increasingly participating in a global movement for climate justice, yet to date, little research has examined how youth climate justice activists conceive of and experience activism as education. The present study used in‐depth, semi‐structured interviews with 16 US climate justice activists (aged 15–17) to address ...
Carlie D. Trott
wiley   +1 more source

How can welfare regime and production regime theories explain differences in schools’ ability grouping policies? A comparative study using the PISA school survey

open access: yesBritish Educational Research Journal, EarlyView.
Abstract Research evidence is mixed on the consequences of ability grouping policies, but most research has found an overrepresentation of disadvantaged social demographics in low‐ability groups. However, researchers have neglected to explain why ability grouping policies vary between countries.
Monica Reichenberg   +2 more
wiley   +1 more source

High-throughput drug screening identifies EGFR/MAPK pathway targeting sensitivities in organoid models of ovarian carcinosarcoma

open access: yesJournal of Experimental & Clinical Cancer Research
Background Ovarian carcinosarcoma (OCS) is a rare and aggressive tumour type with limited treatment options. Standard therapy includes platinum agents, but responses are poor. OCS highly express mesenchymal markers, such as N-MYC and HMGA2.
Andrew Farrell   +20 more
doaj   +1 more source

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