Results 111 to 120 of about 2,527,757 (302)
Arthritis &Rheumatology, Accepted Article.Background Individuals with systemic autoimmune rheumatic diseases (SARDs) are at risk for worse acute and post‐acute COVID‐19 outcomes, though whether individuals with SARDs have longer persistence of viral antigens after COVID‐19 has not been studied.
Naomi J. Patel +18 more
wiley +1 more source
Volume 13, Number 4 - January 1933 [PDF]
, 1933 Volume 13, Number 4 – January 1933. 22 pages including covers and advertisements. Poole, Jr., Frederick E. What A Night Gove, Leslie The Storm Over Asia Popkin, George, Vengeance Is Mine More Melange - Two Essays Shunney, Walter J.
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Anterior Cruciate Ligament Repair: Surgical Technique Using Augmentation With Biocomposite Scaffold
Arthroscopy Techniques, EarlyView.Abstract Repair of the anterior cruciate ligament has recently regained interest over the past decade. Such repairs can be augmented with nonabsorbable suture for strength or biologic scaffolds to promote healing. This technique uses the BioBrace, a porous 3‐dimensional collagen scaffold made from bioresorbable bovine type I collagen that is reinforced
Caleb Berta +6 more
wiley +1 more source
Transcriptomic changes including p53 dysregulation prime DNMT3A mutant cells for transformation
EMBO ReportsDNMT3A mutations are prevalent in haematologic malignancies. In our mouse model the murine homologue (R878H) of the human ‘hotspot’ R882H mutation is introduced into the mouse Dnmt3a locus. This results in globally reduced DNA methylation in all tissues.
Erin M Lawrence +18 more
doaj +1 more source
British Journal of Clinical Pharmacology, EarlyView.Aims Ginisortamab, a first‐in‐class human monoclonal antibody for the treatment of advanced solid tumours, binds to gremlin‐1 and restores bone morphogenetic protein signalling. We used pharmacokinetic/pharmacodynamic (PK/PD) modelling to characterize the relationship between ginisortamab dose and serum gremlin‐1 binding, using model‐based simulations ...
Yin Cheong Wong +6 more
wiley +1 more source
Volume 13, Number 7 – April 1933 [PDF]
, 1933 Volume 13, Number 7 – April 1933. 22 pages including covers and advertisements. Connolly, Paul F., It\u27s More Fun to Know McGuiness, Joseph D., The Boar of the Borgias LaCroix, John L., Easter Gossip Challenge The End of Time Murray ...
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Activism as education in and through the youth climate justice movement
British Educational Research Journal, EarlyView.Abstract Young people worldwide are increasingly participating in a global movement for climate justice, yet to date, little research has examined how youth climate justice activists conceive of and experience activism as education. The present study used in‐depth, semi‐structured interviews with 16 US climate justice activists (aged 15–17) to address ...
Carlie D. Trott
wiley +1 more source
A tale of (at least) two cities [PDF]
, 2008 Modernism is built on a foundation of the double, the facsimile and similitude – the repetitions of the machine age. Model T-Fords, Motel chains and Fast Food restaurants are the most obvious – most digestible? – remnants of the modernist production line.
Davies, Colin, Parrinder, Monika
core
Raman Spectroscopy–Based Glucose Feed Control Automates Malic Acid Fermentation
Biotechnology and Bioengineering, EarlyView.Raman spectroscopy enables automated, closed‐loop glucose feeding for malic acid production with Ustilago trichophora. Online PLS regression of glucose and malic acid provides input for PID control to maintain 20 g/L glucose. The feed is dynamically adjusted and stopped in response to metabolic demand and product inhibition, demonstrating practical ...
Luca Antonia Grebe +8 more
wiley +1 more source
Nature CommunicationsPapain-like protease (PLpro) is an attractive drug target for SARS-CoV-2 because it is essential for viral replication, cleaving viral poly-proteins pp1a and pp1ab, and has de-ubiquitylation and de-ISGylation activities, affecting innate immune responses.
Xinyu Wu +12 more
doaj +1 more source