Results 21 to 30 of about 2,527,757 (302)

Reconceptualising initial teacher education in South Africa: A quest for transformative and sustainable alternatives

Interdisciplinary Journal of Education Research
Education serves as a catalyst for achieving Sustainable Development Goals (SDGs), and it is essential for education to keep pace with societal dynamics.
Clever Ndebele, Newlin Marongwe, Thobeka Ncanywa, Samson Matope, Zanele Ginyigazi, Grasia Chisango, Phumla Nomatolo Msindwana, Rufaro Garidzirai   +7 more
doaj   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Oct2 and Obf1 as facilitators of B:T cell collaboration during a humoral immune response

Frontiers in Immunology, 2014
The Oct2 protein, encoded by the Pou2f2 gene, was originally predicted to act as a DNA binding transcriptional activator of immunoglobulin (Ig) in B lineage cells.
Lynn M Corcoran, Dianne eEmslie, Tobias eKratina, Wei eShi, Susanne eHirsch, Nadine eTaubenheim, Stephane eChevrier   +6 more
doaj   +1 more source

Study of a Character [PDF]

, 2015
Non-fiction by Walter O ...
Carter, Walter O.
core   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Hexachlorophene as a topically applied chemical for prophylaxis against Schistosoma mansoni infections in mice

Revista do Instituto de Medicina Tropical de São Paulo, 1985
Treatment of mouse tail skins with hexachlorophene (1.25% w/v) in absolute methanol or 70% isopropanol suppressed Schistosoma mansoni infections by more than 95% even when the application was performed up to three days prior to exposure to cercarial ...
Marie M. Grenan, Lyfford K. Greene, David E. Davidson Jr., Douglas H. Jones, Tommy R. Shedd, Gregory Hiestand   +5 more
doaj   +1 more source

Une Larme [PDF]

, 1919
Transcribed for violin with piano accompaniment by A. Walter Kramer.
Mussorgsky, Modest Petrovich
core   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Influence of a seed-funded community of practice on the development of academic staff research at a comprehensive University in South Africa

Interdisciplinary Journal of Education Research
This study seeks to explore the influence of a seed-funded project on the research development, professional growth, and collaboration of academic staff.
Israel Kariyana, Neliswa Gqoli, Ifeanyi Mbukanma, Nontuthuzelo Cekiso-Smith, Bongeka Nosisi Kauleza, Bafundi Zealous Mapisa, Jongiwe Tebekana   +6 more
doaj   +1 more source

PacBio long-read amplicon sequencing enables scalable high-resolution population allele typing of the complex CYP2D6 locus

Communications Biology, 2022
PLASTER is a broadly-applicable data processing pipeline that enables robust allele typing of SMRT-sequenced amplicons, as evidenced by allele typing of the CYP2D6 gene in a cohort from the Solomon Islands.
Sarah Charnaud, Jacob E. Munro, Lucie Semenec, Ramin Mazhari, Jessica Brewster, Caitlin Bourke, Shazia Ruybal-Pesántez, Robert James, Dulcie Lautu-Gumal, Harin Karunajeewa, Ivo Mueller, Melanie Bahlo   +11 more
doaj   +1 more source