Results 111 to 120 of about 62,451 (349)

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Killing the news: Photographer Paul Conroy, who worked with Sunday Times correspondent Marie Colvin, says editors struggle to cover war zones now [PDF]

, 2018
Ryan McChrystal
openalex   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Skamandryckie listy na emigracji – garść informacji o korespondencji Jana Lechonia, Kazimierza Wierzyńskiego i Mieczysława Grydzewskiego

Napis, 2020
The article presents the state of preservation of the correspondence between the representatives of the Skamander poetry group: Jan Lechoń and Kazimierz Wierzyński, as well as Mieczysław Grydzewski, the editor of ‘Skamander’.
Beata Dorosz
doaj  

Ukraine Crisis: Russian-Ukrainian War through the vision of BBC News correspondents

, 2021
Vitalii Telvak, В. Масненко
openalex   +2 more sources

You Will Be Harassed and Detained: Media Freedoms Under Assault in China Ahead of the 2008 Beijing Olympic Games [PDF]

, 2008
This 40-page report documents how Chinese authorities have repeatedly obstructed the work of foreign journalists this year, even though China on January 1, 2007, adopted temporary regulations to comply with commitments it made to the International ...

core  

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Associations among traumatic experiences, threat exposure, and mental health in Pakistani journalists. [PDF]

J Trauma Stress, 2022
Koster SM, Koot HM, Malik JA, Sijbrandij M.   +3 more
europepmc   +1 more source

Foreign Correspondents in the Cold War [PDF]

, 2019
Sune Bechmann Pedersen, Marie Cronqvist
openalex   +1 more source